Is it dangerous to have a fever with myasthenia gravis?

Written by Zhang Hui
Neurology
Updated on September 21, 2024
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Myasthenia gravis is a disease of the neuromuscular junction, essentially an autoimmune inflammatory response that causes generalized weakness and fatigue of the skeletal muscles, with symptoms that are less severe in the morning and worsen by the evening, and fluctuate over time. The weakness can be alleviated by rest. When patients with myasthenia gravis develop a fever, it is generally considered to be caused by an infection, perhaps a viral infection such as an upper respiratory tract infection, which can also induce fever. In such cases, the main treatment involves drinking plenty of water and consuming fresh vegetables and fruits. If necessary, some antiviral medications and antipyretics may be administered. If the fever is due to a bacterial infection, symptomatic treatment should be accompanied by the appropriate antibiotics. However, the choice of antibiotics must be made with caution. Patients with myasthenia gravis should not use aminoglycosides or fluoroquinolones, as these could exacerbate their condition. Penicillins or cephalosporins may be used instead. (Please consult a professional physician for specific medication guidance.)

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Written by Zhang Hui
Neurology
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Types of Myasthenia Gravis Crisis

Myasthenia gravis is a neurological disease. It is an autoimmune disorder primarily affecting the neuromuscular junction, leading to symptoms such as pathological fatigue, ptosis, and limb weakness. Myasthenia gravis is termed as such due to its severe nature, including crises that can impair respiratory muscles, leading to respiratory paralysis, respiratory failure, and potentially death. There are three main types of myasthenic crises. The first type is myasthenic crisis, primarily caused by insufficient medication; muscular injections can be used for treatment, and if effective, it indicates a myasthenic crisis. The second type is called cholinergic crisis, resulting from an overdose of acetylcholinesterase inhibitors, with symptoms including muscular twitching and pupil constriction. The third type is called refractory crisis, occurring when the body is insensitive to medication treatments. All these crises pose a life-threatening risk to patients and require immediate management, including tracheal intubation and, if necessary, mechanical ventilation.

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Written by Zhang Hui
Neurology
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What should not be eaten in the case of myasthenia gravis?

Myasthenia gravis is an autoimmune disease of the nervous system, primarily due to dysfunction at the neuromuscular junction, leading to skeletal muscle fatigue. Symptoms include drooping eyelids, double vision, overall weakness, and even swallowing difficulties. Foods that should be avoided in myasthenia gravis mainly include certain medications, such as aminoglycoside antibiotics, which should not be taken orally by patients, as well as fluoroquinolone antibiotics. These antibiotics can exacerbate neuromuscular transmission disorders, potentially worsening the disease. Additionally, benzodiazepines, barbiturates, and some anti-arrhythmic drugs can also reduce muscle membrane excitability and should be avoided.

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Written by Zhang Hui
Neurology
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What is myasthenia gravis?

Myasthenia gravis is a group of neuromuscular junction disorders and is also an autoimmune disease of the nervous system. It primarily involves the production of certain antibodies in the body that attack the acetylcholine receptors on the postsynaptic membrane of the neuromuscular junction. This results in the inability of nerve impulses to be effectively transmitted to the muscles, causing the muscles to lose neural control, leading to weakness of the limbs. This weakness is typically more pronounced in the evening than in the morning, with symptoms being lighter upon waking and worsening in the afternoon. As the disease is caused by an autoimmune response, a major focus of treatment is to suppress this abnormal immune reaction, primarily through the administration of corticosteroids. Additionally, many patients with myasthenia gravis also exhibit thymus abnormalities, necessitating thorough CT examinations of the thymus.

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Written by Zhang Hui
Neurology
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Early symptoms of myasthenia gravis

Myasthenia gravis is an autoimmune disease of the nervous system that primarily affects the acetylcholine receptors on the postsynaptic membrane, causing muscle fatigue in patients. This can lead to general weakness throughout the body, double vision, and even progressive paralysis of the respiratory muscles, requiring active breathing assistance in severe cases. The early symptoms of myasthenia gravis mainly include: First, patients tend to fatigue easily, such as after exercise or labor, with a rapid decline in physical strength that only recovers after resting. Second, there may be ptosis, with patients unable to comfortably open their eyes, although this symptom can improve after resting or sleeping. As myasthenia gravis progresses into its later stages, there is a marked increase in overall weakness, necessitating treatment in a neurology department.

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Written by Zhang Hui
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incidence of myasthenia gravis

Myasthenia gravis is a disease of the neurology department. Its incidence rate is around one in one hundred thousand. The prevalence rate is around fifty per one hundred thousand. In China, the incidence rate in the south is slightly higher than in the north. This is an autoimmune disease of the nervous system. Generally, it is due to the production of some abnormal antibodies. These antibodies cause dysfunction in synaptic transmission at the neuromuscular junction, leading to corresponding clinical manifestations in patients. For example, extreme fatigue after physical activity that can only be alleviated by rest. Patients may also exhibit clinical symptoms such as ptosis, diplopia, and difficulty swallowing, and in severe cases, even respiratory muscle weakness may occur, requiring the use of a ventilator. This disease can occur at any age, affecting children as well as elderly men aged 70 to 80. Therefore, correct understanding of this disease and timely treatment are very important.