Causes of cervical cancer

Written by Xu Xiao Ming
Obstetrics and Gynecology
Updated on February 01, 2025
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There are several causes of cervical cancer, such as having multiple sexual partners, premature birth, smoking, and early sexual activity, all of which could lead to cervical cancer. However, the main cause of cervical cancer is infection with HPV, the human papillomavirus. It has been scientifically proven that cervical cancer is caused by HPV infection. Therefore, this viral infection is the primary cause of cervical cancer. It is recommended that women of childbearing age undergo cervical cancer screening to check for any abnormalities in the cervix.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Can cervical cancer be cured?

Cervical cancer can be treated with options including surgery, radiotherapy, and chemotherapy. For Stage 1A1 cervical cancer, a conization surgery can be chosen; for stages from 1A2 up to before 2B, a radical hysterectomy with bilateral adnexectomy and pelvic lymphadenectomy can be selected; if it is Stage 2B, where the cancer has spread to the parametrium, it is recommended to first undergo chemotherapy as preoperative neoadjuvant therapy to reduce the tumor size before proceeding with surgery; if the cancer has progressed to Stage 3A1 and beyond, radiotherapy or chemotherapy is recommended. In summary, surgical treatment can be chosen for cervical cancer before Stage 2B; if it is Stage 2B or later, involving the parametrium or the lower third of the vagina, surgery is generally not an option, and the treatment usually involves radiotherapy or chemotherapy.

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Written by Gong Chun
Oncology
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Why would someone get cervical cancer?

Why does cervical cancer occur? There are several reasons for cervical cancer: The first is infection with the human papillomavirus, also known as HPV infection, which is the fundamental cause of precancerous lesions and cervical cancer. Secondly, there are other factors; in a few cases, HPV DNA is not detected in the tumor tissue, especially among elderly patients, and it is related to early childbirth and multiple pregnancies. The third point is that cervical cancer incidence is associated with high-risk males, including those who have had penile cancer, prostate cancer, or are high-risk individuals for cervical cancer. Women who are in contact with these high-risk men are more likely to develop cervical cancer. Lastly, irregular diet and lifestyle, along with smoking and drinking, can suppress the body's immune function, potentially promoting cancer.

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Written by Yan Chun
Oncology
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Will anything grow on the cervix in the early stages of cervical cancer?

In the early stages of cervical cancer, a minority of patients may develop growths on the cervix, but most exhibit erosive changes or thickening of the cervix. Early-stage cervical cancer generally involves a small area of cancerous tissue, with localized lesions and shallow infiltration depth. Many symptoms manifest as recurrent cervical erosion that is difficult to heal completely. There are also a few cases where small nodular lesions appear on the cervix. These small nodules generally do not cause significant damage to the cervix and present with mild clinical symptoms. Many patients only experience mild vaginal bleeding and discharge, with rare occurrences of pain, fever, general fatigue, weight loss, or other systemic symptoms in clinical settings.

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Written by Gong Chun
Oncology
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Late-stage symptoms of cervical cancer

What are some symptoms of late-stage cervical cancer? First, there may be vaginal bleeding, characterized by irregular vaginal bleeding. The amount of bleeding varies depending on the size of the lesion and the invasion of interstitial blood vessels. In the late stages, as major blood vessels may be eroded, significant bleeding can occur. The second symptom is vaginal discharge, which is often increased and may be white or blood-stained. Third, late-stage symptoms may include secondary symptoms such as involvement of adjacent tissues and organs and affected nerves, leading to frequent urination, urgency, constipation, swelling and pain in the lower limbs. Cancer pressing on the ureters can cause obstruction of the ureters, hydronephrosis, and uremia. Late stages may also present with symptoms of systemic failure such as anemia and cachexia.

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Written by Gong Chun
Oncology
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How is cervical cancer treated?

Cervical cancer is one of the malignant gynecological tumors. The treatment approach should be based on a comprehensive assessment of the disease stage, the hospital's facilities, and the patient's condition, among other factors, to develop an integrated treatment plan. The principle of cervical cancer treatment primarily involves surgery and radiotherapy, supplemented by chemotherapy as an integrated treatment plan. The treatment should consider clinical staging, age, general condition, and the overall level of technology and equipment to develop an appropriate treatment method. It is important to focus on personalized treatment and the initial treatment.