How many times do you need to get a tetanus shot?

Written by Xu Jun Hui
General Surgery
Updated on February 19, 2025
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If tetanus vaccination is required due to an injury, one injection is sufficient. There are two types of tetanus shots. One is called tetanus antitoxin, which is extracted from horse serum. For this, a skin test is needed to check for allergies. If allergic, tetanus antitoxin cannot be used; if not, it can be used. The other type is refined tetanus antitoxin, also known as tetanus immune globulin, extracted from human serum. This type does not require a skin test and can be used directly, but it is more expensive than tetanus antitoxin. If tetanus treatment is needed for each injury, one injection is sufficient.

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Is tetanus serious?

Firstly, it must be acknowledged that tetanus is a curable, specific infectious disease. When the human body is infected with tetanus, the initial symptoms mainly include dizziness, headache, fatigue, decreased appetite, difficulty in chewing, muscle soreness, or some heightened reflexes. As the condition worsens, muscle spasms and rigidity can occur, such as grimacing, lockjaw, difficulty opening the mouth, stiff neck, and opisthotonos. In severe cases, there may be difficulty breathing, respiratory arrest, and even cardiac arrest. If someone is suffering from tetanus, they should promptly seek systematic and formal treatment at a hospital. As long as there are no serious complications, the vast majority of tetanus patients can be cured, so tetanus is not as frightening as it may seem.

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Tetanus incubation period

Tetanus is a specific infection caused by Clostridium tetani. The incubation period of tetanus is generally seven to eight days, but it can be as short as 24 hours or as long as several months to years. Patients with shorter incubation periods have a worse prognosis. Tetanus occurs within two weeks after injury in 90% of patients, presenting symptoms such as general weakness, headache, dizziness, chewing difficulty, local muscle tightness, painful pulling, and increased reflexes. Typical symptoms include muscle tonic contraction, opisthotonus, and facial expressions characterized by lockjaw and a sardonic smile.

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What should I do if I drink alcohol with tetanus?

If there are high risk factors for tetanus infection after an injury, and alcohol has been consumed, it is generally advisable to wait until sobriety before conducting relevant skin tests. Currently, there is no clear research on the relationship between alcohol consumption and an allergy to tetanus antitoxin. It is not very clear whether alcohol impacts the results of a skin test, so it is safer to perform the test after sobering up. Since the consequences of a tetanus infection can be severe, and the tetanus injection itself carries a certain risk of anaphylactic shock, which can lead to multiple organ problems and even be life-threatening, it is generally safer to conduct the skin test after sobering up and then proceed with the timely injection treatment. If the skin test is positive, tetanus immunoglobulin should be chosen promptly.

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What should I do if I am allergic to tetanus shots?

The full name of the tetanus shot is tetanus antitoxin serum, which is mainly made from horse serum and has certain allergenic properties. If a patient is allergic to tetanus antitoxin serum, desensitization injections can be used, which involves gradually injecting one milliliter of the tetanus antitoxin serum into the body in four or more sessions, with each injection spaced about twenty to thirty minutes apart. After each injection, it is important to closely observe the patient's reaction, including checking for signs of itching in the nose, hives throughout the body, or difficulty breathing. If any of these symptoms occur, emergency treatment should be administered. If the injections of tetanus antitoxin serum cannot be completed multiple times, or if the patient is unwilling to accept this method of injection, tetanus immunoglobulin can be administered instead of tetanus antitoxin serum. Tetanus immunoglobulin does not require a sensitivity test and can be directly injected into the body without causing an allergic reaction, although it is more expensive.

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Can tetanus be treated?

Tetanus is a specific infectious disease, most cases of which present as muscle tension and rigidity. Specific symptoms include difficulty opening the mouth, a sardonic smile, stiff neck, and opisthotonus. In severe cases, difficulties in breathing or even cessation of breathing can occur, and in critical cases, the heartbeat may also stop. Once tetanus occurs, it is crucial to seek active treatment at a hospital. With proper and systematic treatment provided by hospitals, most patients can be cured. Therefore, tetanus is a curable infectious disease.