Causes of myasthenia gravis
Updated on February 24, 2025
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Myasthenia gravis is a type of neurological autoimmune disease. The cause and mechanism of this disease are primarily due to disorders in the immune function of the body. Antibodies are produced in the body which attack the acetylcholine receptors at the neuromuscular junction, leading to the failure of nerve impulses being transmitted to the muscles. This results in the clinical symptoms observed. Many patients may have thymic abnormalities, such as thymomas. Treatment of this disease involves the use of cholinesterase inhibitors and suppression of these abnormal immune responses, typically requiring the use of corticosteroids.
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