Is hepatitis B cirrhosis contagious?

Written by Zhang Jian Kang
Infectious Disease
Updated on September 08, 2024
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If hepatitis B is not well controlled, it can easily lead to the occurrence of cirrhosis. After the hepatitis B virus infects the human body, it causes repeated inflammatory damage to the liver, with recurring abnormalities in liver function. If during this period there is no formal antiviral treatment or lack of attention, it is very likely to lead to the development of cirrhosis. Once cirrhosis from hepatitis B occurs, it is generally irreversible. Cirrhosis due to hepatitis B is also an infectious disease, and its level of infectiousness mainly depends on the presence of the virus. If the viral load is positive, indicated by a positive HBV-DNA test, then it is infectious. If HBV-DNA is negative, then it is not infectious. Therefore, whether cirrhosis from hepatitis B is infectious primarily depends on the level of HBV-DNA.

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What are the gastrointestinal symptoms of cirrhosis?

In the early stages of cirrhosis, many patients do not exhibit any symptoms, but some may experience fatigue, nausea, vomiting, poor appetite, and indigestion. Some patients might also suffer from portal hypertensive gastropathy due to cirrhosis, leading to symptoms such as pain and bloating in the upper abdomen, acid reflux, and belching. If the disease progresses to the decompensated stage of cirrhosis, portal hypertension can cause varices in the esophagus and stomach, which may lead to severe upper gastrointestinal bleeding if hard food is consumed. Symptoms can include vomiting dark red blood or fresh blood, dizziness, fatigue, and cold sweats. In such cases, it is advised to seek immediate medical attention for emergency treatment.

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Written by Yuan Lin Yan
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Is hepatitis B with liver cirrhosis severe?

Hepatitis B-related cirrhosis is a form of liver cirrhosis caused by the hepatitis B virus, and it is more severe than chronic hepatitis B. However, cirrhosis can be categorized into compensated cirrhosis and decompensated cirrhosis. Decompensated cirrhosis refers to the advanced stages of cirrhosis, characterized by significant hardening of the liver, and complications such as ascites, hepatic encephalopathy, and gastrointestinal bleeding may occur. This type of cirrhosis is severe and has a high mortality rate, and even timely antiviral therapy against hepatitis B cannot effectively delay the progression of the disease. Compensated cirrhosis refers to the early stages of cirrhosis, where complications like ascites, hepatic encephalopathy, and gastrointestinal bleeding are not present, making this type of cirrhosis comparatively less severe. With timely antiviral therapy against hepatitis B, the progression of cirrhosis can be delayed.

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Written by Wu Hai Wu
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Is early-stage cirrhosis treatable?

Whether early symptoms of cirrhosis can be treated depends on the cause of the cirrhosis. If the cause of the cirrhosis is clear and can be effectively suppressed, then the early symptoms of cirrhosis can be effectively treated. For example, if the cirrhosis is caused by chronic hepatitis B virus infection, then the use of antiviral drugs such as entecavir, tenofovir, and adefovir can effectively control the further development of cirrhosis. However, if the cirrhosis is caused by autoimmune liver diseases or cholestatic liver cirrhosis, the treatment might not be as effective, because there are no specifically effective treatments available for these diseases. (Medication should be used under the guidance of a physician)

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Written by Ye Xi Yong
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How long can one live with hepatitis B-related cirrhosis?

We cannot give a definite answer on how long a patient with hepatitis B-related cirrhosis can live, as the life expectancy in late-stage cirrhosis is influenced by many factors including treatment measures, lifestyle adjustments, daily healthcare, and physical condition. Patients in the compensated stage of cirrhosis, if treated and the progression of cirrhosis is halted, with normal liver function and negative hepatitis B virus replication indicators, can work normally. In this state, the quality of life is good, and they can live to 70 to 80 years old. For patients in the decompensated stage of cirrhosis, if untreated and the cirrhosis is allowed to progress, about 70 to 80% may die within 5 years; however, aggressive treatment, including traditional Chinese medicine for liver fibrosis and cirrhosis, combined with antiviral treatment, bleeding prevention, liver protection, and liver transplantation, can significantly increase the survival time of patients.

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Symptoms of decompensated cirrhosis due to hepatitis B

Hepatitis B virus infection repeatedly leads to severe damage to the liver. If chronic hepatitis is not actively controlled, cirrhosis may occur. A symptom of decompensated cirrhosis mainly manifests as ascites, gastrointestinal bleeding, portal hypertension, and some people exhibit symptoms of hepatic encephalopathy. The presence of these complications indicates that the patient has reached the stage of decompensated cirrhosis. Patients in this stage often exhibit distinct jaundice, dark urine, abdominal distension after eating, and the presence of ascites with a positive shifting dullness. Additionally, some patients may experience vomiting blood, black stools, liver coma, and other related symptoms. Once these symptoms appear, it indicates that the prognosis for the patient is relatively poor.