recurrence rate of throat cancer after surgery

Written by Xu Qing Tian
Otolaryngology
Updated on January 18, 2025
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Throat cancer is a common malignant tumor in the head and neck diagnosed by otolaryngologists. Its occurrence is often related to prolonged smoking, drinking, air pollution, and other adverse environmental factors. Currently, the primary treatment for throat cancer is surgical intervention. The likelihood of recurrence after surgery varies from person to person. For early-stage throat cancer patients, the chance of recurrence is relatively low if a thorough excision is performed. Complete recovery rates are usually above 70%-80%. However, for patients with lymph node metastasis in the middle to late stages, recurrence rates are typically above 50%-60%.

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Written by Zhang Jun
Otolaryngology
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Do the early symptoms of laryngeal cancer include coughing?

Throat cancer refers to malignant tumors that occur in the pharyngeal region. Clinically, it commonly manifests as vocal cord cancer, pyriform sinus cancer, and hypopharyngeal cancer. The causes are linked to long-term smoking, alcohol consumption, gastrointestinal dysfunction, acid reflux, irritations, and improper or excessive use of the voice leading to cellular mutations. In its early stages, patients generally experience persistent worsening hoarseness. Sometimes, patients may also suffer from irritative coughing, a foreign body sensation in the throat, obstruction feeling, and breathing difficulties. Patients need to undergo a detailed examination with an electronic laryngoscope at a hospital, which can reveal cauliflower-like neoplasms in any part of the pharynx. At this point, a local biopsy is necessary. If the biopsy confirms a malignant tumor in the pharyngeal region, local surgical removal is required, followed by relevant radiotherapy or chemotherapy.

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Written by Yan Chun
Oncology
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Does CEA increase in throat cancer?

In the blood tests of some laryngeal cancer patients, an increase in the CEA index may be observed, but most laryngeal cancer patients do not exhibit abnormal CEA levels. This is because laryngeal cancer is a common malignant tumor in the head and neck region, and currently, there are no specific tumor markers clinically for laryngeal cancer. CEA, also known as carcinoembryonic antigen, is a tumor marker that is most often elevated in the bodies of patients with malignant tumors. Clinically, an increase in the CEA level is commonly seen in malignant tumors of the gastrointestinal tract, thoracic malignancies, malignancies in the female urogenital system, and some tumors in the male urogenital system. However, in patients with head and neck malignancies, this marker is not commonly elevated.

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Written by Li Mao Cai
Otolaryngology
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Early symptoms of throat cancer

The early symptoms of laryngeal cancer vary depending on the type, as laryngeal cancer is categorized into three types. The most common type, accounting for over 80%, is glottic cancer. The early symptom for this type is primarily hoarseness, making it the type of laryngeal cancer where symptoms appear earliest. The other two types are supraglottic and subglottic cancer. These types are less likely to show early symptoms, or the symptoms may not be typical and easily noticeable or taken seriously. The main symptom is a foreign body sensation in the throat, which is often mistaken for pharyngitis or laryngitis and not given due attention. Therefore, when experiencing persistent hoarseness or a noticeable foreign body sensation in the throat, and if throat discomfort persists, it is advised to visit the Ear, Nose, and Throat (ENT) department of a hospital promptly for an examination with an electronic laryngoscope. This can help in the early detection, exclusion, and diagnosis of the condition.

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Written by Xu Qing Tian
Otolaryngology
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Throat cancer coughing up blood, what is going on?

Patients with laryngeal cancer may experience bleeding due to the rupture of local tumors. The surface tissue of tumors that develop in laryngeal cancer is relatively fragile, and may rupture and cause bleeding during stimuli such as eating or coughing. When these symptoms occur, it is crucial to visit a hospital for medical consultation immediately. Examinations like indirect laryngoscopy and electronic nasopharyngoscopy can help confirm the patient's symptoms and make an accurate diagnosis. Under the guidance of a physician, hemostatic drugs, antibiotics, and hormones can be used for temporary symptomatic treatment. Patients with laryngeal cancer should be detected and treated early, undergo surgery as soon as possible, and receive radiation and chemotherapy to ensure their survival.

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Written by Li Rui
Otolaryngology
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Is throat cancer prone to recurrence?

Throat cancer indeed may recur, but the specific chances and extent of recurrence vary greatly among individuals. Generally speaking, the probability of recurrence is much lower in early-stage throat cancer compared to mid and late stages. For early-stage throat cancer, surgery or radiotherapy is primarily recommended. The first two years are very critical; if there is no recurrence within two years, the likelihood of recurrence is relatively smaller. Then, the next milestone is five years; the five-year survival rate is very significant. If there is no recurrence within five years, it can generally meet the criteria for clinical cure. However, even after five years, a small portion of patients might still experience recurrence, hence the necessity to persist with long-term follow-up examinations.