Differentiation between purulent meningitis and viral meningitis

Written by Zhang Hui
Neurology
Updated on September 21, 2024
00:00
00:00

Purulent meningitis and viral meningitis are different diseases. Purulent meningitis is caused by bacterial infection of the meninges. Viral meningitis is caused by viral invasion of the meninges. Generally, purulent meningitis is more severe, and patients may exhibit symptoms of systemic toxin poisoning, such as high fever, nausea, vomiting, sickly appearance, and general weakness. The symptoms of viral meningitis are relatively mild, and the fever is not particularly severe. Another important differentiation is based on the analysis of cerebrospinal fluid. In viral meningitis, the lumbar puncture shows that the white blood cell count is below 1000*10^6/L, and the levels of sugar and chloride are generally normal or slightly low, with protein usually mildly elevated. In purulent meningitis, the cerebrospinal fluid shows a significant increase in white blood cell count, even reaching from 1000*10^6/L to 10000*10^6/L; the protein content is significantly increased, the sugar content is markedly decreased, and chloride levels are reduced. Additionally, bacteria can be found in the cerebrospinal fluid and blood cultures in purulent meningitis, whereas viral meningitis cerebrospinal fluid cultures do not show bacteria.

Other Voices

doctor image
home-news-image
Written by Han Shun Li
Pulmonology
42sec home-news-image

Is meningitis serious?

Meningitis is a common infectious disease of the central nervous system. Patients with meningitis often experience symptoms such as fever, headache, nausea, vomiting, and neck stiffness. As the disease progresses, they may also experience seizures, motor disorders, disturbed consciousness, coma, and other conditions, with severe cases posing a risk to life. Many patients can still have sequelae after recovery, such as speech impairments, hemiplegia, and decreased intelligence. Therefore, meningitis is a very serious disease, and patients should actively cooperate with doctors for treatment after becoming ill.

doctor image
home-news-image
Written by Li Jian Wu
Pulmonology
47sec home-news-image

Causes of Meningitis

The main causes of meningitis are bacteria, viruses, fungi, rickettsiae, or other pathogens, which invade the pia mater, spinal cord, and theca mater, causing infection. Clinically, bacterial meningitis is more severe. If it is not treated promptly or if the treatment is ineffective or misdiagnosed, it may lead to death within a few hours or even cause permanent brain damage, resulting in sequelae. Meningitis can affect the dura mater, arachnoid mater, and pia mater. It may also lead to secondary intracranial infections. It is important to choose antibacterial drugs and medications that nourish brain cells and alleviate cerebral edema for symptomatic treatment promptly.

doctor image
home-news-image
Written by Han Shun Li
Pulmonology
39sec home-news-image

Is meningitis severe?

Meningitis is an infectious inflammation that occurs in the meninges and the brain and spinal meninges, and some may also involve the brain parenchyma. Meningitis is generally a serious disease, and if not treated promptly, it can develop into cerebral edema and severe cases may lead to brain herniation, respiratory and circulatory failure, endangering life. Some patients may even experience a decline in intelligence, paralysis, and other sequelae after recovery, severely affecting the quality of life. Therefore, it is important to actively treat meningitis once contracted.

doctor image
home-news-image
Written by Hu Bai Yu
Pulmonology
58sec home-news-image

Does meningitis cause fever?

Generally, patients with meningitis exhibit symptoms of fever, along with headaches, nausea, vomiting, or some cognitive impairments and confusion. It is advised that everyone should be cautious and distinguish the symptoms of meningitis from those of common colds, and perhaps visit the department of neurology at a hospital for proper diagnosis and targeted treatment. Under the circumstance of meningitis, it is crucial to follow the doctor's guidance and actively cooperate with the treatment. Typically, a regimen involving anti-infection and antiviral medications is necessary for about two to three weeks, and most patients have a favorable prognosis. Additionally, it is important to maintain a relaxed mood, avoid excessive stress, and drink adequate water to promote excretion.

doctor image
home-news-image
Written by Zhang Hui
Neurology
1min 1sec home-news-image

How to rule out meningitis.

Patients with meningitis usually show clinical symptoms such as fever, headache, nausea, and vomiting. To rule out meningitis, the following points should be considered. The first point is to check if the patient has a relevant medical history. If the patient's symptoms are very normal, without fever or headache, the possibility of meningitis is generally not very high. The second point is to pay attention to the physical examination, to see if there is any sign of meningeal irritation. If there is no meningeal irritation, it also does not support the presence of meningitis. The third point involves performing a lumbar puncture to examine the cerebrospinal fluid, checking if the pressure of the cerebrospinal fluid is high, and whether the cellular and biochemical properties within the fluid are normal. If completely normal, the likelihood of meningitis is also very small. Additionally, if necessary, an enhanced MRI scan of the brain should be performed, as meningitis usually shows enhancement.