Can colorectal cancer be inherited?

Written by Zhang Peng
General Surgery
Updated on January 25, 2025
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Can rectal cancer be inherited? Rectal cancer is a relatively common type of malignant tumor in the rectum. Genetic factors are among the causes of rectal cancer, but they are not absolute. The proportion of genetic factors in the occurrence of rectal cancer is relatively small. Most causes are related to inhalative lesions of the rectum, and also linked to the patient's lifestyle, bowel habits, etc., which can lead to the occurrence of rectal cancer. So, there is a genetic component, but the likelihood is low. Therefore, for patients with familial hereditary diseases or families where multiple people have rectal cancer, it is important to conduct timely re-examinations with colonoscopies or to perform some genetic screening.

Other Voices

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Written by Gong Chun
Oncology
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What are the symptoms and early signs of rectal cancer?

In the early stages of rectal cancer, there are no obvious symptoms. Only when the condition progresses to a certain extent do some clinical symptoms appear. The first is a change in bowel habits or the nature of the stool. The second possible symptom is abdominal pain. The third possible outcome is intestinal obstruction. The fourth symptom occurs when the tumor develops to a certain extent, and lumps can be felt in the abdomen. The fifth point includes possible symptoms of systemic poisoning such as anemia, weight loss, fever, and weakness. The sixth point is that in the advanced stages of rectal cancer, some metastatic lesions may appear, such as extensive pelvic metastasis and infiltration, leading to pain in the sacral area and sciatic neuralgia; if areas like the vaginal, rectal mucosa, or bladder mucosa are involved, there may be vaginal bleeding or blood in the urine, resulting in conditions like rectovaginal or rectovesical fistulas.

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Written by Yu Xu Chao
Colorectal Surgery
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How to differentiate rectal cancer from hemorrhoids

Rectal cancer is a malignant lesion, with clinical symptoms mainly causing an increase in the frequency of bowel movements, changes in stool characteristics such as grooved stools or stools with mucus and pus and blood. Severe patients may experience abdominal pain, weight loss, anemia, and other accompanying symptoms. Generally, low-lying rectal cancer can be seen during a digital rectal examination or with an anoscope. If the cancer is located higher up, an electronic colonoscopy is needed to see the cauliflower-like mass. Hemorrhoids, on the other hand, are benign lesions often caused by improper diet or poor bowel habits, leading to pathological hypertrophy and descent of the anal cushions. They are mostly characterized by intermittent painless rectal bleeding with bright red blood, along with a feeling of heaviness and a foreign body sensation in the anus.

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Written by Yu Xu Chao
Colorectal Surgery
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Does rectal cancer vomit infect others?

Rectal cancer vomiting is not contagious. The vomiting in rectal cancer is primarily due to the growth of a tumor in the intestine that becomes too large, which then induces intestinal obstruction, causing the patient to vomit and be unable to eat. Furthermore, the vomit is not contagious, and rectal cancer itself is not a contagious disease. For patients with rectal cancer, it is essential to relieve the obstruction as soon as possible and to arrange surgery promptly. If sphincter preservation is possible, it should be attempted. Also, patients with rectal cancer should undergo a pathological biopsy to determine the type of cancer and whether it has spread. Patients with rectal cancer also need to be on a full-liquid diet. Foods with residues should be avoided as much as possible to not easily induce intestinal obstruction, leading to electrolyte disturbances or even causing the body to go into shock. Thus, it is crucial to pay sufficient attention to these issues.

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Written by Deng Heng
Colorectal Surgery
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Can you eat edamame after rectal cancer surgery?

Patients with rectal cancer can eat edamame after surgery. However, they should pay attention to the following dietary advice post-surgery: First, eat less or avoid animal fats, which means limiting the intake of saturated fatty acids. Second, even the consumption of vegetable oils should be limited. Third, do not eat fried foods. Fourth, during cooking, oils should not be overheated. Fifth, eat plenty of fresh vegetables and fruits.

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Written by Yan Chun
Oncology
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What are the late-stage symptoms of rectal cancer?

The late-stage symptoms of rectal cancer patients in clinical practice mainly include the following types. The first type is abdominal symptoms caused locally by rectal cancer. For example: bloody stools, pass stools with mucous and pus, anal pain, bloating, abdominal pain, and other manifestations. The second category of symptoms is those from metastases in various locations. For example, bone metastases cause bone pain and limb movement disorders. Lung metastases cause chest tightness, shortness of breath after activity, chest pain, breathing difficulties, coughing and coughing up blood, etc. Brain metastases cause headaches, dizziness, and seizures. The third category of symptoms is mainly systemic symptoms caused by rectal cancer lesions, such as: weight loss, fatigue, and high fever.