How much is the tetanus serum?

Written by Li Jin Quan

General Surgery

Updated on September 29, 2024

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When there is a potential risk of tetanus infection in our wounds, we should promptly receive a tetanus shot. The tetanus treatments commonly used today include tetanus antitoxin and tetanus immunoglobulin, also known as tetanus serum. Generally, the price of tetanus antitoxin is about seven to eight yuan each. Tetanus serum can be divided into two types: human tetanus immunoglobulin and horse tetanus immunoglobulin. The price of human tetanus immunoglobulin is slightly over 80 yuan, while horse tetanus immunoglobulin costs slightly over 30 yuan. Horse tetanus immunoglobulin requires a skin test before it can be administered.

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Written by Zhang Peng

General Surgery

1min

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How many times do you need to get a tetanus shot?

The number of tetanus shots required depends on the specific condition of the wound and the patient's previous immunization history. Generally, for smaller, superficial, and cleaner wounds, which are considered to have a low risk of tetanus infection, the body can produce protective antibodies on its own. In such cases, a tetanus toxoid injection is given once a month, usually three times in total, allowing the patient's body to produce active antibodies and obtain long-term protection. If the wound is large, deep, and contaminated, with a substantial amount of foreign material or necrotic tissue, the chances of tetanus infection are very high. In such cases, passive immunization is actively conducted, usually involving tetanus antitoxin or immunoglobulin. Here, typically three doses of tetanus toxoid are administered to stimulate the body to produce active antibodies and achieve long-term protection.

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Written by Zhang Peng

General Surgery

59sec

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How long does the tetanus shot last?

The duration of the effectiveness of a tetanus shot depends on whether tetanus antitoxin or tetanus immunoglobulin is administered following a suspected tetanus infection. Both types are forms of artificial passive immunity, providing immediate specific immunity after injection, mainly for treatment or emergency prevention. The metabolism and immune duration of these two injections vary: generally, tetanus antitoxin lasts about seven days, while tetanus immunoglobulin can last up to three weeks. Therefore, the specific duration of the effectiveness of a tetanus shot must be determined based on the individual injection circumstances. For suspected tetanus infections, it is generally advised to administer the injection as soon as possible. It's not that the injection will be ineffective if administered after a certain time, but rather that effective prevention before the onset of the disease can still be beneficial.

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Written by Li Jin Quan

General Surgery

36sec

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Does tetanus cause fever?

When tetanus occurs, early symptoms mainly include dizziness, headache, fatigue, decreased appetite, weak chewing, sore jaw muscles, or tense facial muscles. Some cases show exaggerated reflexes or muscle tension. Generally, tetanus has its typical manifestations, such as difficulty in opening the mouth, risus sardonicus (a sardonic smile), opisthotonus (arching of the back), and stiff neck. In clinical practice, a few cases may even have a fever. Therefore, fever in tetanus is only seen in individual cases.

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Written by Li Jin Quan

General Surgery

36sec

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How long does it take for tetanus to develop?

Tetanus is a specific type of infection caused by the toxin produced by the growth and reproduction of Clostridium tetani, which enters the body through damaged skin and mucous membranes and thrives in an anaerobic environment. Clinically, it is mainly characterized by lockjaw, muscle rigidity, and muscle spasms. After being infected with tetanus, people generally show symptoms within seven to eight days; in quick cases, symptoms can appear within twenty-four hours, while in longer scenarios, the onset can take several months or even years.

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Written by Gao Sen

General Surgery

53sec

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The likelihood of a wound being infected with tetanus

Tetanus is a specific infection often associated with trauma, with a high contamination rate of tetanus bacillus in traumatic wounds. On the battlefield, the contamination rate can reach 25% to 80%, although the incidence of tetanus in contaminated wounds is only about 10% to 20%. This suggests that other factors are necessary for the disease to occur, with the main factor being an anaerobic environment. If the wound is deep, with a small external opening, and contains necrotic tissue, blood clots, or is too tightly packed, this can lead to local ischemia. Additionally, if there is a co-infection with aerobic bacteria consuming residual oxygen in the wound, it creates an anaerobic environment conducive to the growth of the bacteria, thus increasing the likelihood of tetanus infection in the wound.