Where is throat cancer likely to metastasize?

Written by Zhang Jun
Otolaryngology
Updated on November 17, 2024
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The metastasis of laryngeal cancer primarily involves local spread, mainly to the lymph nodes in zones 2, 3, and 4 of the neck. When the cancer becomes more severe, it can break through the lymphatic vessels and spread to the liver, kidneys, spleen, brain, lungs, and other related areas.

Laryngeal cancer is a malignant tumor of the pharyngeal region, typically caused by long-term smoking, drinking, immunodeficiency, and cellular mutations. It commonly occurs in the vocal cords, esophagus, laryngeal ventricle, piriform sinus, base of the tongue, and epiglottis. It causes patients to feel a foreign body sensation in the throat, persistent hoarseness that progressively worsens, irritative cough, difficulty swallowing, and difficulty breathing. An examination with an electronic laryngoscope can help diagnose the condition.

If an abnormal mass is found, a local biopsy is necessary. If laryngeal cancer is confirmed, related surgical treatment as well as radiotherapy or chemotherapy may be required.

Other Voices

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Written by Xu Qing Tian
Otolaryngology
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The difference between laryngeal cancer and pharyngeal cancer

The main difference between laryngeal cancer and pharyngeal cancer lies in the different parts they affect. Laryngeal cancer occurs below the level of the epiglottis, while pharyngeal cancer generally occurs above this level, including tumors in the pharynx, tonsils, and base of the tongue, whereas laryngeal cancer primarily involves the vocal cords and the lower pharynx. For the diagnosis and treatment of pharyngeal and laryngeal cancers, we can use nasoendoscopy, paranasal sinus CT scan, and CT scan of the larynx among other examinations to make a clear diagnosis, and a pathological biopsy for final confirmation. Once diagnosed, it is usually necessary to surgically remove the tumor promptly to achieve a cure.

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Written by Li Rui
Otolaryngology
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Can acute pharyngitis easily turn into laryngeal cancer?

Acute pharyngitis is unlikely to transform into laryngeal cancer, as it is primarily caused by bacterial or viral infection, with bacterial infections being more common in clinical settings. The main symptoms include sudden throat pain, and some people may also experience a foreign body sensation in the throat or fever. Overall, this disease is characterized as an inflammatory response, and the typical treatment duration is about a week, with recovery generally being rapid, focusing primarily on anti-infection treatment. In terms of inflammation, there is no direct link to laryngeal cancer, so it is not likely to evolve into laryngeal cancer. Moreover, the causes of laryngeal cancer are not yet very clear.

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Written by Li Mao Cai
Otolaryngology
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Is a hoarse voice an indication of throat cancer?

Hoarseness does not necessarily indicate laryngeal cancer because there are many diseases that can cause hoarseness. Common ones include vocal cord nodules, vocal cord polyps, acute laryngitis, chronic laryngitis, vocal cord grooves, and laryngeal cancer. The primary approach should be to visit an ENT (Ear, Nose, and Throat) department in a hospital, undergo an electronic fibrolaryngoscopy, and then determine the specific lesion based on the examination results. It is incorrect to diagnose laryngeal cancer based solely on hoarseness. For instance, some types of laryngeal cancer, such as supraglottic or subglottic, may cause hoarseness symptoms to appear late or even not at all. Therefore, while hoarseness does not necessarily mean laryngeal cancer, laryngeal cancer can potentially cause hoarseness. It is crucial to seek timely medical attention and undergo electronic fibrolaryngoscopy for a basic definitive diagnosis when hoarseness occurs. Apart from diseases of the throat, conditions affecting the thyroid, mediastinum, and esophagus can also cause hoarseness when they progress to a certain stage. Thus, hoarseness is a symptom that can be caused by many diseases, but it is not necessarily indicative of laryngeal cancer. Supraglottic laryngeal cancer, however, can manifest hoarseness as an early symptom. Therefore, it is critical to seek medical attention promptly once this symptom occurs.

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Written by Zhang Jun
Otolaryngology
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Do the early symptoms of laryngeal cancer include coughing?

Throat cancer refers to malignant tumors that occur in the pharyngeal region. Clinically, it commonly manifests as vocal cord cancer, pyriform sinus cancer, and hypopharyngeal cancer. The causes are linked to long-term smoking, alcohol consumption, gastrointestinal dysfunction, acid reflux, irritations, and improper or excessive use of the voice leading to cellular mutations. In its early stages, patients generally experience persistent worsening hoarseness. Sometimes, patients may also suffer from irritative coughing, a foreign body sensation in the throat, obstruction feeling, and breathing difficulties. Patients need to undergo a detailed examination with an electronic laryngoscope at a hospital, which can reveal cauliflower-like neoplasms in any part of the pharynx. At this point, a local biopsy is necessary. If the biopsy confirms a malignant tumor in the pharyngeal region, local surgical removal is required, followed by relevant radiotherapy or chemotherapy.

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Written by Deng Bang Yu
Otolaryngology
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How is advanced malignant throat cancer treated?

Laryngeal cancer is a malignant tumor in the larynx, mainly squamous cell carcinoma. In advanced stages of laryngeal cancer, the main issues are malignant ulcers in the laryngeal area, followed by tumor proliferation, bleeding, and then blockage of the airway by the tumor mass, leading to respiratory difficulties and cachexia throughout the body. Therefore, the primary treatment for advanced malignant tumors is to maintain airway patency, mainly through tracheotomy; secondly, pain management and analgesic treatment are provided to improve the patient’s quality of life; thirdly, nutritional support is provided to the patient, including the insertion of a gastric tube or even parenteral nutrition via intravenous feeding. Overall, the treatment of advanced malignant tumors primarily focuses on improving quality of life and alleviating patient suffering.