How is advanced malignant throat cancer treated?

Written by Deng Bang Yu
Otolaryngology
Updated on January 10, 2025
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Laryngeal cancer is a malignant tumor in the larynx, mainly squamous cell carcinoma. In advanced stages of laryngeal cancer, the main issues are malignant ulcers in the laryngeal area, followed by tumor proliferation, bleeding, and then blockage of the airway by the tumor mass, leading to respiratory difficulties and cachexia throughout the body. Therefore, the primary treatment for advanced malignant tumors is to maintain airway patency, mainly through tracheotomy; secondly, pain management and analgesic treatment are provided to improve the patient’s quality of life; thirdly, nutritional support is provided to the patient, including the insertion of a gastric tube or even parenteral nutrition via intravenous feeding. Overall, the treatment of advanced malignant tumors primarily focuses on improving quality of life and alleviating patient suffering.

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Written by Li Rui
Otolaryngology
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What are the symptoms of throat cancer?

The symptoms of laryngeal cancer are quite varied, and there are some differences among different types of laryngeal cancer. For glottic laryngeal cancer, a common symptom is hoarseness because the cancer primarily develops on the vocal cords. This can lead to incomplete closure of the vocal cords or restricted movement during speech, causing hoarseness. Symptoms generally appear early in the course of the disease for this type. For supraglottic or subglottic laryngeal cancer, symptoms may include throat pain, a feeling of a foreign body, and difficulties in swallowing and breathing. However, hoarseness generally appears later in these cases. The primary treatment is surgery, with some patients requiring consideration for radiotherapy and chemotherapy.

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Written by Deng Bang Yu
Otolaryngology
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Is T2N0M0 throat cancer serious?

Laryngeal cancer T2N0M0 refers to Stage 2 clinical staging of laryngeal cancer. Here, "T" denotes the primary lesion, typically classified as Stage 2. Stage 1 generally refers to the primary tumor, with Stage 2 lesions being larger in scope than Stage 1. "N0" indicates the local lymph nodes, showing that there is no local lymph node metastasis. "M0" indicates there is no distant metastasis. Therefore, laryngeal cancer T2N0M0 represents an early or intermediate stage. Clinically, this stage is usually most suitable for surgery, and the healing and prognosis after surgery are relatively favorable.

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Written by Xu Qing Tian
Otolaryngology
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Recurrence rate after total laryngectomy for throat cancer

Laryngeal cancer is a common disease in otolaryngology and a relatively prevalent malignant tumor. Patients who undergo total laryngectomy often have advanced laryngeal tumors, which block the esophagus or pharynx and have tumor tissues too large for partial removal. The likelihood of recurrence after tumor resection varies from patient to patient, depending on the radiotherapy and chemotherapy administered post-operatively, as well as individual physical constitutions, which can alter recurrence rates. Generally, we recommend that patients undergo a laryngoscopic check-up every three to six months and a CT scan of the larynx post-surgery, to enable timely detection and treatment, aiming for early control and intervention in case of potential recurrence.

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Written by Li Rui
Otolaryngology
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Can throat cancer be detected by a CT scan?

Most laryngeal cancers can be detected through CT scans because, during the scan, it is possible to see whether there are neoplasms in the area of the pharynx and larynx, especially around the laryngeal cavity, ventricle, and vocal cords. Generally, if there are any growths, they will be visible on a CT scan. However, some early-stage laryngeal cancers, where the mucosa has just started to show changes, might be missed by CT scans. In such cases, it is generally recommended to also perform a laryngoscopic examination. If possible, conducting an NBI (Narrow Band Imaging) laryngoscopy could reveal early mucosal changes. If early-stage laryngeal cancer is confirmed by pathology, surgical or radiation treatment can be very effective and generally has a low chance of recurrence.

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Written by Li Rui
Otolaryngology
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Can throat cancer be cured?

Throat cancer is a relatively common malignant tumor in the head and neck area. Some patients can achieve clinical cure, which generally means no local recurrence or distant metastasis for 5 years after the end of treatment. However, the specific treatment outcomes can vary significantly among individuals. Generally, early-stage throat cancer has better treatment outcomes and a higher 5-year survival rate. If it's in the middle to late stages, throat cancer tends to be more difficult to treat and the outcomes are poorer. Therefore, it's important to seek prompt treatment from an otolaryngologist after the onset of the disease, receive targeted treatment, and undergo regular follow-ups to monitor the efficacy of the treatment.