Peptic ulcer clinical symptoms

Written by Jiang Guo Ming
Gastroenterology
Updated on September 16, 2024
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Helicobacter pylori infection is considered the primary cause of peptic ulcers, often leading to excess stomach acid, abnormal gastric motility, and other symptoms. Excess stomach acid can cause acid reflux, heartburn, and a burning sensation, while abnormal gastric motility may lead to nausea, belching, and even vomiting and bloating, with stomach acid irritation likely causing upper abdominal pain. Gastric ulcer pain is generally located in the upper left abdomen or below the sternum, typically presenting as postprandial pain. Duodenal bulb ulcers generally cause pain to the upper right of the navel, typically fasting pain that eases upon eating, sometimes accompanied by menstrual-like pain, with pain from ulcers behind the bulb potentially radiating to the back.

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Written by Jiang Guo Ming
Gastroenterology
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How to treat peptic ulcers?

The treatment of peptic ulcers should be based on specific causes, as well as the patient's gender, age, medical history, and medication history, among other factors. Generally speaking, the primary cause of peptic ulcers is usually Helicobacter pylori infection. Therefore, the first step is to test for Helicobacter pylori. If Helicobacter pylori is present, antibacterial treatment is required, with the first choice being quadruple therapy, which includes a proton pump inhibitor, two types of antibiotics, and a bismuth agent, administered over a 10 to 14-day treatment course. If there is no Helicobacter pylori infection, the first choice would be proton pump inhibitors and gastric mucosal protective drugs, combined with symptomatic treatment. Meanwhile, it is crucial for patients with peptic ulcers to develop good eating and living habits, and relaxing their mindset can also be helpful.

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Written by Jiang Guo Ming
Gastroenterology
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Can peptic ulcers be cured?

Peptic ulcers include gastric ulcers, duodenal bulb ulcers, complex ulcers, and more. The primary cause is usually Helicobacter pylori infection, particularly in patients with duodenal bulb ulcers. Generally, eradicating Helicobacter pylori can cure the ulcer. However, a small number of patients, due to underlying diseases or irregular medication use, often develop resistance to Helicobacter pylori. In such cases, peptic ulcers are prone to recurrent flares. Additionally, peptic ulcers caused by other factors, such as smoking and alcohol stimulation, poor dietary habits, medication, emotional issues, etc., can generally be cured by removing the triggers. However, it's essential to develop good dietary and living habits and strictly follow medical advice regarding medications.

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Written by Jiang Guo Ming
Gastroenterology
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What can people with peptic ulcers eat?

Peptic ulcers include duodenal bulb ulcers, gastric ulcers, complex ulcers, etc. In such cases, formal treatment should be administered first. Depending on whether there is a Helicobacter pylori infection, different treatment plans should be adopted. At the same time, it is important to develop good dietary and living habits, quit smoking and drinking, and ensure that the diet is light and easy to digest. While ensuring adequate nutrition, efforts should be made to minimize gastric irritation. Foods like soft and mushy rice, porridge, and soft noodles are preferable. Fresh vegetables and fruits are fine. Try to avoid overly cold, greasy, spicy, or irritating foods. Be sure to eat regularly and in moderation or have small, frequent meals, and avoid binge eating.

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Written by Zhu Dan Hua
Gastroenterology
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Peptic Ulcer Clinical Symptoms

Peptic ulcers are a common disease and often seen in clinical practice. They are typically manifested by discomfort in the upper abdomen, which may include abdominal pain, bloating, nausea, vomiting, and belching, and patients usually visit the gastroenterology department. The abdominal pain related to peptic ulcers, particularly the most typical and common symptoms, usually presents as pain above the navel, with chronic and recurrent attacks. It often relates to dietary habits, such as postprandial worsening in the case of gastric ulcers, whereas duodenal ulcers typically improve after eating and may involve hunger pain and night pain. Therefore, if patients exhibit these typical symptoms, it is recommended to perform a gastroscopy to ascertain the presence of duodenal or gastric ulcers. Complications can occur with peptic ulcers, with the most common being gastrointestinal bleeding, manifested by vomiting blood or bloody stools, with the latter appearing as tarry, watery stools. Thus, if patients present with typical symptoms of abdominal pain, bloating, and particularly bleeding or vomiting blood and bloody stools, peptic ulcers are the most likely cause. It is advised for patients to actively seek treatment at local hospitals and receive medication therapy.

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Written by Jiang Guo Ming
Gastroenterology
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Causes of Peptic Ulcers

Peptic ulcers, which include gastric ulcers, duodenal bulb ulcers, complex ulcers, and anastomotic ulcers following gastric surgery, are among the common gastrointestinal diseases. It is currently believed that the infection of Helicobacter pylori is closely associated with gastritis, ulcer activity, gastric cancer, etc., thus, Helicobacter pylori infection is considered the main cause of gastric ulcers. Other factors, such as excessive smoking and alcohol consumption, can also lead to peptic ulcers. Poor dietary and living habits, such as binge eating, excessive consumption of cold, greasy, spicy, or alcoholic foods, can cause this condition as well; moreover, excessive emotional stress, such as long-term mental pressure, can also lead to the development of peptic ulcers.