Patients with severe anemia may exhibit low-grade fever due to the severity of the anemia, where the fever generally does not exceed 38 degrees Celsius, mostly hovering around 37.5 degrees Celsius. Besides, if a patient with anemia develops high fever above 38 degrees Celsius, even reaching around 39 degrees Celsius, it is crucial to be vigilant about a possible secondary infection due to poor resistance from anemia. It is important to actively search for the source of infection, complete tests such as inflammatory markers, CT scans, and ultrasound imaging, and, once an infectious fever is suspected, to initiate aggressive anti-infection treatment.