Does myasthenia gravis hurt?

Written by Liu Yan Hao
Neurology
Updated on September 13, 2024
00:00
00:00

Myasthenia gravis does not cause pain. Initially, patients with myasthenia gravis may feel discomfort such as soreness or swelling in the eyes or limbs, blurred vision, or fatigue. As the condition progresses, skeletal muscles become noticeably fatigued and weak. A significant characteristic is muscle weakness, which worsens after exertion in the afternoon or evening and improves after rest in the morning, known as "morning better, evening worse." Patients with myasthenia gravis can experience involvement of skeletal muscles throughout the body, manifesting as drooping eyelids, blurred vision, double vision, strabismus, restricted eye movements, bland facial expressions, a "forced smile" appearance, speech impairments resembling a thick tongue often accompanied by a nasal sound. Additionally, they may have chewing difficulties, coughing or choking when drinking, swallowing difficulties, trouble raising the head, weak shoulder shrugging, difficulty lifting arms, combing hair, climbing stairs, squatting, and getting into vehicles, primarily due to muscle weakness, which does not lead to pain.

Other Voices

doctor image
home-news-image
Written by Zhang Hui
Neurology
1min 7sec home-news-image

incidence of myasthenia gravis

Myasthenia gravis is a disease of the neurology department. Its incidence rate is around one in one hundred thousand. The prevalence rate is around fifty per one hundred thousand. In China, the incidence rate in the south is slightly higher than in the north. This is an autoimmune disease of the nervous system. Generally, it is due to the production of some abnormal antibodies. These antibodies cause dysfunction in synaptic transmission at the neuromuscular junction, leading to corresponding clinical manifestations in patients. For example, extreme fatigue after physical activity that can only be alleviated by rest. Patients may also exhibit clinical symptoms such as ptosis, diplopia, and difficulty swallowing, and in severe cases, even respiratory muscle weakness may occur, requiring the use of a ventilator. This disease can occur at any age, affecting children as well as elderly men aged 70 to 80. Therefore, correct understanding of this disease and timely treatment are very important.

doctor image
home-news-image
Written by Zhang Hui
Neurology
55sec home-news-image

Early symptoms of myasthenia gravis

Myasthenia gravis is an autoimmune disease of the nervous system that primarily affects the acetylcholine receptors on the postsynaptic membrane, causing muscle fatigue in patients. This can lead to general weakness throughout the body, double vision, and even progressive paralysis of the respiratory muscles, requiring active breathing assistance in severe cases. The early symptoms of myasthenia gravis mainly include: First, patients tend to fatigue easily, such as after exercise or labor, with a rapid decline in physical strength that only recovers after resting. Second, there may be ptosis, with patients unable to comfortably open their eyes, although this symptom can improve after resting or sleeping. As myasthenia gravis progresses into its later stages, there is a marked increase in overall weakness, necessitating treatment in a neurology department.

doctor image
home-news-image
Written by Shi De Quan
Neurology
29sec home-news-image

Can myasthenia gravis with eyelid drooping be cured?

Myasthenia gravis with ptosis is treatable. The ptosis is a manifestation of myasthenia gravis, which is generally mild. This type of myasthenia gravis is usually treatable with Pyridostigmine. If oral medication is ineffective, using steroids or immunosuppressants can also lead to recovery. This is typically a mild form of myasthenia gravis, so oral medication generally leads to a cure.

doctor image
home-news-image
Written by Zhang Hui
Neurology
57sec home-news-image

What is good to eat for myasthenia gravis?

Myasthenia gravis is an autoimmune disease of the nervous system that primarily affects the neuromuscular junction, leading to muscle weakness and post-exertional fatigue. Some patients may also experience clinical symptoms such as ptosis and diplopia. The main treatments include corticosteroids and immunosuppressants. Patients with myasthenia gravis should pay attention to their diet: First, consume plenty of fresh vegetables and fruits, which are rich in vitamins that can provide sufficient immunity to prevent certain complications. Second, eat foods high in B vitamins, such as animal liver, lean meat, and whole grains, which are beneficial for patients. Third, patients should also consume high-quality proteins, which provide ample nutrition and increase resistance, including items such as milk, beef, and fish.

doctor image
home-news-image
Written by Zhang Hui
Neurology
1min 13sec home-news-image

Types of Myasthenia Gravis Crisis

Myasthenia gravis is a neurological disease. It is an autoimmune disorder primarily affecting the neuromuscular junction, leading to symptoms such as pathological fatigue, ptosis, and limb weakness. Myasthenia gravis is termed as such due to its severe nature, including crises that can impair respiratory muscles, leading to respiratory paralysis, respiratory failure, and potentially death. There are three main types of myasthenic crises. The first type is myasthenic crisis, primarily caused by insufficient medication; muscular injections can be used for treatment, and if effective, it indicates a myasthenic crisis. The second type is called cholinergic crisis, resulting from an overdose of acetylcholinesterase inhibitors, with symptoms including muscular twitching and pupil constriction. The third type is called refractory crisis, occurring when the body is insensitive to medication treatments. All these crises pose a life-threatening risk to patients and require immediate management, including tracheal intubation and, if necessary, mechanical ventilation.