Distinction between Nasopharyngitis and Nasopharyngeal Carcinoma

Written by Deng Bang Yu
Otolaryngology
Updated on September 20, 2024
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Nasopharyngitis and nasopharyngeal carcinoma have fundamental differences. Nasopharyngitis is an inflammatory disease, while nasopharyngeal carcinoma is a malignant tumor disease. Clinically, nasopharyngitis mainly presents with increased secretions in the nasopharyngeal area, sometimes with a slight amount of bloody secretions, but this is extremely rare. On the other hand, nasopharyngeal carcinoma primarily shows symptoms such as the proliferation of malignant tumor tissues in the nasopharynx, enlargement of the lymph nodes in the neck, headaches, and ear stuffiness. In terms of treatment, nasopharyngitis is primarily treated with medications, such as traditional Chinese medicines, nasal sprays, and nasal corticosteroids; whereas nasopharyngeal carcinoma is primarily treated with radiotherapy combined with chemotherapy, which is currently the common sandwich therapy. Overall, there are fundamental differences between the two.

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What should I do if nasopharyngeal carcinoma causes vomiting?

Patients with nasopharyngeal carcinoma who exhibit vomiting should first determine the cause of the vomiting. For instance, if vomiting is due to the gastrointestinal reactions caused by radiotherapy and chemotherapy, medications such as serotonin receptor antagonists, corticosteroids, and NK-1 receptor blockers should be used to alleviate the side effects of the treatment. Additionally, nasopharyngeal carcinoma patients might experience projectile vomiting due to brain metastasis, which results in increased intracranial pressure. It is essential first to confirm the presence of brain metastasis through CT and MRI scans of the head. If brain metastasis is confirmed, localized treatment such as radiotherapy should be administered. Medications like mannitol and glycerol fructose should be used concurrently to reduce intracranial pressure and relieve the projectile vomiting. (Please use medications under the guidance of a doctor.)

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The Difference between Nasopharyngitis and Nasopharyngeal Carcinoma

The differences between nasopharyngitis and nasopharyngeal carcinoma are very clear. Firstly, nasopharyngitis is an acute inflammatory irritation, while the cause of nasopharyngeal carcinoma is currently unknown, generally associated directly with EB virus infection. Secondly, their clinical manifestations are different. Patients with nasopharyngitis may experience dryness and pain in the nasopharyngeal area, and yellow secretions may occur when clearing the throat in the morning. In contrast, nasopharyngeal carcinoma typically presents as a painless mass. During examination with a nasopharyngoscope, the surface of nasopharyngitis is congested and swollen, whereas in nasopharyngeal carcinoma, cauliflower-like neoplasms or ulcers can be found at the top of the nasopharynx or near the pharyngeal recess. A local pathological examination can reveal symptoms and clarify the diagnosis. In terms of treatment, nasopharyngitis requires symptomatic anti-inflammatory treatment, while nasopharyngeal carcinoma requires local radiotherapy or chemotherapy.

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Can nasopharyngeal cancer be cured?

Nasopharyngeal carcinoma is a relatively common type of head and neck malignant tumor. Currently, radiation therapy is commonly used for treatment. Depending on the severity of the patient's condition, some patients may also need to combine chemotherapy. The specific treatment effectiveness varies from individual to individual, and some patients can achieve clinical cure. For early-stage nasopharyngeal carcinoma, the treatment effectiveness is relatively good, and the clinical cure rate is comparatively high. For mid to late-stage nasopharyngeal carcinoma, the treatment becomes more challenging, and the treatment effectiveness is relatively poorer. After treatment, regular check-ups are required to monitor the recovery of the condition. If no recurrence or distant metastasis is found five years after treatment, the patient is considered clinically cured.

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Can late-stage nasopharyngeal carcinoma be cured?

Nasopharyngeal cancer is a malignant tumor located in the nasopharynx. Late-stage nasopharyngeal cancer refers to stages three and four, particularly stage four, where the patient experiences destruction of adjacent tissue structures and metastasis to distant organs. In such cases, clinical treatment generally involves symptomatic management or palliative care, aimed at improving the patient's quality of life and alleviating suffering. Whether nasopharyngeal cancer, especially in its late stages, can be cured is highly uncertain; its prognosis is very poor, and no one can definitively answer if it can be cured. However, the chances of cure are extremely slim, and the main approach is to provide palliative treatments.

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Is nasopharyngeal carcinoma prone to metastasis?

Nasopharyngeal carcinoma is a relatively common type of malignant tumor in the head and neck area and is prone to metastasis. The most common metastasis site is the cervical lymph nodes. Some patients are diagnosed with nasopharyngeal carcinoma only after the discovery of cervical lymph node metastatic cancer. Additionally, some patients may experience intracranial metastasis or bone metastasis. Generally speaking, for patients with nasopharyngeal carcinoma, it is crucial to achieve early detection, early diagnosis, and early treatment. After treatment, long-term regular follow-up is necessary to help determine the presence of metastasis. Moreover, if metastasis is confirmed, comprehensive treatment should be combined.