Peptic ulcer is a common disease of the upper gastrointestinal tract, including gastric ulcer, duodenal bulb ulcer, and gastroduodenal complex ulcer, etc. The primary cause is often infection with Helicobacter pylori. Other factors, such as poor dietary habits, smoking and alcohol stimulants, drug irritants, or emotional factors, can also lead to peptic ulcers. As for the severity of peptic ulcers, it should be judged based on the patient's age, medical history, medication history, and the results of gastroscopy, among other factors. Generally, peptic ulcers are not serious and can be cured with medication. However, a minority of recurrent cases might have a tendency to become cancerous. These cases can be effectively treated with a combination of medical and surgical treatments, and are generally not severe.