Gonorrhea and AIDS are both sexually transmitted diseases, and their transmission routes can be through sexual contact, mother-to-child transmission, and close living contact. The pathogens are different; gonorrhea is mainly caused by an infection of Neisseria gonorrhoeae leading to acute inflammation of the urogenital tract, while AIDS is a sexually transmitted disease caused by an HIV infection, which can affect various organs throughout the body.

When infected with one sexually transmitted disease, other pathogens can also infect simultaneously. Therefore, after diagnosing one sexually transmitted disease, it is important to check for the presence of other sexually transmitted diseases such as AIDS, genital warts, syphilis, etc., to see if there is a co-infection.