Tetanus prophylactic treatment is advised to be carried out as soon as possible, ideally within 24 hours for optimal effectiveness. However, prevention treatment can still be carried out after 24 hours, as long as the disease has not manifested. Current research does not prove that tetanus prevention is ineffective after this period. Therefore, timely and effective preventive treatment should be implemented following high-risk tetanus infection factors, choosing either tetanus antitoxin or tetanus immunoglobulin. The incubation period for tetanus infection is about a week, and as long as the disease has not manifested, choosing appropriate medication can have a preventive effect. Tetanus antitoxin and tetanus immunoglobulin have different metabolic cycles; the half-life of tetanus antitoxin is generally about three days, whereas tetanus immunoglobulin can last up to three weeks.