Hand, foot, and mouth disease is spread through:

Written by Yan Xin Liang
Pediatrics
Updated on September 26, 2024
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Hand, foot, and mouth disease is an infectious disease caused by enteroviruses. There are more than 20 types of enteroviruses that can cause the disease, among which Coxsackievirus A16 and Enterovirus 71 are the most common. It frequently occurs in children under the age of 5 and manifests as mouth pain, loss of appetite, low fever, and small blisters or ulcers on the hands, feet, and mouth. Most affected children can recover within about a week. The main routes of transmission for hand, foot, and mouth disease can include the gastrointestinal tract, as well as respiratory transmission, and close contact such as through saliva, cough droplets, etc. Sharing utensils can also spread the disease.

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Written by Feng Hai Tao
Pediatrics
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Symptoms of Hand, Foot, and Mouth Disease in Children

The symptoms of hand, foot, and mouth disease in children primarily result from viral infections of the intestine, a common communicable disease particularly prevalent among children under five, especially those under three years of age. The symptoms can be categorized into typical cases where most children experience a sudden onset of illness, often accompanied by upper respiratory tract infection symptoms such as fever, nasal congestion, runny nose, sneezing, loss of appetite, nausea, and vomiting. Some may also experience headaches. Additionally, rashes or vesicles may appear on the hands, feet, mouth, and buttocks, typically surrounded by inflammatory red skin with little fluid inside the vesicles. These lesions are characterized by being painless, non-itchy, non-crusted, and non-scarring. It is important to note that not all children will have simultaneous rashes on their hands, feet, and mouth areas. In severe cases, while most children experience only mild symptoms and can be isolated at home, some may develop complications involving the nervous system and impairment of respiratory and circulatory functions. This can manifest as muscle spasms, encephalitis, acute flaccid paralysis, cardiopulmonary failure, and neurogenic pulmonary edema. Therefore, once a severe case is identified, hospitalization is recommended to prevent potential fatalities or long-term sequelae.

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Written by Yan Xin Liang
Pediatrics
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Symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is a disease caused by enterovirus that results in sores on the hands, feet, mouth, and buttocks, accompanied by symptoms such as fever. It is generally caused by Enterovirus 71 or Coxsackievirus A16. Most cases of hand, foot, and mouth disease are typical and may involve fever, low fever, or no fever at all. However, common symptoms include sores in the mouth and on the pharynx, as well as on the hands, feet, and buttocks. The general course of the disease lasts five to seven days, but severe cases may last longer. Severe cases may present with symptoms such as listlessness, irritability, vomiting, and trembling limbs. More serious conditions can include microcirculatory disorders, difficulty breathing, shortness of breath, neurogenic edema, and bleeding, among others.

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Written by Yan Xin Liang
Pediatrics
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Late-stage symptoms of hand, foot, and mouth disease

Hand, foot, and mouth disease is an acute infectious disease caused by enterovirus infection. Generally, there are more than twenty types of enteroviruses that cause hand, foot, and mouth disease, but the most common are Coxsackie virus A16 and enterovirus 71. The initial symptoms of hand, foot, and mouth disease are blisters in the hands, feet, and mouth; some cases include fever, while others do not. In later stages, the disease may exhibit recurring fevers, and the blisters on the mouth, hands, feet, and buttocks may burst and crust over. After crusting, the blisters gradually heal, but in some cases, the disease can progress to severe cases. For instance, complications such as encephalitis, brainstem encephalitis, myocarditis can occur, and some cases may develop neurogenic pulmonary edema, pulmonary hemorrhage, and circulatory failure, among others. However, such severe cases are generally rare.

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Written by Yan Xin Liang
Pediatrics
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How to prevent hand, foot, and mouth disease?

Hand, foot, and mouth disease is an infectious disease caused by enteroviruses, with over 20 types, commonly Coxsackievirus A16 and Enterovirus 71. These viruses are mainly transmitted through respiratory and digestive tracts, such as through droplets, hand-mouth contact, and lack of hygiene, leading to infection. To prevent this disease, first, avoid contact with individuals infected with hand, foot, and mouth disease. Second, ensure good ventilation in rooms and avoid crowded places. Additionally, it's best to clean and disinfect utensils and daily necessities. During the epidemic period, try to minimize visits to public places.

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Written by Li Jiao Yan
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How to disinfect hand, foot, and mouth disease?

Hand, foot, and mouth disease is an acute infectious disease caused by a viral infection. It mainly spreads through the respiratory tract, digestive tract, and close contact. Being in contact with a carrier or a child with the disease can result in transmission. It is important to properly handle the infected child's feces and other excretions. Clothes can be soaked in a 3% bleach solution and exposed to sunlight. Keep the room well-ventilated. Other contaminated daily items, such as toys or closely contacted objects like dishware and children's eating utensils, should be disinfected promptly.