Peptic ulcer clinical symptoms

Written by Jiang Guo Ming
Gastroenterology
Updated on September 16, 2024
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Helicobacter pylori infection is considered the primary cause of peptic ulcers, often leading to excess stomach acid, abnormal gastric motility, and other symptoms. Excess stomach acid can cause acid reflux, heartburn, and a burning sensation, while abnormal gastric motility may lead to nausea, belching, and even vomiting and bloating, with stomach acid irritation likely causing upper abdominal pain. Gastric ulcer pain is generally located in the upper left abdomen or below the sternum, typically presenting as postprandial pain. Duodenal bulb ulcers generally cause pain to the upper right of the navel, typically fasting pain that eases upon eating, sometimes accompanied by menstrual-like pain, with pain from ulcers behind the bulb potentially radiating to the back.

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Written by Zhu Dan Hua
Gastroenterology
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Can peptic ulcers become cancerous?

Peptic ulcers generally refer to gastric ulcers and duodenal ulcers. It is generally believed that most gastric ulcers are benign, but a small portion of patients may develop cancer, approximately 3%-5%, especially in middle-aged and elderly patients. If the ulcers recur and continue to enlarge, there needs to be vigilance for potential malignancy. However, duodenal ulcers generally do not become cancerous and are more common in young people, presenting symptoms such as abdominal pain, bloating, and bloody stools. Therefore, for peptic ulcers, most are benign, but a small fraction of patients may have ulcers that evolve into cancerous ones, presenting as benign peptic ulcers, which calls for caution, especially in middle-aged and elderly patients. Therefore, it is recommended that patients regularly treat gastric and duodenal ulcers. If the treatment period is prolonged and peptic ulcers recur frequently with poor outcomes, patients should be alert to the potential for cancer and are advised to undergo gastroscopic examination and biopsy for further clarification.

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Written by Jiang Guo Ming
Gastroenterology
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The main symptoms of peptic ulcers

Common types of peptic ulcers, including gastric ulcers, duodenal bulb ulcers, complex ulcers, and anastomotic ulcers after gastric resection, share common characteristics and have their own distinct symptoms. Abdominal pain is a usual symptom. The pain from duodenal bulb ulcers tends to be dull, bloating, or blunt, and it is generally more noticeable when hungry. The pain often eases after eating as food neutralizes stomach acid. Sometimes, there is pain at night. If the ulcer is beyond the bulb or is a penetrating ulcer, it often comes with back pain; gastric ulcers primarily manifest as postprandial pain, meaning pain occurring half an hour to an hour after eating, which gradually alleviates; complex ulcers often present with both types of symptoms mentioned above. As peptic ulcers are often associated with excessive stomach acid, symptoms like acid reflux, heartburn, and nausea are common.

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Written by Jiang Guo Ming
Gastroenterology
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Clinical characteristics of peptic ulcer

The main cause of peptic ulcers is believed to be infection by Helicobacter pylori. Other factors such as smoking, alcohol, poor diet, living habits, medication use, or emotional issues can also play a role. Clinically, these ulcers are often characterized by upper abdominal pain. In the case of gastric ulcers, the pain is primarily in the upper left abdomen or below the sternum, and can manifest as dull pain, blunt pain, or a feeling of distension. This pain is often more apparent after meals, commonly occurring half an hour to an hour after eating, and usually subsides two to three hours later. Duodenal bulb ulcers are characterized by upper abdominal muscular pain, occurring around two centimeters above and to the right of the navel, sometimes accompanied by nighttime pain. If the ulcer is located behind the bulb, back pain can also occur. Peptic ulcers can lead to other complications, such as perforation, bleeding, or even cancer.

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Written by Jiang Guo Ming
Gastroenterology
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Can people with peptic ulcers exercise?

The primary cause of peptic ulcers is usually Helicobacter pylori infection, though other factors can also trigger the onset of peptic ulcers, such as tobacco and alcohol irritation, poor dietary habits, and emotional issues. Additionally, excessive fatigue is also one of the causes that can trigger or cause a recurrence of peptic ulcers. Therefore, whether or not a person with peptic ulcers can exercise depends on the specific condition of the illness. If it is an acute active phase or a subacute peptic ulcer that has not fully healed, strict rest is necessary in such cases. If a gastroscopy shows that the ulcer has completely healed, moderate and light activities are permissible, but excessive fatigue should still be avoided.

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Written by Ren Zheng Xin
Gastroenterology
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The difference between peptic ulcer and gastric ulcer.

Peptic ulcers refer to ulcers occurring in the digestive tract, including duodenal ulcers and gastric ulcers, whereas gastric ulcers specifically refer to ulcerative lesions occurring in the gastric mucosa. Clinically, there is often a distinction made between duodenal ulcers and gastric ulcers. Clinically, gastric ulcers cause postprandial pain, while duodenal ulcers are characterized by midnight pain and hunger pain. Additionally, the locations of occurrence differ; gastric ulcers commonly occur on the lesser curvature of the stomach, whereas duodenal ulcers commonly occur in the bulb. The treatment methods are fundamentally similar, primarily involving the use of medications that inhibit gastric acid secretion and protect the mucous membrane. Moreover, it involves enhancing health education, maintaining a regular diet, reasonable rest, and avoiding excessive fatigue. (Please use medication under the guidance of a physician.)