Is kidney cancer the same as uremia?

Written by Zhou Qi
Nephrology
Updated on February 17, 2025
00:00
00:00

Kidney cancer and uremia are two completely different concepts. Kidney cancer refers to the presence of a malignant tumor, which is a malignant lesion in kidney-type tissues. Certain cells in the kidney are in a state of limitless proliferation, continuously replicating to form kidney-like masses, and may cause hematuria, or even squeeze kidney tissues affecting their function. Uremia, on the other hand, refers to long-term chronic damage to the kidneys from various diseases, leading to the destruction of over 90% of kidney tissue, rendering the kidneys unable to excrete metabolic waste. This results in azotemia, electrolyte disorders, and other complications, a state known as uremia. Patients with kidney cancer, if the damage to kidney tissues is not severe, may still have normal kidney function. However, if severe problems occur in both kidneys, kidney cancer could also lead to uremia, although this situation is relatively rare.

Other Voices

doctor image
home-news-image
Written by Zou De Bo
Urology
43sec home-news-image

Kidney cancer thrombus

Tumor thrombus is one of the common complications of tumors, and refers to cancer cells in blood vessels or lymphatic vessels similar to blood clots, i.e., cancer cells clustering together, invading the vessels, and causing abnormalities in blood coagulation function, leading to disorders in blood circulation and abnormal coagulation with clustered cancer cells. Generally, the risk of tumor thrombus formation is very high, and patients with tumor thrombus have much worse treatment outcomes than those without. Renal cancer is also a tumor commonly associated with tumor thrombus. Once a tumor thrombus occurs, it indicates that the surgery might be staged quite late, and thus, its treatment results are also relatively poor.

doctor image
home-news-image
Written by Xu Chun Hua
Urology
36sec home-news-image

Survival rate after early removal of kidney cancer

The prognosis of renal cancer is closely related to its clinical staging. If it is in the early stages, surgery is the preferred treatment and the prognosis is very good. Timely surgery followed by subsequent treatments such as immunotherapy, targeted therapy, etc., is recommended. For early-stage renal cancer, the five-year survival rate after surgical removal can exceed 90%, and some patients may live without issues for over 20 years. How long someone lives specifically also depends on the individual's constitution and physical condition.

doctor image
home-news-image
Written by Wang Jian
Urology
58sec home-news-image

Treatment Plans for Renal Cancer

The treatment principles for kidney cancer vary depending on the stage of the cancer. For localized or locally advanced kidney cancer, surgical treatment is primarily used. For advanced kidney cancer, a comprehensive medical treatment approach is mainly used. Surgical treatment is typically the first choice for treating kidney cancer and is currently recognized as a curative method. In early stages, kidney-sparing surgery or radical nephrectomy can be performed using either laparoscopic or open surgery. For mid to late-stage kidney cancer patients, radical nephrectomy is commonly performed as an open surgery. For advanced kidney cancer, treatment primarily involves medical management, which may include surgical removal of the affected kidney. Additionally, treatments can be supplemented with immunotherapy or targeted therapy to improve treatment efficacy. Therefore, different stages of kidney cancer require different treatment plans.

doctor image
home-news-image
Written by Xu Chun Hua
Urology
48sec home-news-image

How is kidney cancer diagnosed?

Hematuria, pain, and lumps are the main symptoms of kidney cancer. If one or two of these symptoms appear, the possibility of kidney cancer should be considered. About half of the patients are found to have incidental kidney cancers, also known as asymptomatic kidney cancers, during physical examinations through incidental findings on ultrasound or CT scans. Some may show early symptoms of metastasis making the diagnosis quite challenging. The preoperative diagnosis of kidney cancer relies on the results of medical imaging examinations such as ultrasound, X-rays, and CT scans. CT scans have a very high confirmation rate for kidney cancer and are currently the most reliable imaging method for diagnosing kidney cancer.

doctor image
home-news-image
Written by Yan Chun
Oncology
1min home-news-image

Kidney cancer most commonly metastasizes to which locations?

Kidney cancer clinically tends to metastasize through direct spread, the lymphatic pathway, and the hematogenous pathway. The lymphatic route often involves enlargement of the perirenal lymph nodes or the lymph nodes in the groin or retroperitoneum. Kidney cancer is also prone to metastasize to the lungs, liver, bones, and other parts via the bloodstream. Similarly, kidney cancer can spread to the perirenal area, ureters, bladder, and other parts through direct extension. Once kidney cancer metastasizes to other organs, it is considered to be in the advanced stages clinically, and treatment primarily involves targeted therapy, chemotherapy, and other comprehensive treatment measures, with surgical treatment not being used as the primary anti-tumor treatment. Once kidney cancer has metastasized, the clinical staging is late, and the prognosis for the patients is poor.