The pattern of fever in lymphoma

Written by Liu Liang
Oncology
Updated on September 23, 2024
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Fever symptoms are quite common in patients with lymphoma, which we refer to as B symptoms. The pattern of their fevers is primarily low-grade, occurring more frequently in the afternoon or evening. Unlike ordinary bacterial infections, fevers in these patients do not respond well to anti-inflammatory drugs, but they do respond better to steroid treatment for reducing fever. However, if the lymphoma is not under control, their fever will repeatedly recur. Corresponding cooling treatments can reduce the temperature, but the fever will reoccur repeatedly. Only when the lymphoma and tumor are under control will the fever symptoms start to improve.

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Written by Liu Liang
Oncology
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What is lymphoma?

Lymphoma refers to a type of malignant tumor that originates in the lymph nodes or extranodal tissues or organs. It is clinically categorized into two main types: Hodgkin's lymphoma and non-Hodgkin's lymphoma. Furthermore, it can be subdivided into many different pathological types. Among these, diffuse large B-cell lymphoma is the most common type in China, and there are dozens of different pathological types. The pathological type of the lymphoma determines its malignancy level, prognosis, chemotherapy regimen options, and treatment methods, all of which can vary significantly.

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Written by Liu Liang
Oncology
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The difference between lymphoma and lymphatic cancer

Cancer, commonly referred to as malignant tumors in everyday language, is generally known to the public simply as cancer—for example, lung cancer, liver cancer, colon cancer, etc. It specifically refers to malignant tumors that occur in epithelial tissue, which we call cancer. Lymphoma, on the other hand, refers to malignant tumors that occur in lymph nodes, or in extranodal organs or tissues, which we call lymphoma. There are also malignant tumors that occur in mesenchymal tissue, known as sarcomas. In fact, lymphoma is also a type of malignant tumor, so people commonly refer to it as lymphatic cancer. Therefore, lymphoma and lymphatic cancer are essentially the same disease, with lymphatic cancer specifically referring to lymphoma.

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Written by Peng Li Bo
Oncology
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Lymphoma rash symptoms

The rash associated with lymphoma is not much different from common rashes; they are both characterized by red papules. However, lymphoma is not an isolated disease. For instance, in patients, one can feel lumps on the neck or upper clavicle area, but they may also exhibit systemic symptoms such as fever, night sweats, weight loss, fatigue, lack of appetite, anemia, chest pain, and other symptoms because it is a systemic disease. Thus, it may cause these systemic symptoms. The rash can also cause itching of the skin.

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Written by Liu Liang
Oncology
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What are the symptoms of lymphoma?

The symptoms of lymphoma predominantly start with painless enlargement of superficial lymph nodes, most commonly in areas such as the neck, supraclavicular lymph nodes, armpits, or groin. Additionally, patients with nasal NKT lymphoma might experience nasal congestion, nosebleeds, and rhinorrhea. Lymphomas occurring in the stomach, for example, present symptoms like nausea, vomiting, and even rectal bleeding which are related to the gastrointestinal tract. Therefore, symptoms can vary depending on the location of the lymphoma. Some patients may also experience enlargement of the liver and spleen. In advanced stages of lymphoma, bone marrow involvement is possible, along with common B symptoms including sweating, fever, or weight loss, which are also clinical manifestations seen in lymphoma patients.

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Written by Zhou Chen
Oncology
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What to check for malignant lymphoma?

The examination of lymphoma first requires routine blood tests and blood smears. When aggressive lymphoma invades the bone marrow, anemia, decreased white blood cells, and platelets may occur, and lymphoma cells can appear in peripheral blood; therefore, bone marrow smears and biopsies are necessary. Additionally, blood biochemistry is important, as an increase in lactate dehydrogenase is associated with tumor burden and is an indicator of poor prognosis. Furthermore, Hodgkin's lymphoma may involve the central nervous system, so patients with symptoms of central nervous system involvement need to undergo cerebrospinal fluid examination. The most important aspect of lymphoma is the histopathological examination. Based on the histopathological examination, the pathological staging is determined, and genetic rearrangement can also be performed.