Myasthenia Gravis Clinical Manifestations

Written by Zhang Hui
Neurology
Updated on January 14, 2025
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Myasthenia gravis is a type of immunological disease of the nervous system that belongs to neurology. The common clinical manifestations include the following aspects. First, some patients may experience ptosis, where they cannot open their eyes. It usually starts on one side and may also involve abnormal eye movements, such as difficulty in moving the eyes to the left or right, leading to double vision and other clinical manifestations. Second, some patients may experience dysphagia, such as difficulty swallowing, choking on water, and speech articulation disorders. Third, some patients may experience weakness in their limbs, especially an inability to perform strenuous physical activities, such as climbing stairs, which can be significantly affected. These clinical manifestations usually show a pattern of being less severe in the morning and more severe in the evening.

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Written by Zhang Hui
Neurology
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Myasthenia Gravis Clinical Manifestations

Myasthenia gravis is a type of immunological disease of the nervous system that belongs to neurology. The common clinical manifestations include the following aspects. First, some patients may experience ptosis, where they cannot open their eyes. It usually starts on one side and may also involve abnormal eye movements, such as difficulty in moving the eyes to the left or right, leading to double vision and other clinical manifestations. Second, some patients may experience dysphagia, such as difficulty swallowing, choking on water, and speech articulation disorders. Third, some patients may experience weakness in their limbs, especially an inability to perform strenuous physical activities, such as climbing stairs, which can be significantly affected. These clinical manifestations usually show a pattern of being less severe in the morning and more severe in the evening.

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Written by Liu Hong Mei
Neurology
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What should people with myasthenia gravis pay attention to in their daily lives?

Patients with myasthenia gravis should be careful to continue taking their medications after being discharged from the hospital and must not change the dosage or administration of their medication on their own. It is important to avoid overexertion and emotional stimuli in daily life. One should ensure to get enough rest, maintain adequate sleep, and consume fresh vegetables and fruits. Avoid spicy, stimulating, and excitatory foods. Do not be overly sad or experience excessive emotional fluctuations. Pay attention to the risk of catching a cold and upper respiratory infections. Take precautions against exposure to cold and prevent infections. Balance work and rest, maintain regular life patterns, keep in good spirits, ensure adequate sleep, and avoid excessive emotional disturbances and stimuli.

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Written by Zhang Hui
Neurology
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What medicine should be taken for myasthenia gravis?

Myasthenia gravis is a type of neurological immunological disease in neurology, mainly caused by a disorder of the body's own immune function. Patients in the body will produce antibodies against acetylcholine receptors, thus affecting the transmission of nerve impulses at the neuromuscular junction. For this disease, the following medications are generally prescribed: The first type of medication is a cholinesterase inhibitor, which can increase the amount of acetylcholine at the neuromuscular junction, thereby effectively improving clinical symptoms. The second type of medication is corticosteroids, because this disease is caused by an abnormal inflammatory response. Therefore, taking corticosteroids can suppress the inflammatory response. Treatment generally starts with a small dose and gradually increases, maintaining for a period before gradually tapering off. It may also be necessary to take other immunosuppressants. (Please take the medication under the guidance of a doctor)

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Written by Zhang Hui
Neurology
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Myasthenia gravis should not use what medicine?

Myasthenia gravis is a neuromuscular junction disease in neurology, primarily due to some synaptic dysfunction, leading to pathological fatigue and general weakness in patients. Patients with myasthenia gravis often experience exacerbation of the disease due to fatigue or infection, and certain medications can severely affect synaptic function, worsening the condition, and are therefore not to be used. The medications to avoid mainly include the following types: The first type is aminoglycoside antibiotics, which can exacerbate the transmission at the neuromuscular junction. Second, quinolone antibiotics should also be avoided as much as possible. Third, some antiarrhythmic drugs can also decrease the excitability of the fascia and are not recommended. Additionally, some drugs like morphine, benzodiazepines, and receptor blockers should also be contraindicated or used with caution.

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Written by Zhang Hui
Neurology
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What department is myasthenia gravis under?

Myasthenia gravis, this disease definitely requires registration with the Department of Neurology as it is a relatively common disease in neurology, and doctors in other departments are not particularly familiar with this disease, let alone diagnosis and treatment. Myasthenia gravis is an immune disease of the nervous system, and patients may experience generalized fatigue, which can be alleviated after rest. It is characterized by clinical symptoms that are lighter in the morning and more severe in the evening. Additionally, symptoms such as ptosis, double vision, and even some difficulties in swallowing and unclear speech, known as bulbar paralysis, may occur. This disease requires a thorough chest CT scan, as many patients have an associated thymoma. Furthermore, an electromyography examination is needed to check for antibodies related to myasthenia gravis, which is also important for guiding further treatment.