Characteristics of iron deficiency anemia blood picture

Written by He Li Fang
Hematology
Updated on September 12, 2024
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The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.

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Written by He Li Fang
Hematology
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Iron deficiency anemia clinical symptoms

The clinical manifestations of iron deficiency anemia include symptoms caused by ischemia-induced tissue and organ hypoxia, as well as specific clinical signs associated with iron deficiency. Common clinical manifestations of iron deficiency anemia often include dizziness, headache, fatigue, easy tiring, memory decline, shortness of breath and palpitations after activities, and even symptoms such as tinnitus and blurred vision. Specific signs of iron deficiency include stomatitis, glossitis, atrophic gastritis, dry skin, brittle and falling hair, flat or spoon-shaped nails that are thin and prone to cracking. Some patients may also experience pica and difficulty swallowing, all of which are clinical manifestations of iron deficiency anemia.

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Written by Zhang Xiao Le
Hematology
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Hazards of Iron Deficiency Anemia in Women

The harm of iron deficiency anemia in women is related to the severity of the anemia. Mild anemia generally has no obvious clinical symptoms; moderate anemia often presents with fatigue, palpitations and shortness of breath after activity, dizziness, tinnitus, insomnia, frequent dreams, reduced appetite, and poor digestive function; severe anemia can affect the quality of life, with symptoms of palpitations and shortness of breath even with slight activity, and can severely impact the quality of life. The most common cause of iron deficiency anemia in women is due to increased menstrual flow. Additional examinations, such as gynecological ultrasound, are necessary to clarify the presence of conditions like uterine fibroids or adenomyosis, and to provide targeted treatment.

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Written by He Li Fang
Hematology
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Causes of Iron Deficiency Anemia

There are many reasons for iron deficiency anemia, which we can categorize into several aspects. The first aspect is a decrease in iron intake, including diet, meaning insufficient dietary intake. The second aspect is decreased absorption, such as the absence of a target organ for absorption or the lack of stomach acid affecting its absorption efficacy. The second aspect refers to excessive loss, most commonly chronic gastrointestinal bleeding, such as in patients with tumors, duodenal ulcers, gastric ulcers, gastritis, ulcerative colitis, a parasitic infection with hookworms, as well as hemorrhoids, and arteriovenous malformations, all of which can cause gastrointestinal bleeding leading to increased iron loss. Excessive menstrual flow in female patients, multiple blood donations, and multiple pregnancies can all lead to iron deficiency. These are the various causes related to iron deficiency.

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Written by He Li Fang
Hematology
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Iron deficiency anemia should see which department?

Anemia is a condition characterized by a reduction in the total volume of red blood cells in the circulating blood to below normal levels. Iron deficiency anemia is a type of anemia caused by a lack of raw materials for blood production. Iron deficiency anemia occurs when the body's stored iron is depleted and cannot meet the needs for normal red blood cell production. Iron deficiency anemia is a common type of red blood cell disease and falls within the category of hematology. Therefore, patients with iron deficiency anemia should seek treatment in the department of hematology.

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Written by He Li Fang
Hematology
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Symptoms of iron deficiency anemia

The clinical manifestations of iron deficiency anemia consist of symptoms due to the anemia itself, specific manifestations of iron deficiency, and the underlying diseases causing the iron deficiency. The onset of anemia is often insidious, with some patients progressing very slowly. Initially, patients can adapt well to daily life and continue with their work, making it difficult to detect. It is usually not until the anemia becomes moderate to severe and symptoms become apparent that it is discovered. Common symptoms of anemia include dizziness, headaches, weakness, easy fatigue, palpitations, and shortness of breath after activity. Some patients might also experience a decline in memory and suffer from tinnitus and blurred vision. Some affected children may exhibit delayed growth and development or even abnormal behaviors, which can manifest as irritability, restlessness, inattention in class, and declining academic performance. A few patients may develop pica, a specific manifestation of iron deficiency anemia. Additionally, some patients might suffer from angular cheilitis, glossitis, and even atrophy of the tongue papillae. Severe cases can experience transient blindness and fainting, hence it is crucial to seek medical attention for iron deficiency anemia at the earliest.