Precursors of recurrent allergic purpura

Written by Yang Ya Meng
Rheumatology
Updated on November 12, 2024
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The precursors of a relapse of allergic purpura typically occur in patients after exposure to cold, strenuous exercise, or allergens, manifesting as purpuric rash on the skin. Additionally, some patients may experience gastrointestinal reactions such as nausea, vomiting, abdominal pain, and diarrhea. More severe cases can present with symptoms of allergic purpura and purpura nephritis, primarily characterized by edema and significant proteinuria indicated in routine urine tests. If patients experience the aforementioned symptoms, it is crucial to be vigilant about the possibility of a relapse of allergic purpura and to seek medical attention promptly to prevent further progression of the disease.

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Written by Zhou Qi
Nephrology
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Is allergic purpura nephritis contagious?

Henoch-Schönlein purpura nephritis and allergic purpura are not infectious diseases; there is no contagious element involved. Henoch-Schönlein purpura nephritis is actually kidney damage caused by allergic purpura, which is an allergic disease itself. Patients suffer from an abnormal immune response in the body’s immune system after coming into contact with allergenic drugs or foods, leading to necrotizing vasculitis. This disease is unrelated to pathogens. Generally, there is no direct damage to the kidneys caused by a specific pathogen in this disease, nor do patients carry pathogens that can cause Henoch-Schönlein purpura nephritis, such as bacteria or viruses, thus making the disease non-contagious.

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Written by Li Jing
Rheumatology
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Can allergic purpura be cured?

Allergic purpura mainly occurs in adolescents and children, often in the spring and autumn seasons, and is typically related to bacterial infections, viral infections, and allergies to medications and foods. The most common clinical symptoms include bruises on both lower limbs, bleeding, black stools, joint pain, and abdominal pain. Upon the appearance of bruises on the lower limbs, it is recommended to complete routine blood tests, erythrocyte sedimentation rate, and autoantibody tests to rule out other autoimmune diseases causing skin bruises. During the acute phase, it is necessary to rest in bed, drink plenty of water, and eat a light diet. If there are only simple skin bruises, these may resolve after rest. However, if joint pain, bloody stools, and black stools occur, formal and active treatment is required, as these symptoms will not resolve on their own. Additionally, the presence of blood or protein in urine suggests kidney involvement, indicating that the condition has worsened.

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Written by Li Jing
Rheumatology
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What are the symptoms of allergic purpura?

The most common clinical manifestations of allergic purpura are bruises on the limbs, black stool, hematuria, and joint pain. It is mainly divided into articular, abdominal, cutaneous, renal, and mixed types. The presence of protein in the urine indicates kidney involvement, which means the condition is most severe. Allergic purpura generally can be alleviated with standard and active treatment, but recurrent attacks affecting the kidneys can lead to persistent purpuric nephritis and proteinuria that do not resolve.

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Written by Li Jing
Rheumatology
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Precautions for Allergic Purpura

Allergic purpura is a common allergic disorder, also known as vasculitis, and occurs more frequently in adolescent males. Adults can also be affected, but it is less common, and the majority of cases are due to infections, such as bacterial, viral, or parasitic infections. Food or drug allergies are also part of the causes of allergic purpura. For adolescents who develop allergic purpura, infections should be considered first, followed by allergies. It's important to maintain a light diet, drink plenty of water, wear a mask when going out to prevent upper respiratory infections, and control the intake of high-protein foods such as fish, shrimp, eggs, milk, and lean meat. As for fruits, including mangoes, some people can be triggered to have allergic purpura, especially fruits they have not been exposed to before; it's best to minimize contact with unfamiliar fruits to avoid inducing an allergic purpura attack.

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Written by Li Liu Sheng
Nephrology
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Is allergic purpura nephritis contagious?

Kidney damage caused by allergic purpura is called allergic purpuric nephritis. The main mechanism of allergic purpuric nephritis is the deposition of immune complexes in the kidneys, causing hematuria, proteinuria, edema, and hypertension. Severe cases of purpuric nephritis may also lead to renal failure. Additionally, patients with allergic purpuric nephritis exhibit systemic symptoms such as skin purpura, abdominal pain, joint pain, and melena. Allergic purpuric nephritis usually occurs in children, and it is not contagious. Unlike viral hepatitis, tuberculosis, and dysentery, it does not spread through respiratory, digestive, or blood pathways.