When is the best time to get a tetanus shot?

Written by Zhang Peng
General Surgery
Updated on March 17, 2025
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Tetanus infection carries a certain mortality rate, with current statistics indicating that the death rate from tetanus infection can reach around 40%. Typically, tetanus is caused by an acute, specific infection resulting from the growth and reproduction of Clostridium tetani in human wounds, which produce toxins. Generally, it can only grow and reproduce in an anoxic environment, so it is most commonly found in soil, human and animal feces, and rust. For wounds, especially sharp and deep cuts, it is usually vital to administer a tetanus shot promptly. The choices generally are tetanus immunoglobulin or tetanus antitoxin, which have different half-lives; tetanus antitoxin generally lasts about three days, whereas tetanus immunoglobulin can last up to three weeks. Therefore, in the presence of high-risk infection factors, it is advisable to administer the injection as soon as possible, generally recommended within 24 hours.

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Written by Liu Huan Huan
General Surgery
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How to rescue from tetanus allergy

In clinical settings, when administering tetanus injections, it is very easy for allergic reactions to occur, even severe complications like anaphylactic shock. In such cases, the following emergency measures can be taken: First, establish an intravenous access immediately, then start the patient on infusion therapy; Second, if the patient experiences a drop in blood pressure, vasopressor agents can be used for pressor therapy; Third, it's essential to provide the patient with cardiac monitoring, oxygenation, and other supportive treatments. In addition, it's crucial to use anti-allergy medications. There are many anti-allergic drugs available clinically, and the specific medication to be used should be decided based on the patient's specific condition. (Please administer medications under the guidance of a professional physician, and do not self-medicate.)

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Written by Ma Xian Shi
General Surgery
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Tetanus incubation period

Tetanus is a specific infection caused by Clostridium tetani. The incubation period of tetanus is generally seven to eight days, but it can be as short as 24 hours or as long as several months to years. Patients with shorter incubation periods have a worse prognosis. Tetanus occurs within two weeks after injury in 90% of patients, presenting symptoms such as general weakness, headache, dizziness, chewing difficulty, local muscle tightness, painful pulling, and increased reflexes. Typical symptoms include muscle tonic contraction, opisthotonus, and facial expressions characterized by lockjaw and a sardonic smile.

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Written by Tang Da Wei
General Surgery
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Is the risk of tetanus high?

Tetanus occurs infrequently, but once it appears, the condition can be very severe and may lead to death if not treated promptly. Tetanus infection is mainly caused by infection with the tetanus bacillus. The tetanus bacillus is an anaerobic bacterium that exists everywhere in nature. If the wound is very deep with a small surface area, and the conditions inside the wound become anaerobic, if the tetanus bacilli inside the wound are not thoroughly cleaned, it could lead to the rapid reproduction of the tetanus bacilli, releasing tetanus toxin and causing a tetanus infection in the patient.

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Written by Li Jin Quan
General Surgery
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How long is a tetanus shot effective?

Tetanus generally refers to a specific type of infection caused by the entry of tetanus bacillus into the body through broken skin or mucous membranes, where it produces a large amount of toxin. Typically, the incubation period for tetanus is 6 to 7 days, but it can be as short as within 24 hours or as long as several months or even years. Therefore, if there is a wound, the first thing to do is to clean the wound with hydrogen peroxide or saline. Then, it is best to go to the hospital to get a tetanus vaccine within 24 hours. If the tetanus vaccine is not administered within 24 hours, it can still be effective if given within a week.

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Written by Liu Huan Huan
General Surgery
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Can I get a tetanus shot in the evening?

If a patient has a relatively deep wound, such as reaching the subcutaneous fat layer or even more severely, the muscle layer, it is important to prevent tetanus infection. It is advised that the patient must come to the hospital for a tetanus antitoxin injection into the muscle. After an injury, the sooner the tetanus antitoxin is injected, the better, as delays can affect the effectiveness of the antitoxin. Therefore, tetanus antitoxin can also be administered at night. Generally, one should go to the emergency surgery department of the hospital for the injection, as the emergency surgery department is on duty 24 hours a day, so it is possible to receive the tetanus shot at night.