What is the function of a tetanus shot?

Written by Xu Jun Hui
General Surgery
Updated on January 01, 2025
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The function of the tetanus shot is to activate the body's immune system to produce antibodies that can specifically bind to the tetanus toxin, preventing the toxin from binding with nerve cells and causing a toxic reaction that could lead to respiratory arrest, asphyxiation, and endanger life safety. Tetanus infection occurs when the Clostridium tetani bacteria enter the body through mucous membranes following an injury, producing toxins that affect certain muscle groups, such as the jaw and respiratory muscles, thus threatening life safety. Therefore, the role of the tetanus shot is to produce antibodies that bind to the tetanus toxin, preventing it from producing a toxic reaction with nerve cells. Thus, if some wounds are deep and heavily contaminated, it is essential to undergo anti-tetanus treatment.

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Written by Li Jin Quan
General Surgery
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Does tetanus cause fever?

When tetanus occurs, early symptoms mainly include dizziness, headache, fatigue, decreased appetite, weak chewing, sore jaw muscles, or tense facial muscles. Some cases show exaggerated reflexes or muscle tension. Generally, tetanus has its typical manifestations, such as difficulty in opening the mouth, risus sardonicus (a sardonic smile), opisthotonus (arching of the back), and stiff neck. In clinical practice, a few cases may even have a fever. Therefore, fever in tetanus is only seen in individual cases.

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Written by Xu Jun Hui
General Surgery
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How many days after a tetanus shot should you not drink alcohol?

Tetanus injections are divided into tetanus toxoid, which requires a skin test, and tetanus immunoglobulin, which does not require a skin test. It is advised not to drink alcohol before receiving a tetanus toxoid injection, as alcohol can cause dilation of the capillaries throughout the body, leading to flushed skin, which can affect the outcome of the skin test and result in false positive or false negative results, impacting treatment. Wounds requiring tetanus injections are generally either very deep, severely contaminated, or involve an open fracture, typically indicating a severe wound. It is advised not to consume alcohol during the wound healing period to avoid delaying recovery. Therefore, alcohol should be avoided for 24 hours before the tetanus shot and during the subsequent recovery period of the wound.

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Written by Li Jin Quan
General Surgery
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How much is the tetanus serum?

When there is a potential risk of tetanus infection in our wounds, we should promptly receive a tetanus shot. The tetanus treatments commonly used today include tetanus antitoxin and tetanus immunoglobulin, also known as tetanus serum. Generally, the price of tetanus antitoxin is about seven to eight yuan each. Tetanus serum can be divided into two types: human tetanus immunoglobulin and horse tetanus immunoglobulin. The price of human tetanus immunoglobulin is slightly over 80 yuan, while horse tetanus immunoglobulin costs slightly over 30 yuan. Horse tetanus immunoglobulin requires a skin test before it can be administered.

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Written by Liu Huan Huan
General Surgery
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Is tetanus administered intramuscularly or subcutaneously?

Tetanus is widely used clinically and is known as tetanus antitoxin, intended solely to prevent the clinical symptoms caused by infection with Clostridium tetani. Therefore, a skin test must be conducted before administering tetanus injections. The common skin test involves creating a skin wheal intradermally; if the skin test is negative, one can proceed with the tetanus antitoxin injection. The injection can be administered intramuscularly or subcutaneously. For example, the common sites include the deltoid attachment area on the upper arm for subcutaneous injections, and the deltoid or the lateral part of the buttock for intramuscular injections, among others. These are the injection sites for tetanus.

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Written by Li Xiao Lin
Emergency Department
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Will tetanus cause muscle soreness?

Tetanus can cause muscle pain. The main symptoms of a tetanus attack include sudden onset, impaired consciousness, frothing at the mouth, limb convulsions, body stiffness, presenting in an opisthotonos posture, and concurrent incontinence of urine and feces, with the duration varying according to the condition. Because convulsions cause the muscles to be in a state of rigidity, this leads to muscle ischemia and hypoxia, thereby increasing lactic acid and causing this state of muscle pain. Therefore, during a tetanus attack, measures should be taken to control these convulsions. At the same time, use chopsticks to prop against the teeth to prevent biting the tongue and other such incidents. If the condition is severe, immediately call emergency services (120) to get to a hospital for urgent treatment.