Is nasopharyngeal carcinoma contagious?

Written by Li Rui
Otolaryngology
Updated on September 11, 2024
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Nasopharyngeal carcinoma currently has no definite transmissibility, and the exact cause of nasopharyngeal cancer is not particularly clear. Clinical studies have shown that there is a certain relationship between nasopharyngeal carcinoma and EB virus infection, but it may also be related to other factors, such as familial heredity or living environment. Exposure to radioactive or chemical substances may also have a certain impact. Currently, there is no evidence to suggest that there is genetic or absolute contagion. Overall, in terms of treatment, radiotherapy is mainly used, and some patients need to be combined with chemotherapy. Generally, the five-year survival rate is relatively high among early-stage patients. If the disease staging is later and the differentiation is poor, the treatment difficulty and treatment effect are relatively worse.

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Written by Li Rui
Otolaryngology
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Can nasopharyngeal cancer be cured?

A portion of nasopharyngeal carcinoma patients can meet the criteria for clinical cure. It largely depends on the specific staging and type of the cancer. Patients with higher differentiation and earlier stages, especially stages one and two, tend to have better treatment outcomes. Currently, radiation therapy is the primary treatment, and some patients may also need to undergo chemotherapy. Overall, chemotherapy is quite effective for most patients. However, whether clinical cure can be achieved primarily depends on the extent of the disease and individual differences. Some people respond better to radiotherapy and chemotherapy, which in turn increases their chances of clinical cure. The five-year survival rate is considered the most important indicator.

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Written by Deng Bang Yu
Otolaryngology
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What are the symptoms of late-stage nasopharyngeal carcinoma?

Nasopharyngeal cancer is a common malignancy in otolaryngology, primarily located in the nasopharyngeal area. In advanced stages, nasopharyngeal cancer manifests symptoms in two main aspects. One involves symptoms directly caused by the cancer or its metastasis, typically presenting as increased nasal masses, enlarged cervical lymph nodes, severe headaches, decreased hearing, and bleeding in the nasal area due to tumor cells or tissue eroding the internal carotid artery. Additionally, there is a foul smell from the nasopharyngeal area. The second aspect relates to systemic symptoms due to the growth of nasopharyngeal cancer, leading to poor overall nutritional status and cachexia, characterized by extreme emaciation. There is also the potential for distant metastasis of the tumor cells, presenting symptoms in the corresponding areas.

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Written by Deng Bang Yu
Otolaryngology
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What are the symptoms of nasopharyngeal carcinoma?

Nasopharyngeal carcinoma is a malignant, space-occupying lesion in our nasopharynx. Clinically, the initial symptoms are those of the nasopharynx, manifesting as discomfort in the nasopharyngeal area, or blood in nasal discharge when sniffling. As the nasopharyngeal carcinoma tissue enlarges, it can block the posterior nasal apertures, leading to nasal congestion, rapid breathing, and difficulty in breathing. The tumor tissue pressing on our Eustachian tube can cause secretory middle ear infections. The metastasis of nasopharyngeal carcinoma cells to our cervical lymph nodes causes swelling of these lymph nodes. Destruction of the cranial structure by nasopharyngeal carcinoma tissues presents symptoms such as headaches. There are also other symptoms, mainly due to the spread of nasopharyngeal carcinoma throughout the body or its metastasis to other parts causing corresponding symptoms.

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Written by Deng Bang Yu
Otolaryngology
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How to check for nasopharyngeal carcinoma?

Nasopharyngeal carcinoma is a malignant tumor in the nasal area, clinically mainly squamous cell carcinoma. The incidence of nasopharyngeal carcinoma is relatively high in southern regions of our country. Clinically, the primary treatment is radiotherapy. For diagnosis, the first general step involves using an electronic nasopharyngoscope to examine the nasopharyngeal area for suspicious conditions. Further imaging studies can also be conducted, such as CT scans and MRI scans of the nasopharyngeal area. Through these examinations, if a neoplasm in the nasal area is essentially identified and suspected to be nasopharyngeal carcinoma, an endoscopic examination is conducted where forceps are used to clip tissue for a pathological biopsy. The pathological biopsy determines whether it is definitively nasopharyngeal carcinoma and identifies the type of cancer cells, thus guiding clinical treatment.

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Written by Yao Jun
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Causes of Nasopharyngeal Carcinoma

Nasopharyngeal carcinoma is a highly prevalent malignant tumor in China, especially common in the Guangdong and Guangxi regions, as well as other coastal areas including Hunan, Fujian, and Jiangxi. These regions are among the highest incidence areas for nasopharyngeal carcinoma worldwide. The incidence rate in males is three times that of females, with the age group of 40 to 50 years being particularly at risk. The occurrence of nasopharyngeal carcinoma is associated with genetic, viral, and environmental factors, exhibiting racial and familial patterns. In areas like Guangzhou and the Pearl River Delta, it is possible for five out of nine people in the same family to have nasopharyngeal carcinoma. Infection with the Epstein-Barr virus is also one of the causes of nasopharyngeal carcinoma, in addition to environmental factors. Areas with low trace elements in rice and water, as well as low fluoride levels, are prone to higher incidences of this cancer. Patients with nasopharyngeal carcinoma typically have higher fluoride levels in their hair, and nitrites are also one of the major contributing factors to the condition.