Can whooping cough recover without treatment? There is individual variation in clinical cases. If the patient has mild symptoms, it is possible for them to recover on their own without treatment. If the symptoms are more typical, timely anti-inflammatory treatment is necessary; otherwise, it may lead to other complications. If there are no complications and the immune system is normal, natural recovery may also be possible, but the duration of the illness will likely be longer. Treatment decisions should primarily consider the patient's resistance and general physique. From a health perspective, once diagnosed, it is necessary to promptly use macrolide antibiotics to eliminate the Bordetella pertussis bacteria.