What will happen if patent ductus arteriosus is not treated with surgery?

Written by Xie Zhi Hong
Cardiology
Updated on December 24, 2024
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Patients with patent ductus arteriosus are characterized by a congenital connection between the pulmonary artery and the aortic arch. This is a remnant passageway that was used during embryonic development to supply blood within the umbilical vessels, ensuring the development of the infant. Normally, this ductus arteriosus may close on its own within a few months. If it does not close after one year from birth, it is considered a patent ductus arteriosus. This condition can lead to increased workload on the heart. Because it allows blood pumped into the aorta to return to the right ventricle, over time, this can increase the burden on the left ventricle as well as the right ventricle. This may lead to heart failure and, in severe cases, trigger Eisenmenger's syndrome. If this condition reaches such a state, the patient loses the opportunity for surgery, resulting in a shortened lifespan.

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Written by Di Zhi Yong
Cardiology
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Will patent ductus arteriosus increase with age?

Patent ductus arteriosus is a type of congenital heart disease, primarily treated through surgery. Early surgical intervention can completely cure this disease. However, as age increases, the symptoms of this disease can become more severe. Based on the patient's condition, it is recommended to undergo early surgical treatment at a hospital to alleviate the patient's suffering. As age increases, various organic diseases may emerge, which can sometimes affect a child's growth and development. During this period, it is advised that the patient regularly revisits the hospital for echocardiography checks and to also be cautious in preventing upper respiratory infections.

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Written by Xie Zhi Hong
Cardiology
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Will patent ductus arteriosus show signs of peripheral vascular disease?

Peripheral vascular signs refer to a medical sign characterized by enhanced pulsation of the peripheral arteries and capillaries due to increased pulse pressure. Patients with a patent ductus arteriosus can experience increased pulse pressure, leading to rapid rises and falls in pressure within the peripheral vessels, thereby causing a series of peripheral vascular signs. When a patent ductus arteriosus is combined with peripheral vascular signs, indicating a substantial shunt, it is advisable for such individuals to undergo surgery as soon as possible. Delaying surgery may lead to a right-to-left shunt, resulting in Eisenmenger's syndrome, and the loss of the opportunity for surgical intervention.

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Written by Jia Qiu Ju
Cardiology
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Can patent ductus arteriosus cause shortness of breath?

Patent ductus arteriosus can indeed cause shortness of breath. Patent ductus arteriosus refers to a duct between the aorta and the pulmonary artery that fails to close after birth. This can cause blood from the aorta to shunt into the pulmonary artery, leading to high pressure in the pulmonary artery and causing pulmonary congestion, which can lead to pulmonary edema and symptoms such as difficulty breathing. Therefore, if the pulmonary hypertension is not severe, there might still be an opportunity for surgery. Once patent ductus arteriosus is diagnosed and if the timing is appropriate, it is recommended to perform occlusion or surgical treatment as soon as possible to prevent pulmonary hypertension and potentially inducing heart enlargement, which may trigger heart failure.

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Written by Tang Li
Cardiology
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What are the symptoms of patent ductus arteriosus?

Patients with patent ductus arteriosus may exhibit several clinical manifestations based on the amount of shunting. 1. Small shunt volume: The internal diameter of the patent ductus arteriosus is small, and the patient may exhibit no subjective symptoms. The prominent sign is a continuous machinery murmur heard at the left sternal border at the second intercostal space and below the left clavicle, accompanied by a thrill; pulse pressure may slightly increase. 2. Moderate shunt: Patients commonly experience fatigue, palpitations, shortness of breath, and chest discomfort after exertion. The heart murmur is similar in character to the above but louder, accompanied by a thrill, and widely transmitted. At times, diastolic and mild systolic murmurs caused by left ventricular enlargement, relative mitral valve insufficiency, and stenosis can be heard at the apex, with a positive vascular sign. 3. Large shunt volume: This condition in a patent ductus arteriosus often accompanies secondary severe pulmonary hypertension, leading to a right-to-left shunt. The typical murmur's diastolic component may diminish or disappear, followed by the disappearance of the systolic murmur, and only a diastolic murmur due to pulmonic valve insufficiency can be heard. Patients often exhibit cyanosis and severe clinical symptoms.

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Written by Cai Li E
Cardiology
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Can you run with a patent ductus arteriosus?

Patients with patent ductus arteriosus should avoid running. The condition can cause a left-to-right shunt, increasing pulmonary circulation and the volume of blood returning to the left heart system, which in turn leads to increased left heart workload and potential left heart dysfunction. In adults with patent ductus arteriosus, the clinical symptoms vary depending on the size of the shunt. Those with very small shunts may exhibit no subjective symptoms clinically. Patients with moderate shunts often experience symptoms such as fatigue, palpitations after activity, shortness of breath, and chest tightness. Those with large shunts, often accompanied by severe secondary pulmonary hypertension, may experience a right-to-left shunt, leading to cyanosis and very severe clinical symptoms.