What are the symptoms of lymphoma?

Written by Liu Liang
Oncology
Updated on September 09, 2024
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The symptoms of lymphoma predominantly start with painless enlargement of superficial lymph nodes, most commonly in areas such as the neck, supraclavicular lymph nodes, armpits, or groin. Additionally, patients with nasal NKT lymphoma might experience nasal congestion, nosebleeds, and rhinorrhea. Lymphomas occurring in the stomach, for example, present symptoms like nausea, vomiting, and even rectal bleeding which are related to the gastrointestinal tract. Therefore, symptoms can vary depending on the location of the lymphoma. Some patients may also experience enlargement of the liver and spleen. In advanced stages of lymphoma, bone marrow involvement is possible, along with common B symptoms including sweating, fever, or weight loss, which are also clinical manifestations seen in lymphoma patients.

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Written by Liu Liang
Oncology
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Symptoms of Lymphoma

The symptoms of lymphoma mostly present as painless enlarged superficial lymph nodes, which are common clinical manifestations. Additionally, there may be enlargement of the liver and spleen, with multiple organs throughout the body possibly affected. In advanced stages, patients may experience invasion of the bone marrow. There are also special types of extranodal lymphomas which exhibit specific symptoms. For instance, lymphomas originating in the stomach may present with upper abdominal masses, or symptoms like anemia, weight loss, black stools, and even upper abdominal pain, nausea, and vomiting related to the gastrointestinal tract. If the lymphoma originates in the nasal cavity, known as NK/T-cell lymphoma, symptoms may include tinnitus, nasal congestion, runny nose, and nosebleeds, among others. Some lymphoma patients may also experience fever, generalized weakness, weight loss, collectively referred to as B symptoms.

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Written by Peng Li Bo
Oncology
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Lymphoma rash symptoms

The rash associated with lymphoma is not much different from common rashes; they are both characterized by red papules. However, lymphoma is not an isolated disease. For instance, in patients, one can feel lumps on the neck or upper clavicle area, but they may also exhibit systemic symptoms such as fever, night sweats, weight loss, fatigue, lack of appetite, anemia, chest pain, and other symptoms because it is a systemic disease. Thus, it may cause these systemic symptoms. The rash can also cause itching of the skin.

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Written by Liu Liang
Oncology
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Causes of Malignant Lymphoma

The causes of malignant lymphoma are the result of multiple factors. First, it is associated with infections by bacteria or viruses, such as the well-documented chronic infection with Helicobacter pylori, which is closely related to the occurrence of lymphoma associated with the gastric mucosa. Second, immunodeficiency conditions, like in AIDS patients or those who have been taking immunosuppressive drugs for a long period, have a higher likelihood of developing malignant lymphoma compared to the general population. Third, chemical or physical factors, such as environmental carcinogens and electromagnetic radiation, can also lead to malignant lymphoma. Other factors, such as long-term use of certain drugs like phenytoin or pseudoephedrine, and a genetic predisposition, can also be causes of malignant lymphoma.

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Written by Liu Liang
Oncology
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How is Hodgkin's lymphoma treated?

The treatment of Hodgkin's lymphoma is based on various factors including the stage of the disease as well as the general condition of the patient, among other comprehensive considerations. For patients with early stage Hodgkin's lymphoma, commonly referred to as localized Hodgkin's lymphoma, the treatment principle is a combination of chemotherapy and radiotherapy. A rational comprehensive treatment can achieve a five-year survival rate of 80% to 90%. For advanced-stage patients, such as those with stage IV Hodgkin's lymphoma, the treatment primarily consists of systemic chemotherapy. Therefore, the choice of a specific treatment plan must also consider a variety of factors based on the patient's overall condition.

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Written by Wu Xia
Oncology
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How long can lymphoma last?

In clinical practice, lymphomas are classified into Hodgkin's lymphoma and non-Hodgkin's lymphoma. Non-Hodgkin's lymphoma is a relatively common type of tumor in China and has the highest incidence among lymphomas. However, it is further divided into dozens of subtypes, each with distinct clinical symptoms. Aggressive lymphomas can be cured, while indolent lymphomas can be managed with the tumor remaining. Thus, the question of how long one can live with lymphoma cannot be generalized; it depends on the type and stage of the disease, and many can be cured completely.