What are the symptoms of lymphoma?

Written by Liu Liang
Oncology
Updated on September 09, 2024
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The symptoms of lymphoma predominantly start with painless enlargement of superficial lymph nodes, most commonly in areas such as the neck, supraclavicular lymph nodes, armpits, or groin. Additionally, patients with nasal NKT lymphoma might experience nasal congestion, nosebleeds, and rhinorrhea. Lymphomas occurring in the stomach, for example, present symptoms like nausea, vomiting, and even rectal bleeding which are related to the gastrointestinal tract. Therefore, symptoms can vary depending on the location of the lymphoma. Some patients may also experience enlargement of the liver and spleen. In advanced stages of lymphoma, bone marrow involvement is possible, along with common B symptoms including sweating, fever, or weight loss, which are also clinical manifestations seen in lymphoma patients.

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Written by Zhou Zi Hua
Oncology
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Which department do you go to for lymphoma?

If a lump is found on the neck and lymphoma is suspected, the first step is to consult with the head and neck surgery department. The lymphoma lesion will be surgically removed by the department, and then sent for a pathological examination. If lymphoma is confirmed, the next steps involve treatment by the oncology department, hematology department, or radiation therapy department.

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Written by Liu Liang
Oncology
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What are the symptoms of lymphoma?

The symptoms of lymphoma predominantly start with painless enlargement of superficial lymph nodes, most commonly in areas such as the neck, supraclavicular lymph nodes, armpits, or groin. Additionally, patients with nasal NKT lymphoma might experience nasal congestion, nosebleeds, and rhinorrhea. Lymphomas occurring in the stomach, for example, present symptoms like nausea, vomiting, and even rectal bleeding which are related to the gastrointestinal tract. Therefore, symptoms can vary depending on the location of the lymphoma. Some patients may also experience enlargement of the liver and spleen. In advanced stages of lymphoma, bone marrow involvement is possible, along with common B symptoms including sweating, fever, or weight loss, which are also clinical manifestations seen in lymphoma patients.

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Written by Liu Liang
Oncology
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Early symptoms of lymphoma

The early symptoms of lymphoma patients are primarily due to its predilection for lymph nodes, with the majority of cases initially presenting with swollen lymph nodes in the neck or collarbone area. These lymph nodes usually enlarge progressively without pain, which is the most common early clinical symptom. However, some specific types of lymphoma, such as nasal NKT lymphoma, present with localized symptoms like nasal congestion, nosebleeds, or a runny nose. There are also lymphomas originating in the stomach, part of the digestive tract, whose symptoms include upper abdominal pain, nausea, or vomiting. Furthermore, some lymphomas originate in the skin, manifesting as skin nodules. Therefore, depending on the site of occurrence, the symptoms can vary, but the enlargement of superficial lymph nodes remains the primary clinical manifestation in most cases.

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Written by Zhou Chen
Oncology
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What to check for malignant lymphoma?

The examination of lymphoma first requires routine blood tests and blood smears. When aggressive lymphoma invades the bone marrow, anemia, decreased white blood cells, and platelets may occur, and lymphoma cells can appear in peripheral blood; therefore, bone marrow smears and biopsies are necessary. Additionally, blood biochemistry is important, as an increase in lactate dehydrogenase is associated with tumor burden and is an indicator of poor prognosis. Furthermore, Hodgkin's lymphoma may involve the central nervous system, so patients with symptoms of central nervous system involvement need to undergo cerebrospinal fluid examination. The most important aspect of lymphoma is the histopathological examination. Based on the histopathological examination, the pathological staging is determined, and genetic rearrangement can also be performed.

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Written by Liu Liang
Oncology
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Is lymphoma the same as lymphatic cancer?

Lymphoma refers to a type of malignant tumor that originates in lymph nodes or extranodal tissues or organs. The cancer we usually talk about refers to malignant tumors originating from epithelial tissues, which we call cancer, such as lung cancer, liver cancer, etc. Therefore, lymphoma is actually what non-medical professionals commonly refer to as lymphatic cancer. It is simply called lymphoma instead of cancer because it originates in lymph nodes or extranodal tissues or organs, and therefore, it is termed malignant lymphoma, which in layman's terms is lymphatic cancer.