Causes of Iron Deficiency Anemia

Written by He Li Fang
Hematology
Updated on September 09, 2024
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There are many reasons for iron deficiency anemia, which we can categorize into several aspects. The first aspect is a decrease in iron intake, including diet, meaning insufficient dietary intake. The second aspect is decreased absorption, such as the absence of a target organ for absorption or the lack of stomach acid affecting its absorption efficacy. The second aspect refers to excessive loss, most commonly chronic gastrointestinal bleeding, such as in patients with tumors, duodenal ulcers, gastric ulcers, gastritis, ulcerative colitis, a parasitic infection with hookworms, as well as hemorrhoids, and arteriovenous malformations, all of which can cause gastrointestinal bleeding leading to increased iron loss. Excessive menstrual flow in female patients, multiple blood donations, and multiple pregnancies can all lead to iron deficiency. These are the various causes related to iron deficiency.

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Written by He Li Fang
Hematology
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What is the fastest way to treat iron deficiency anemia?

Iron deficiency anemia is a type of anemia caused by a lack of storage iron in the body, affecting the synthesis of hemoglobin. It is characterized by a lack of available iron in tissues and organs such as bone marrow, liver, and spleen, with decreased serum iron concentration, transferrin saturation, and serum ferritin levels. Typically, iron deficiency anemia presents as microcytic hypochromic anemia. Iron, as one of the essential trace elements in the human body, is contained in all functioning cells and is broadly involved in metabolic processes within the body. Therefore, the treatment principle for iron deficiency anemia involves replenishing sufficient iron until normal iron stores are restored and addressing the underlying causes that led to the iron deficiency to effectively and quickly replenish iron. Oral iron supplements are the preferred treatment option for iron deficiency anemia, such as ferrous sulfate, ferrous succinate, and iron dextran which are effective oral iron agents.

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Written by He Li Fang
Hematology
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Should I take vitamin C for iron deficiency anemia?

Patients with iron deficiency anemia mostly suffer from anemia due to lack of iron, but in a small proportion of cases, the essence of their anemia is due to the number of red blood cells or hemoglobin per unit volume of blood being below normal levels. Therefore, any factor that can lead to reduced production or excessive destruction, or loss of red blood cells or hemoglobin can cause anemia. Can patients with iron deficiency anemia consume vitamin C? The main treatment plan for iron deficiency anemia includes four aspects. First, general treatment aims to prevent and reduce various factors that induce iron deficiency. Second, etiological treatment involves identifying a cause whenever possible and controlling the primary iron deficiency related to that cause, such as actively combatting hookworm infection in cases of hookworm disease, stopping bleeding and actively treating ulcers in cases of ulcerative bleeding, and actively controlling menstrual flow in women with heavy periods. Third is the supplementation of iron, which should ideally be taken with vitamin C as it can enhance the absorption of iron. Therefore, patients with iron deficiency anemia can indeed consume vitamin C.

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Written by He Li Fang
Hematology
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How long should iron supplements be taken for iron deficiency anemia?

First, it's important to understand that in treating iron deficiency anemia, addressing the underlying cause is the top priority. It's crucial to eliminate the causes of iron deficiency as much as possible. Solely supplementing with iron can only restore the blood picture, and neglecting the treatment of the primary illness will not lead to a thorough treatment of the anemia. Once the medication for anemia is stopped, it can easily relapse. So how long should iron supplements be taken for iron deficiency anemia? Generally, after patients start taking iron supplements, they can quickly feel an improvement in symptoms. The reticulocyte count tends to rise within three to four days after starting the supplements, reaching a peak around seven days. Hemoglobin shows a significant increase two weeks after starting the medication and can return to normal levels within one to two months. However, even after hemoglobin returns to normal, iron treatment should continue until the serum ferritin level has returned to 50 micrograms per liter before stopping the medication. If it's not possible to monitor serum ferritin, then iron supplements should be continued for three more months after hemoglobin has normalized, to replenish the body's iron stores. Therefore, the treatment of iron deficiency anemia with iron supplements generally lasts for three to six months.

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Written by Li Guo Bao
Hematology
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Can iron deficiency anemia be cured?

Iron deficiency anemia is one of the most common types of anemia clinically. The principle of treating iron deficiency anemia involves etiological treatment and symptomatic treatment. Etiological treatment means treating according to different causes, while symptomatic treatment involves correcting anemia and supplementing the raw materials for blood formation. The most common causes of iron deficiency anemia include gastrointestinal bleeding, internal hemorrhoids bleeding, hookworm and roundworm infections, malnutrition, and, notably in women, excessive menstrual bleeding and excessive bleeding during pregnancy and childbirth. These are common causes of iron deficiency anemia seen clinically. With the cause of iron deficiency anemia identified, the treatment often has a relatively high cure rate.

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Written by He Li Fang
Hematology
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The key to curing iron deficiency anemia

Iron deficiency anemia, a common and frequently occurring disease in the department of hematology, is not difficult to diagnose and treat. The key to treatment lies in addressing the cause of the iron deficiency, and it is essential to eliminate the underlying causes as much as possible. Using iron supplements alone can only restore blood counts; neglecting the primary disease will not lead to a complete cure of the anemia and can easily lead to recurrence. Treatment consists of two phases: first, the supplementation with iron supplements. After taking iron supplements for three to four days, an increase in reticulocytes will occur, reaching a peak around seven days, and hemoglobin will significantly rise after two weeks of medication, returning to normal levels after one to two months. However, after hemoglobin levels normalize, some patients may stop taking the medication. It is important to note that continuing to take iron supplements for three months is necessary to replenish the body's iron stores completely.