Is surgery necessary for teratoma?

Written by Sun Shan Shan
Obstetrics and Gynecology
Updated on February 26, 2025
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Ovarian teratoma belongs to a type of germ cell tumor. Ovarian teratomas can be classified into mature teratomas and immature teratomas. Mature teratoma, also known as dermoid cyst, is mostly a benign tumor. Within the cyst, components such as sebum, hair, teeth, and bone can be found. Additionally, mature teratomas have a malignant transformation risk of 2%-4% and are commonly seen in postmenopausal women. On the other hand, immature teratomas are malignant tumors, accounting for 1%-3% of ovarian teratomas and more commonly found in younger patients, with the average age ranging from 11 to 19 years old. Therefore, timely surgical treatment is necessary once an ovarian teratoma is detected.

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Written by Hou Jie
Obstetrics and Gynecology
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Teratoma Benign and Malignant Differences

Teratoma refers to a common type of germ cell tumor, which can be classified into mature teratomas and immature teratomas. Mature teratomas are benign tumors, accounting for 10%-20% of ovarian tumors. They can occur at any age but are more common between the ages of 20 and 40. Most are unilateral, of moderate size, and usually have a single compartment filled with sebum and hair; sometimes teeth and bone can also be found. Immature teratomas, on the other hand, are malignant tumors, making up 1%-3% of ovarian teratomas. These are more frequent in younger patients, with an average age of 11 to 19 years. The ovaries are predominantly solid but may include cystic areas, primarily consisting of primitive neural tissue. The malignancy level of the ovary depends on the proportion of immature tissue, the degree of differentiation, and the content of neuroepithelial tissue.

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Written by Shen Li Wen
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Can ovarian teratomas affect menstruation?

Women with ovarian teratomas, when they are relatively small, usually do not affect the menstrual cycle. However, as they grow larger, they may compress the normal ovarian cortex, leading to abnormal ovulation, abnormal hormone secretion levels, disruption of the menstrual cycle, and can also cause difficulties in getting pregnant. Additionally, ovarian teratomas belong to germ cell tumors, which are multi-layered but can also develop into a single layer. Some teratomas are highly single-layered and can secrete certain hormones that affect women's endocrine system, thereby affecting the menstrual cycle.

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Written by Xu Xiao Ming
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Does teratoma require blood tests?

If a patient with a teratoma needs to undergo a blood test, the blood test may include routine blood work and blood biochemistry, as well as tumor marker tests such as CA125 and alpha-fetoprotein (AFP) to check for any abnormal increases. If surgery is required for the patient, there might be additional blood tests conducted, including lipid profile, thyroid function tests, and infection and immunity tests. All these require blood draws for the examination.

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Written by Shen Li Wen
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Do teratomas hurt?

Teratomas themselves do not cause pain, especially when they are relatively small, women often have no clinical symptoms. As the size gradually increases, the tumor pulls on the surrounding ligaments, causing abdominal discomfort, such as a feeling of abdominal heaviness, or even abdominal pain. Some women may also experience infection or adhesions with surrounding tissues, leading to abdominal pain. Additionally, some women may have malignant transformation of their teratoma, which invades surrounding tissues and nerves, possibly causing headaches. A small number of women may experience a change in the position of the teratoma after pregnancy or urination, leading to torsion, which can obstruct the blood flow to the tumor, resulting in necrosis and bleeding, causing acute abdominal pain.

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Written by Xu Xiao Ming
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Is ovarian teratoma cancer?

Ovarian teratomas are divided into benign and malignant types. If the teratoma is malignant, then it is a type of cancer. If it is benign, it is not cancer; it is just a tumor. The malignancy of a tumor is not as high as that of cancer. Therefore, it is necessary to determine its pathological type. After removing the teratoma, it should be sent to the pathology department for examination to clearly determine whether it is benign or malignant. For benign teratomas, postoperative follow-up observation is sufficient. However, if the teratoma is malignant, the scope of the surgery should be conducted according to the protocols for ovarian cancer, and chemotherapy is required after surgery.