Pertussis, commonly known as whooping cough, is a contagious respiratory disease often seen in children. It is typically caused by infection with the Bordetella pertussis or Corynebacterium diphtheriae bacteria, and is mainly transmitted through airborne droplets and close contact with infected individuals. It has a strong contagion potential, with contagiousness becoming significant about two to three weeks from the incubation period to the onset of symptoms. Once diagnosed, it is crucial to isolate the patient promptly and administer medications to alleviate discomfort. Diagnosis is usually confirmed through the cultivation of the pathogen. Treatment includes medications to thin the mucus, isolation of the infectious source, and the use of macrolide antibiotics like erythromycin or azithromycin to manage inflammation during the acute phase.