Does a teratoma that is too large affect fertility?

Written by Yan Qiao
Obstetrics and Gynecology
Updated on April 01, 2025
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Ovarian teratoma is a type of commonly seen benign ovarian tumor. Even though it is benign, like in the case of teratomas, it can still potentially affect a woman's fertility. The critical factors are the location and the size of the ovarian tumor. If the tumor originates from the center of the ovary, it is likely to cause significant damage to the ovarian tissue. Additionally, if the tumor is large, it can also cause substantial damage to the normal tissue. These factors can impact a woman’s fertility, leading to a decline or even complete loss of reproductive function. Whether fertility is retained depends on the function of the ovary on the other side.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Does teratoma require blood tests?

If a patient with a teratoma needs to undergo a blood test, the blood test may include routine blood work and blood biochemistry, as well as tumor marker tests such as CA125 and alpha-fetoprotein (AFP) to check for any abnormal increases. If surgery is required for the patient, there might be additional blood tests conducted, including lipid profile, thyroid function tests, and infection and immunity tests. All these require blood draws for the examination.

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Written by Liu Wei Jie
Obstetrics
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Ovarian teratoma grows during pregnancy

Will ovarian dermoid cysts grow larger after pregnancy? According to clinical experience, there is no correlation between ovarian dermoid cysts and pregnancy status. If there was a dermoid cyst before pregnancy, it is sufficient to monitor its changes during pregnancy check-ups. Generally, ovarian dermoid cysts do not grow larger after pregnancy. However, it is important to note that ovarian dermoid cysts are prone to torsion and rupture. Therefore, patients with ovarian dermoid cysts should be attentive to any abdominal pain during pregnancy. If there is no abdominal pain, generally there should not be a major issue.

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Written by Du Rui Xia
Obstetrics
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The difference between ovarian teratoma and cysts

Ovarian teratomas and ovarian cysts are two completely different diseases. Ovarian teratomas are caused by congenital factors and are tumors of the germ cells that can be benign or malignant, usually requiring surgical removal for treatment. Ovarian cysts, on the other hand, are caused by various factors in women, such as poor lifestyle habits or an imperfect diet structure, leading to a hormonal disease. Ovarian cysts can be physiological or pathological. Usually, physiological ovarian cysts gradually disappear with the menstrual cycle, while pathological ovarian cysts can also be benign or malignant. The need for surgical treatment depends on the nature, size, and clinical symptoms of the ovarian cyst.

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Written by Sun Shan Shan
Obstetrics and Gynecology
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Are teratomas mostly benign?

Ovarian teratomas belong to the category of germ cell tumors, which are divided into mature teratomas and immature teratomas. Immature teratomas are malignant and account for 1%-3% of ovarian teratomas, thus they occur relatively less frequently. These are more commonly found in young patients, with an average age of 11-19 years. Mature teratomas, also known as dermoid cysts, are benign and can account for 10%-20% of ovarian tumors and 85%-97% of germ cell tumors, comprising over 95% of ovarian teratomas. These can occur at any age, but are most common between 20-40 years, often unilateral, and may contain components such as fats, hair, and sometimes teeth and bone tissues. Thus, the majority of mature teratomas are benign tumors.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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Symptoms of ovarian teratoma

In clinical practice, some women with ovarian teratoma may not exhibit any symptoms and the presence of an ovarian teratoma might only be discovered during a physical examination. In some cases, women with ovarian teratoma may experience torsion of the tumor after vigorous activity. When torsion occurs, the patient may suddenly feel pain in one side of the lower abdomen, accompanied by nausea and vomiting. If these symptoms occur, it is necessary to seek immediate medical attention and, if necessary, undergo timely surgical treatment.