Causes of Lung Cancer

Written by Hu Zhong Dong
Medical Oncology
Updated on October 31, 2024
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The most common cause of lung cancer is smoking, but many people who have never smoked also develop lung cancer. One possible reason could be related to kitchen fumes. Chinese cooking habits often involve high-temperature frying and stir-frying. After frying in hot oil, the higher the temperature, the more harmful substances are in the fumes, which over time could lead to lung cancer. Some patients develop lung cancer due to air pollution; secondhand smoke is also a significant cause. For example, if a husband smokes, the likelihood of his wife developing lung cancer is more than 200% higher than in the general population, indicating that smoking harms not only the smoker but also their nearest and dearest family members. Additionally, there are other potential causes including psychosomatic factors such as chronic insomnia, depression, decreased immunity, genetic factors, and more.

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What causes lung cancer?

Lung cancer is caused by a variety of factors. Research indicates that lung cancer results from a combination of genetic defects, external and internal environmental factors, and personal factors. Numerous studies have confirmed that long-term and heavy smoking is the most significant carcinogenic factor for lung cancer. There is a positive correlation between the amount and duration of smoking and the incidence of lung cancer. The second factor is related to working in asbestos-related industries, which very much relates to the work environment, and also has a certain relation to smog. Indoor environmental pollution is also a very significant carcinogenic factor for lung cancer. This includes smoke from burning coal indoors, fumes from cooking oils in kitchens, and carcinogenic substances released by indoor decorating materials. Fourthly, internal human factors such as the immune status, metabolic abnormalities, genetic factors, and chronic lung infections are also related. The fifth factor involves irregular diet and rest habits, irritating foods, alcohol consumption, and heavy smoking.

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How is lung cancer caused?

The specific causes of lung cancer are not completely clear, but there are some high-risk factors. Research has shown that lung cancer is influenced by a combination of genetic defects and internal and external environmental carcinogens. It is undeniable that long-term heavy smoking is the most important carcinogenic factor for lung cancer, with the amount and duration of smoking being positively correlated with the incidence of lung cancer. Secondly, environmental factors, such as working with asbestos or in mining areas, are also very relevant to the incidence of lung cancer. Thirdly, irregular eating habits, rest, alcohol consumption, indoor combustion, coal smoke, fumes from kitchen cooking, and carcinogenic substances released from indoor decorations and materials are also related. Fourthly, the body's internal immune status, metabolic abnormalities, genetic factors, and chronic lung infections also have a significant impact.

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How is lung cancer diagnosed?

Lung cancer is one of the malignant tumors and falls under respiratory system diseases. The gold standard for the diagnosis of malignant tumors is biopsy. Thus, lung cancer is no exception; it requires a biopsy and immunohistochemistry to determine the type of cancer and its pathological type. So how is the biopsy obtained? We can use a bronchoscope to directly observe the tumor and collect small tissue samples for pathological examination. Additionally, there is the thoracic wall lung puncture biopsy, where tissue from the tumor can be sampled using a fine needle. These samples are observed under a microscope to differentiate the pathological types and to further confirm the diagnosis.

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How to detect early symptoms of lung cancer?

So, the early symptoms of lung cancer often include a cough, hemoptysis, difficulty breathing, and chest pain. However, these symptoms, particularly the irritating cough, typically appear after the tumor has grown in the larger bronchi; this is often mistaken for a cough following a cold, leading to misdiagnosis or delayed treatment. Therefore, if this type of irritating cough occurs, it is essential to seek medical attention promptly and to undergo chest X-ray or CT scan. Second, as the tumor continues to grow and affects the drainage of the bronchus, secondary lung infections may occur, often characterized by coughing up pus-like sputum, and an increase in the amount of sputum, which should also be noted. Third, a very common symptom is the presence of blood in the sputum, or streaks of blood, or intermittent minor hemoptysis, which must be taken seriously.

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Will people with lung cancer experience weight loss?

This question should be answered specifically. Some people may initially experience symptoms such as weight loss and fatigue when they start to develop lung cancer. Some people with better physical constitution may not lose weight so easily. However, if a malignant tumor persists in the body for a long time, it will consume the body's nutrients and lead to a state of cachexia, characterized by systemic toxicity symptoms including weight loss, fatigue, fever, and other similar symptoms.