Whooping cough is an acute respiratory infectious disease caused by Bordetella pertussis infection, commonly seen in children. The main clinical symptoms include typical paroxysmal spasmodic cough, crowing inspiratory whoop, with the cough being more prominent at night. In the peripheral blood, there will be a marked increase in white blood cell count, lymphocyte count, and lymphocyte classification. After a confirmed diagnosis of whooping cough, macrolide antibiotics are administered. After a week of aggressive treatment, the blood count typically decreases significantly.