How long does it take for someone with ALS to go from onset to paralysis?

Written by Liu Hong Mei
Neurology
Updated on September 17, 2024
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Patients with amyotrophic lateral sclerosis generally progress from onset to paralysis within three to four years. The condition typically involves the progressive degeneration, degeneration, and necrosis of brain nerve cells. Severe and irreversible damage can occur in the brain, spinal cord, and peripheral nerves, also known as motor neuron disease. Motor neuron disease restricts our movement, speech, swallowing, breathing, and muscle activity, causing muscles to gradually atrophy and degenerate, leading to progressive weakness and paralysis. Even speaking, swallowing, and breathing functions degrade, potentially leading to respiratory failure and life-threatening situations, requiring proactive treatment.

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Written by Liu Hong Mei
Neurology
1min 10sec home-news-image

Is it normal for someone with ALS to have severe swelling in their feet?

ALS patients with severe foot swelling is not normal. If an ALS patient experiences severe swelling of the feet, it is important to be cautious of the formation of blood clots in the lower limb vessels. The formation of venous blood clots can lead to poor blood circulation, easily causing blood stasis and thrombotic obstruction, leading to severe swelling of the feet. It is necessary to conduct a Doppler ultrasound of the lower limb vessels to assess their condition. Treatments may include anti-platelet aggregation, anticoagulation, promoting blood circulation to remove blood stasis, and providing nutritional support to nerves. Heat application, keeping warm, promoting lower limb blood circulation, acupuncture, physical therapy, massage, and heat application can be used as symptomatic treatments. For ALS patients with severe foot swelling, it is advisable to elevate the lower limbs during sleep, perhaps covering them with a blanket or elevating them about 45 degrees.

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Written by Liu Shi Xiang
Neurology
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Does amyotrophic lateral sclerosis skip generations in inheritance?

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, may possibly be inherited through generations. The exact cause of ALS is still not very clear, but there is a certain genetic predisposition. Patients with ALS gradually experience symptoms such as limb weakness and muscle atrophy. As the disease progresses, it will eventually lead to difficulties in speech, swallowing disorders, and breathing difficulties, resulting in the patient losing the ability to take care of themselves independently and requiring full-time care from others. Currently, ALS is an incurable disease. The treatment available to patients includes medications to nourish the nerves and systematic rehabilitation training. However, this treatment can only improve the symptoms to a certain extent and enhance the quality of life but cannot stop the progression of the disease. Eventually, the patient will be confined to bed.

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Written by Zhang Hui
Neurology
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Can amyotrophic lateral sclerosis be relieved?

Amyotrophic lateral sclerosis (ALS) refers to a motor neuron disease, and generally speaking, there are no effective alleviation measures for this disease. Currently, the specific causes and pathogenesis of this disease are not very clear. Various factors lead to the simultaneous damage of both upper and lower motor neurons in patients. Clinical manifestations include muscle weakness, muscle atrophy, and fasciculations. Additionally, patients may experience difficulties with swallowing, choking while drinking water, and speech disorders. In its most severe form, it can affect breathing, leading to respiratory failure. This disease progressively worsens, and the prognosis is generally poor with no effective relief methods available.

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Written by Liu Hong Mei
Neurology
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How to exercise for swallowing difficulties in people with amyotrophic lateral sclerosis

Swallowing difficulties in amyotrophic lateral sclerosis primarily involve exercises for oral muscles. Improvement in the movement of oral muscles can alleviate symptoms of swallowing difficulties. Rehabilitation training for oral muscle disorders mainly includes enhancing the movements of the lips, tongue, and lower jaw. Individuals with amyotrophic lateral sclerosis who have brainstem damage and medullary damage may experience swallowing difficulties, water drinking issues, and cough choking, primarily due to sensory disturbances in the throat. By utilizing temperature and sensory stimulation, the sensation in the patient's throat can be restored, allowing them to perceive the temperature and taste of food, thus reducing aspiration. After brainstem damage, the cricopharyngeal muscle does not open, which can be improved through balloon dilation and medication to enhance swallowing function.

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Written by Shi De Quan
Neurology
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Can early-stage ALS be cured?

Amyotrophic lateral sclerosis, also known as motor neuron disease, is a condition that exclusively affects motor neurons without involving sensory neurons. Even if identified early, there are currently no specific medications to cure this disease; treatment can only be symptomatic and rehabilitative. Such approaches can alleviate symptoms. When symptoms are initially mild, medication can only slow down its progression but cannot cure it. The condition inevitably worsens gradually. Rehabilitative treatment can help reduce symptoms or delay the progression of the disease.