Liver cysts that are generally smaller than six centimeters do not require treatment, and surgical treatment of liver cysts is necessary for cysts larger than six centimeters.

The most common surgical method for treating liver cysts is fenestration of the cyst, which involves removing part of the cyst wall. The cyst fluid can then be directly drained into the abdominal cavity through the opening, and as the surgery concludes, the remaining cyst wall adheres and causes the cyst to be completely absorbed.

Another method is percutaneous drainage of the liver cyst, but this method may easily recur; thus, the best current treatment method is still fenestration surgery. Additionally, patients with liver cysts must abstain from alcohol and should not drink alcohol.