Is vulvar leukoplakia cancer?

Written by Li Li Jie
Obstetrics and Gynecology
Updated on September 16, 2024
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First, vulvar lichen sclerosus is not cancerous. Vulvar lichen sclerosus is a general term that can be divided into many types, and the cause of the disease is unknown. The main symptoms include itching, atrophy, and whitening of the vulva. Because of vulvar itching, long-term scratching can lead to local skin thickening, cracking, and a certain risk of cell degeneration and malignancy. When vulvar lichen sclerosus occurs, patients need to visit a hospital for a colposcopy to rule out precancerous lesions. The usual treatment focuses on symptomatic relief, primarily to alleviate itching. If the itching is severe or if the treatment with medication is ineffective, photodynamic therapy can be used, which also has good effects.

Other Voices

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Written by Yan Chun
Oncology
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What tests are needed to determine the cause of vulvar cancer?

Vulvar cancer is a type of malignant tumor in female gynecology. Clinically, the following examinations can be used to identify the cause of vulvar cancer. First, testing for human papillomavirus (HPV) can be conducted. If the patient is found to be infected with HPV, then the cause of vulvar cancer can be considered to be due to viral infection. Additionally, herpes virus testing can also be performed, as many patients with vulvar cancer are caused by herpes virus infection. Thirdly, cytological examination of the vulva can be conducted to detect if there are any malnutritive lesions, such as vulvar lichen sclerosus, and other diseases like dermatophytosis, which are also reasons for the high incidence of vulvar cancer.

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Written by Sun Ming Yue
Medical Oncology
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Late-stage vulvar cancer can spread to where?

Patients with vulvar cancer generally have lymphatic metastasis because there are many lymphatic vessels in the perineum, and the capillaries of the lymphatic system are interconnected. Thus, vulvar cancer can lead to bilateral lymphatic vessel spread. Initially, it leads to superficial inguinal lymph nodes, then it spreads to the bone lymph nodes below the groin, and eventually progresses to the lymph nodes alongside the aorta and the lymph nodes below the left clavicle. If the cancer is located in the clitoris, it may bypass the superficial inguinal lymph nodes and directly spread to the lymph nodes inside the pelvis. The tumor in the vulvar area will gradually increase in size; it generally does not invade the muscle fascia or adjacent structures. If the vagina is invaded, it can easily and immediately involve the levator ani muscles, rectum, urethral opening, and bladder, among others.

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Written by Yan Chun
Oncology
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Is the vulvar cancer nodule soft or hard?

Vulvar cancer clinically forms nodular lesions that are generally hard in texture with poor mobility and tend to adhere to surrounding tissues, and have indistinct borders. Due to the rapid growth of the nodules, their shape is usually irregular, easily forming granulomatous or cauliflower-like appearances, and they are prone to contact bleeding. Patients with vulvar cancer typically have nodular lesions that are likely to invade surrounding tissues or metastasize to lymph nodes. The chances of distant metastasis to the lungs, liver, bones, or brain are relatively lower. Clinically, it is common to see enlarged inguinal lymph nodes and pain caused by metastatic foci. Some patients may also experience local skin metastasis, subcutaneous nodules, or skin itching as clinical manifestations. For the treatment of vulvar cancer, radical surgery is primarily recommended, with radiation therapy and chemotherapy also being effective options.

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Written by Yan Chun
Oncology
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Is vulvar cancer stage III considered advanced?

Vulvar cancer is a type of malignant tumor in women's gynecology, which has a relatively low clinical incidence rate. For stage III vulvar cancer, it is considered advanced vulvar cancer. Advanced vulvar cancer indicates that the lesion has spread. For vulvar cancer with lesion spread, surgical treatment should be pursued if possible. For patients who cannot undergo surgery, options like chemotherapy, radiotherapy, targeted therapy, and other comprehensive combined treatment methods can be considered for cancer treatment. However, for patients with advanced vulvar cancer, the aim of treatment is mainly to improve the quality of life and extend the survival time, as complete clinical cure of the tumor is not possible. Only early-stage vulvar cancer, after receiving curative surgery or curative radiotherapy, may achieve a clinically cured effect.

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Written by Yan Chun
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What will happen when vulvar cancer becomes severe?

Vulvar cancer is a malignant tumor of the female reproductive system. When vulvar cancer becomes severe, the lesions metastasize to many areas, which can cause serious clinical symptoms, severely affect the patient's quality of life, and even endanger the patient's life. For example, if vulvar cancer metastasizes to the inguinal lymph nodes, pain can occur in the area of the metastases. Additionally, mobility of the limb on the side of the metastases is limited, and swelling of the lower limb occurs. If the patient's lesions metastasize to the lungs through the hematogenous route, clinically the patient may experience coughing, expectoration, chest tightness, chest pain, and even some patients may have respiratory failure, which severely threatens their life. Some patients have bone metastases, and besides pain in the area of the bone metastases, some patients also experience pathological fractures, limited mobility, and significant pain.