What is the function of a tetanus shot?

Written by Xu Jun Hui
General Surgery
Updated on January 01, 2025
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The function of the tetanus shot is to activate the body's immune system to produce antibodies that can specifically bind to the tetanus toxin, preventing the toxin from binding with nerve cells and causing a toxic reaction that could lead to respiratory arrest, asphyxiation, and endanger life safety. Tetanus infection occurs when the Clostridium tetani bacteria enter the body through mucous membranes following an injury, producing toxins that affect certain muscle groups, such as the jaw and respiratory muscles, thus threatening life safety. Therefore, the role of the tetanus shot is to produce antibodies that bind to the tetanus toxin, preventing it from producing a toxic reaction with nerve cells. Thus, if some wounds are deep and heavily contaminated, it is essential to undergo anti-tetanus treatment.

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Where can you get a tetanus shot?

General hospitals or surgical clinics are suitable; first and foremost, tetanus vaccines are for the prevention of tetanus, especially for deep wounds. Therefore, once an injury occurs, it is advised to visit a surgical clinic promptly to complete relevant examinations and undergo wound cleaning and disinfection. If necessary, oral antibiotics such as cephalosporins should be taken. Additionally, a tetanus vaccine must be administered within 24 hours to prevent tetanus. Afterwards, rest and proper diet are important; avoid spicy and irritating foods, consume high-protein foods, and ensure regular follow-up examinations.

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How to administer a tetanus shot if it is negative?

A negative tetanus needle test indicates that the patient is not allergic to the tetanus antitoxin and can continue with intramuscular injections, typically administered in the upper arm or buttock muscles, in doses ranging from 1000 to 3000 units each time. If the infection is severe or the tetanus injection is not timely, the dosage may be appropriately increased, generally by one to two times. The purpose of administering tetanus antitoxin treatment is to prevent infection by Clostridium tetani, an anaerobic bacterium. For patients with deep wounds or heavily contaminated wounds, such as those contaminated with soil or rust, Clostridium tetani can easily colonize. Therefore, for such patients, it is essential to perform tetanus antitoxin treatment while cleaning and dressing the wound.

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Do you get a fever during the early stages of tetanus?

Tetanus symptoms can potentially begin with a fever during the early stage, generally occurring between six and ten days after injury, meaning symptoms can appear within 24 hours or several weeks post-injury. The shorter the incubation period, the more severe the symptoms and the higher the risk. Some patients may experience fatigue, headache, dizziness, restlessness, and possibly fever. Subsequently, typical symptoms of tetanus occur, primarily characterized by intense muscle contractions starting with the facial muscles. This includes difficulties in opening the mouth and lockjaw, among others. Thus, prevention is crucial for tetanus. When there is a local tissue injury, it is essential to promptly disinfect with hydrogen peroxide or iodine, followed by cleaning and suturing the wound and timely tetanus vaccination to prevent the disease.

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Does a tetanus shot stimulate the brain?

Tetanus shot, if administering tetanus toxoid, a skin test is required before injection. If the skin test is negative and there is no allergy, then the injection can proceed without stimulating the brain. A small proportion of patients undergoing anti-tetanus treatment might experience some uncomfortable reactions, commonly allergies, fever, and symptoms of vomiting. Generally, these can be alleviated with rest or symptomatic treatment. Only less than 1% of patients may experience seizures or coma, which are very rare reactions. If such reactions occur, it is urgent to go to a formal hospital for symptomatic and supportive treatment. For the vast majority of tetanus shots, if administered in a formal hospital and the patient has a negative skin test, or if given tetanus immunoglobulin, it does not stimulate the brain.

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Tetanus allergic symptoms

The primary allergic reaction to tetanus is anaphylactic shock. Some patients may experience skin redness, itching, chest tightness, difficulty breathing, pale complexion, and cold sweats within minutes after receiving the tetanus vaccine. Some may also experience nausea, vomiting, and even abdominal pain. Additionally, blood pressure may drop, and the pulse may slow down. In severe cases, coma can occur, and even cessation of heartbeat and breathing. The second type of allergic reaction is serum sickness, which can occur after a tetanus injection, characterized by erythema, edema, and itching at the injection site.