Myasthenia Gravis Best Treatment

Written by Tang Bo
Neurology
Updated on April 03, 2025
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The treatment of myasthenia gravis should also be individualized, specifically based on the actual condition of the patient. First and foremost, a clear diagnosis is essential. Once the diagnosis is confirmed, cholinesterase inhibitors can be used, but the dosage and frequency must be decided based on the patient's individual condition. Additionally, if the patient has a thymoma or thymic hyperplasia, a surgeon should determine whether surgical treatment is necessary. It is also necessary to consider whether to use steroids or plasmapheresis. In the event of a myasthenic crisis, symptomatic treatment should be provided according to the situation to maintain the patient's vital signs, and it is crucial to diagnose and treat early.

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Written by Tang Bo
Neurology
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Myasthenia Gravis Best Treatment

The treatment of myasthenia gravis should also be individualized, specifically based on the actual condition of the patient. First and foremost, a clear diagnosis is essential. Once the diagnosis is confirmed, cholinesterase inhibitors can be used, but the dosage and frequency must be decided based on the patient's individual condition. Additionally, if the patient has a thymoma or thymic hyperplasia, a surgeon should determine whether surgical treatment is necessary. It is also necessary to consider whether to use steroids or plasmapheresis. In the event of a myasthenic crisis, symptomatic treatment should be provided according to the situation to maintain the patient's vital signs, and it is crucial to diagnose and treat early.

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Written by Zhang Hui
Neurology
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What should not be eaten in the case of myasthenia gravis?

Myasthenia gravis is an autoimmune disease of the nervous system, primarily due to dysfunction at the neuromuscular junction, leading to skeletal muscle fatigue. Symptoms include drooping eyelids, double vision, overall weakness, and even swallowing difficulties. Foods that should be avoided in myasthenia gravis mainly include certain medications, such as aminoglycoside antibiotics, which should not be taken orally by patients, as well as fluoroquinolone antibiotics. These antibiotics can exacerbate neuromuscular transmission disorders, potentially worsening the disease. Additionally, benzodiazepines, barbiturates, and some anti-arrhythmic drugs can also reduce muscle membrane excitability and should be avoided.

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Written by Tang Bo
Neurology
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Types of myasthenia gravis crisis

Myasthenic crises are categorized into three types, all resulting from worsening conditions or improper treatment, leading to respiratory muscle weakness or paralysis and subsequent difficulty in breathing. The first type occurs due to various triggers or reduction in medication, or after the application of acetylcholinesterase inhibitors which temporarily alleviate the crisis, known as the cholinergic crisis. The second type is a result of excessive use of acetylcholinesterase inhibitors during a cholinergic crisis. Beyond respiratory difficulties, symptoms may also include signs of toxicity such as vomiting, abdominal pain, diarrhea, pupil constriction, excessive sweating, drooling, increased tracheal secretions, and potential muscle tremors, spasms, as well as anxiety, insomnia, confusion, seizures, and coma. The third type is the paradoxical crisis, where neither ceasing nor increasing medication doses alleviates the symptoms, typically occurring after long-term, high-dose medication use.

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Written by Tang Li Li
Neurology
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Myasthenia gravis should be seen in the Neurology department.

Patients with myasthenia gravis should consult the department of neurology, as myasthenia gravis is an immune-related neuromuscular junction disorder. Patients often exhibit pathological fatigue, skeletal muscle involvement, and unaffected smooth muscles. The most common type is ocular myasthenia, followed by mild and moderate generalized forms. Adult patients often have thymomas or thymic hyperplasia. Upon diagnosis of myasthenia gravis, it is essential to perform a comprehensive thymic CT scan. If thymic abnormalities are present, referral to thoracic surgery for treatment is needed. If there is no thymic disease, high-dose steroid pulse therapy may be considered. Additionally, it is crucial to determine whether the patient has other coexisting immune abnormalities, such as hyperthyroidism or connective tissue disease, and tailor the treatment accordingly.

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Written by Zhang Hui
Neurology
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What is a good medicine to take for myasthenia gravis?

Myasthenia gravis is an autoimmune disease of the nervous system. Patients need to take medication for a long time, otherwise, antibodies to acetylcholine receptors might continue to be produced, further worsening the clinical manifestations. The medications taken by patients with myasthenia gravis mainly include the following types, the first being cholinesterase inhibitors. These drugs can inhibit the breakdown of acetylcholine by cholinesterase, thereby improving the transmission function between nerve and muscle junctions, and improving the clinical symptoms of patients. It is best to take these medications before meals for better absorption. The second type of medication mainly includes corticosteroids. They can suppress the body's immune response and reduce the production of antibodies, which is very helpful for the recovery from the disease. Long-term usage and gradual dosage reduction are necessary. Additionally, some immunosuppressants need to be taken. Taking these immunosuppressants also aims to suppress the immune response. However, it is essential to be aware of their adverse effects, such as suppression of bone marrow function, and damage to liver and kidney functions.