How long can one live with hepatitis B-related cirrhosis?

Written by Ye Xi Yong
Infectious Diseases
Updated on September 16, 2024
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We cannot give a definite answer on how long a patient with hepatitis B-related cirrhosis can live, as the life expectancy in late-stage cirrhosis is influenced by many factors including treatment measures, lifestyle adjustments, daily healthcare, and physical condition. Patients in the compensated stage of cirrhosis, if treated and the progression of cirrhosis is halted, with normal liver function and negative hepatitis B virus replication indicators, can work normally. In this state, the quality of life is good, and they can live to 70 to 80 years old. For patients in the decompensated stage of cirrhosis, if untreated and the cirrhosis is allowed to progress, about 70 to 80% may die within 5 years; however, aggressive treatment, including traditional Chinese medicine for liver fibrosis and cirrhosis, combined with antiviral treatment, bleeding prevention, liver protection, and liver transplantation, can significantly increase the survival time of patients.

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Which is more serious, liver failure or cirrhosis?

Liver failure refers to a functional impairment of the liver, which could be acute or chronic damage. For instance, it could be the end stage of chronic liver disease, or an acute condition such as hepatitis, or another acute liver lesion. Other common lesions may also cause a sudden abnormality in liver function, resulting in severe liver dysfunction. At this point, liver cirrhosis is a common cause of liver failure. For example, in the middle and late stages of liver cirrhosis, liver function is completely decompensated, meaning the liver can no longer maintain its basic normal functions, leading to liver failure. Therefore, liver failure is one of the major consequences of liver cirrhosis, but the two are distinct. Liver failure can also be caused by other reasons not related to cirrhosis. For example, acute ischemia in the liver, such as in shock patients, can lead to liver ischemia and subsequently liver failure. Liver cirrhosis is just one of the common causes thereof.

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Can liver cirrhosis be detected by an ultrasound B-scan?

Liver cirrhosis can be diagnosed with an ultrasound. In the early stages of cirrhosis, there are no specific changes in the sonographic pattern visible on ultrasound. Typically, cirrhosis manifests as a decrease in liver volume, with imbalanced proportions of the liver lobes; both the left and right lobes may shrink, with compensatory hypertrophy observed in some cases in the left lobe. The liver capsule appears serrated, and the echoes from the liver area are coarser and stronger, with uneven distribution. It's possible to observe nodules with low or high echoes. The liver vessels vary in thickness, the hepatic veins may narrow, and the portal vein can widen. An enlarged portal vein can lead to symptoms like splenomegaly and ascites.

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Can alcoholic liver cirrhosis be cured?

Cirrhosis caused by alcohol can be treated clinically. The first and foremost treatment for alcoholic cirrhosis is abstinence from alcohol. If one cannot abstain, no treatment will achieve the desired effect or be of much use. Once cirrhosis has developed, the condition cannot be reversed; it can only be managed with medications to slow the progression of the cirrhosis and reduce the occurrence of complications. If financial circumstances allow, a liver transplant can be considered for treatment. Naturally, alcoholic cirrhosis can also be treated with a liver transplant. Thus, alcoholic cirrhosis is a treatable condition.

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Is the pain obvious in the early stages of cirrhosis?

In the early stages of cirrhosis, the pain is not very obvious. Patients in the early stages of cirrhosis may experience vague discomfort in the upper right abdomen, while others may never experience pain at all. Those in the early stages may also have symptoms such as belching, fatigue, acid reflux, jaundice, and dark urine. Further comprehensive auxiliary examinations are needed, such as liver function tests and abdominal imaging studies. At the same time, it is important to identify the cause of early-stage cirrhosis in patients as soon as possible and adopt appropriate treatment measures based on different causes. For instance, if it is caused by alcohol, then treatment should involve abstaining from alcohol.

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Symptoms of decompensated cirrhosis due to hepatitis B

Hepatitis B virus infection repeatedly leads to severe damage to the liver. If chronic hepatitis is not actively controlled, cirrhosis may occur. A symptom of decompensated cirrhosis mainly manifests as ascites, gastrointestinal bleeding, portal hypertension, and some people exhibit symptoms of hepatic encephalopathy. The presence of these complications indicates that the patient has reached the stage of decompensated cirrhosis. Patients in this stage often exhibit distinct jaundice, dark urine, abdominal distension after eating, and the presence of ascites with a positive shifting dullness. Additionally, some patients may experience vomiting blood, black stools, liver coma, and other related symptoms. Once these symptoms appear, it indicates that the prognosis for the patient is relatively poor.