Characteristics of iron deficiency anemia blood picture

Written by He Li Fang
Hematology
Updated on September 12, 2024
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The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.

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Written by Zhang Xiao Le
Hematology
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Hazards of Iron Deficiency Anemia in Women

The harm of iron deficiency anemia in women is related to the severity of the anemia. Mild anemia generally has no obvious clinical symptoms; moderate anemia often presents with fatigue, palpitations and shortness of breath after activity, dizziness, tinnitus, insomnia, frequent dreams, reduced appetite, and poor digestive function; severe anemia can affect the quality of life, with symptoms of palpitations and shortness of breath even with slight activity, and can severely impact the quality of life. The most common cause of iron deficiency anemia in women is due to increased menstrual flow. Additional examinations, such as gynecological ultrasound, are necessary to clarify the presence of conditions like uterine fibroids or adenomyosis, and to provide targeted treatment.

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Written by Li Fang Fang
Hematology
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Can iron deficiency anemia be cured?

Iron deficiency anemia is treatable, but it is essential to identify the cause of the iron deficiency. The treatment of iron deficiency anemia is divided into two main parts. The first part involves iron supplementation, which can be administered orally or intravenously, with intravenous supplementation generally being more effective and faster. The second part is crucial: identifying the cause of the iron deficiency. For example, common causes in women of childbearing age include heavy menstrual periods, while older patients often suffer from gastrointestinal tumors or ulcers, and in children, the common cause is usually nutritional deficiency. It is vital to treat the underlying cause.

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Written by He Li Fang
Hematology
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Iron deficiency anemia lacks iron.

Iron deficiency anemia is an anemia caused by the lack of stored iron in the body, affecting the synthesis of hemoglobin. It is characterized by a lack of stainable iron in the bone marrow, liver, spleen, and other organ tissues, as well as decreased serum iron concentration, transferrin saturation, and ferritin levels, typically presenting as microcytic hypochromic anemia. Thus, iron deficiency anemia refers to a deficiency of iron. Iron is an essential trace element in the human body, involved in cellular functions and metabolic processes. The body has a strict regulatory mechanism for iron metabolism to ensure that iron levels are always maintained at a normal level, referred to as iron homeostasis. Iron homeostasis relies crucially on the balance between intestinal iron absorption and the body's iron requirements. Once this balance is disrupted, problems in iron distribution, absorption, transport, and storage may occur, leading to iron deficiency anemia.

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Written by He Li Fang
Hematology
1min 26sec home-news-image

Characteristics of iron deficiency anemia blood picture

The clinical manifestations of iron deficiency anemia are due to the specific characteristics of anemia caused by iron deficiency and the underlying disease causing the iron deficiency. Its hematological characteristics present as typical microcytic hypochromic anemia. What does this concept mean? It refers to the values in a complete blood count where MCV is less than 80 femtoliters, MCH is less than 27 picograms, and MCHC is less than 30%. MCV refers to the average red blood cell volume, MCH refers to the mean corpuscular hemoglobin concentration, and MCHC refers to the mean corpuscular hemoglobin concentration of red blood cells. The extent of changes in red blood cell indices correlates with the duration and severity of anemia. The blood smear typically shows pale-stained red blood cells with an enlarged central pallor and varying sizes. Platelet count often tends to be high when there is concurrent bleeding and generally tends to be low in infants and children. White blood cell count is usually normal or slightly reduced, with normal differential. These are the hematological characteristics of iron deficiency anemia.

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Written by He Li Fang
Hematology
1min 9sec home-news-image

How long does iron deficiency anemia need to be treated?

Patients with iron deficiency anemia typically need several months of iron supplementation treatment. The specific reason is that after taking iron supplements, patients' subjective symptoms can recover quickly. The count of reticulocytes generally begins to rise within three to four days after starting the medication, reaching a peak around seven days. Hemoglobin levels notably increase within two weeks of treatment, and generally return to normal around two months. After correcting anemia, it is necessary to continue treatment for at least another three months because the body's iron stores need further supplementation. It is necessary to restore serum ferritin levels to fifty micrograms per liter to replenish these stores fully. This is required to achieve a true cure of iron deficiency anemia, as without this, patients are prone to relapse. Therefore, regular and long-term effective use of iron supplements is an essential basis for ensuring the treatment effectiveness of iron deficiency anemia.