What causes colon cancer?

Written by Yan Chun
Oncology
Updated on January 17, 2025
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Colorectal cancer is a malignant tumor of the digestive system, and its occurrence is related to the following factors:

First, dietary factors. A high-fat content and a low fiber content in the diet both lead to an increased incidence of colorectal cancer. Furthermore, long-term consumption of pickled foods can also increase the incidence of colorectal cancer, presumably because these foods contain higher levels of nitrosamine carcinogens.

Second, some benign chronic diseases of the colon, such as adenomatous polyps and certain chronic colitis, can also lead to an increased incidence of colorectal cancer.

Third, environmental factors. Epidemiological studies have found that the occurrence of colorectal cancer is related to geographical distribution. In some environments with a high incidence of colorectal cancer, the content of some trace elements in the soil is too low, leading to a high incidence of colorectal cancer.

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How to deal with Stage II colon cancer?

For patients diagnosed pathologically with stage II colon cancer, postoperative adjuvant therapy should be considered as appropriate. Colon cancer is a common malignant tumor of the digestive tract in China, originating from the mucosa of the colon, with adenocarcinoma being the most common pathological type. Patients presenting symptoms such as bloody stools or changes in stool shape should be considered for a diagnosis of colon cancer. Those suspected of colon cancer should undergo a colonoscopy as soon as possible. During the colonoscopy, colon mass can be detected, and tissue can be taken from the mass for pathological biopsy. For patients definitively diagnosed with colon cancer, surgery is the preferred treatment. After surgery, patients whose postoperative pathology confirms stage II often require postoperative adjuvant chemotherapy, typically lasting up to six months.

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Colon cancer surgical methods

The surgical approach for colon cancer should be tailored based on the specific circumstances of the patient, involving a rational, comprehensive treatment strategy. The surgical principle is that early-stage cancers should undergo curative resection, while more advanced cancers should be treated with radical surgery or extended radical surgery. Once the treatment plan is determined, the choice of surgical methods should be made comprehensively based on the patient's specific conditions. For example, in the surgery of rectal cancer in the middle and lower segments, it should be considered whether to preserve the anus or perform abdominoperineal resection based on the tumor's biological characteristics, patient's age, overall health, and any concurrent diseases. It is not that there is one fixed type of surgery; the approach should be specifically tailored based on the detailed analysis of the issues at hand.

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Is minimally invasive surgery suitable for transverse colon cancer?

Transverse colon cancer can also be considered for minimally invasive surgical treatment. The main procedure involves a complete resection of the transverse colon, and sometimes, it may require the resection of part of other organs. For instance, if the cancer has invaded the splenic region of the colon, a splenectomy may be necessary. If there is invasion into the liver area, partial liver resection may be needed. In cases where minimally invasive surgery is not suitable or inconvenient, it is also possible to switch to open surgery. The goal is to completely remove the tumor. Whether minimally invasive or traditional surgery is used, it is just a method of operation. Additionally, postoperative adjunct chemotherapy and other comprehensive treatments are necessary.

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Is stage II-III colon cancer considered late stage?

Patients with stage II and III colon cancer are not yet considered to be in the classic advanced stages. Current oncology believes that colon cancer is categorized as stage IV and considered advanced when distant metastases occur. Common sites of metastasis for colon cancer include the liver, lungs, and bones. Stage II colon cancer patients do not have metastases to the pericolic lymph nodes, which is relatively early; stage III colon cancer patients have metastases to the pericolic lymph nodes, which is later than stage II, but as long as there are no distant metastases, it does not reach the advanced stage IV.

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Is lower right abdominal pain colon cancer?

Pain in the lower right abdomen does not necessarily indicate colon cancer, as there are many possible causes of this pain. Common conditions include acute or chronic appendicitis, gynecological diseases such as pelvic inflammatory disease, torsion of a right ovarian cyst, ectopic pregnancy, and others. Additionally, urological issues like a stone in the lower part of the right ureter can cause severe pain in the lower right abdomen, which are again not indicative of colon cancer. Gastrointestinal diseases like Crohn's disease often lead to pain in the lower right abdomen. Of course, tumors in the ileocecal area or ascending colon can also cause such pain. Hence, while lower right abdominal pain is not necessarily due to colon cancer, in rare cases, it could be.