Vulvar cancer lymph node metastasis is stage III.

Written by Yan Chun
Oncology
Updated on September 25, 2024
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Vulvar cancer is a type of malignant tumor in the female reproductive system, commonly occurring in postmenopausal elderly women. The disease progresses to involve lymph node metastasis, and its clinical staging is either stage III or stage IV. If the disease spreads to the inguinal lymph nodes with no other site affected, then the clinical stage is considered stage III. If the vulvar cancer metastasizes to the pelvic lymph nodes, or distant locations such as the liver, lungs, or bones, then it is classified as stage IV. For cases of stage III and IV vulvar cancer, the main treatment methods are palliative surgery, radiation therapy, and chemotherapy. The treatment strategy primarily involves a combination of surgery and radiation therapy along with chemotherapy. For patients with stage III and IV vulvar cancer, the prognosis is generally poor.

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Is vulvar leukoplakia cancer?

First, vulvar lichen sclerosus is not cancerous. Vulvar lichen sclerosus is a general term that can be divided into many types, and the cause of the disease is unknown. The main symptoms include itching, atrophy, and whitening of the vulva. Because of vulvar itching, long-term scratching can lead to local skin thickening, cracking, and a certain risk of cell degeneration and malignancy. When vulvar lichen sclerosus occurs, patients need to visit a hospital for a colposcopy to rule out precancerous lesions. The usual treatment focuses on symptomatic relief, primarily to alleviate itching. If the itching is severe or if the treatment with medication is ineffective, photodynamic therapy can be used, which also has good effects.

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Written by Sun Ming Yue
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Can vulvar cancer be detected by TCT?

The patient's TCT generally cannot detect whether they have vulvar cancer. TCT can also be referred to as liquid-based thin layer cytology, primarily examining the exfoliated cells scraped from the cervix to see if they are malignant. A negative result indicates that there is no cervical cancer. If one wishes to check for vulvar cancer, gynecological examinations can be conducted. These include blood tests for tumor markers, vaginal ultrasound, and vaginal tissue biopsy. Through these tests, any abnormalities in the vulva can be detected. It is advised that patients seek timely examination and treatment based on the disease.

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Written by Yan Chun
Oncology
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Will the vulvar cancer be rotten in the late stage?

Patients with advanced vulvar cancer do not all show signs of internal ulceration. This is because, for most patients with vulvar cancer, the progression of the disease can lead to invasion of the surrounding tissues or distant metastasis. Some patients may experience heavy local infiltration, leading to tissue ulceration. However, most patients in the advanced stages primarily show symptoms related to lymphatic and hematogenous metastasis. When patients with advanced vulvar cancer develop lymph node metastasis and distant metastasis, they may experience symptoms of metastatic lesions, such as inguinal lymph node metastasis causing limb swelling and pain. If there are distant metastases to the lungs, liver, or other areas, patients may exhibit respiratory symptoms such as coughing and expectoration, or liver-related symptoms such as pain in the liver area or decreased appetite.

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Written by Sun Ming Yue
Medical Oncology
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Late-stage vulvar cancer can spread to where?

Patients with vulvar cancer generally have lymphatic metastasis because there are many lymphatic vessels in the perineum, and the capillaries of the lymphatic system are interconnected. Thus, vulvar cancer can lead to bilateral lymphatic vessel spread. Initially, it leads to superficial inguinal lymph nodes, then it spreads to the bone lymph nodes below the groin, and eventually progresses to the lymph nodes alongside the aorta and the lymph nodes below the left clavicle. If the cancer is located in the clitoris, it may bypass the superficial inguinal lymph nodes and directly spread to the lymph nodes inside the pelvis. The tumor in the vulvar area will gradually increase in size; it generally does not invade the muscle fascia or adjacent structures. If the vagina is invaded, it can easily and immediately involve the levator ani muscles, rectum, urethral opening, and bladder, among others.

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Does vulvar cancer spread quickly if not treated with chemotherapy?

Vulvar cancer is a type of malignant tumor in women. For patients in the early stages of vulvar cancer, chemotherapy is generally not required after radical surgery. Even without chemotherapy, the disease progression of early-stage vulvar cancer is relatively slow, and many patients can achieve clinical cure after the radical surgery. However, for patients with mid-to-late stage vulvar cancer, postoperative adjuvant chemotherapy is generally required after the radical surgery to reduce the chances of disease recurrence and metastasis. Without postoperative adjuvant chemotherapy, the disease can spread quickly, and many patients soon experience the spread of the disease, eventually leading to multi-organ failure and death. Therefore, it is essential for patients who need adjuvant chemotherapy to complete the supplementary treatment regularly and on time after surgery.