What is the best medicine to take for rheumatoid arthritis?

Written by Li Jing
Rheumatology
Updated on September 06, 2024
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Rheumatoid arthritis is a clinical manifestation of rheumatic fever, which is a delayed sequelae that occurs after infection with streptococci. The most common symptoms include fever, arthritis, rheumatic heart disease, subcutaneous nodules, or marginal erythema. It mainly occurs in adolescents and is most commonly triggered by cold weather and damp environments. In cases showing joint symptoms, the first choice of medication is nonsteroidal anti-inflammatory drugs (NSAIDs). Additionally, it is crucial to actively treat the primary disease, which means eliminating the causative factor by eradicating the streptococcal infection. Eradication of the streptococcal infection involves the use of long-acting penicillin, and it is necessary to complete the treatment course of two weeks. Moreover, appropriate rest during the acute phase and avoiding exertion is needed. (Please use medication under the guidance of a professional physician and do not self-medicate.)

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Written by Yang Ya Meng
Rheumatology
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How to cure rheumatoid arthritis?

The treatment methods for rheumatoid arthritis mainly consist of three major categories. The first category is the use of anti-inflammatory and analgesic drugs, commonly including non-steroidal analgesics such as sustained-release diclofenac sodium tablets, and small doses of corticosteroids can also be used. For rheumatoid arthritis, the most important treatment is the choice of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. After using these medications, it is necessary to regularly monitor blood routine tests and liver and kidney functions to check for possible side effects of the drugs. If the effects of the above oral medications are not satisfactory, the application of biologics can also be considered. (Specific medications should be used under the guidance of a doctor, do not self-medicate.)

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Written by Yang Ya Meng
Rheumatology
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How long does it take to cure rheumatoid arthritis?

The symptoms of rheumatic arthritis, such as joint swelling and pain, generally improve on their own within about two weeks, with the longest duration not exceeding one month. However, since rheumatic arthritis is triggered by a Streptococcus infection, if the Streptococcus infection is not actively controlled, it is easy for the arthritis to relapse after the joint pain has improved. Therefore, for patients with rheumatic arthritis, it is essential to treat the Streptococcus infection early. Treatment with second-generation cephalosporin antibiotics for 10-14 days is recommended, followed by regular long-acting benzathine penicillin treatment at outpatient clinics to achieve a complete cure of rheumatic arthritis. (Specific medications should be used under the guidance of a doctor.)

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Written by Yang Ya Meng
Rheumatology
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Can people with rheumatoid arthritis drink alcohol?

Patients with rheumatoid arthritis should avoid drinking alcohol. Due to joint pain, patients with rheumatoid arthritis inevitably consume anti-inflammatory pain relievers or steroids for pain relief. These anti-inflammatory drugs are already harsh on the stomach, and alcohol is similarly harmful. Consuming both anti-inflammatory pain relievers and alcohol can easily lead to gastrointestinal bleeding. Some patients may even develop complications such as gastric ulcers or severe gastrointestinal bleeding. Therefore, it is not recommended for patients with rheumatoid arthritis to drink alcohol. (Medication should be used under the guidance of a doctor.)

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Written by Yang Ya Meng
Rheumatology
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Can rheumatoid arthritis be cured?

Rheumatoid arthritis is difficult to completely cure without medication, as it is a chronic inflammatory disease of the immune system that requires lifelong medication. The main treatment plans include the following three categories: The first category is anti-inflammatory and analgesic, which includes non-steroidal analgesics and low-dose corticosteroids. The second category, which is also the most important treatment, involves the use of immunosuppressants. Commonly used immunosuppressants include methotrexate and leflunomide. If the patient does not respond well to anti-inflammatory analgesics and immunosuppressants, treatment with biological agents may also be considered. (Medications should be used under the guidance of a doctor.)

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Written by Guan Yu Hua
Orthopedic Surgery
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Difference between arthritis and rheumatoid arthritis

Arthritis is typically osteoarthritis, a chronic inflammation characterized primarily by degenerative changes in joint cartilage, followed by bone proliferation, making it a chronic disease. Early pathological changes include alterations in joint cartilage, such as subchondral bone extrusion, followed by changes in the muscles surrounding the periosteum and joint capsule. Early radiographic examinations can provide a definitive diagnosis. Its symptoms primarily manifest as pain. For rheumatoid arthritis, it generally presents as morning stiffness and joint swelling and pain more severe than in the surrounding area, which can essentially confirm a diagnosis. It usually affects large joints such as the knee, shoulder, or wrist joints, typically presenting as migratory pain. A definitive diagnosis can usually be made by testing for rheumatoid factor, with an anti-O level exceeding 500 units. Additionally, there may be a slight increase in white blood cells, accelerated erythrocyte sedimentation rate, and elevated C-reactive protein. Examination of the synovial fluid shows increased white blood cells and neutrophils. In such cases, using anti-rheumatic drugs might suffice, but it’s also crucial to ensure rest and local heat application. These two types of arthritis fundamentally differ.