Causes of cervical cancer

Written by Xu Xiao Ming
Obstetrics and Gynecology
Updated on February 01, 2025
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There are several causes of cervical cancer, such as having multiple sexual partners, premature birth, smoking, and early sexual activity, all of which could lead to cervical cancer. However, the main cause of cervical cancer is infection with HPV, the human papillomavirus. It has been scientifically proven that cervical cancer is caused by HPV infection. Therefore, this viral infection is the primary cause of cervical cancer. It is recommended that women of childbearing age undergo cervical cancer screening to check for any abnormalities in the cervix.

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Written by Gong Chun
Oncology
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Cervical cancer leukorrhea characteristics

The characteristics of vaginal discharge in cervical cancer may include the presence of blood in the discharge. This is because cervical cancer often leads to increased vaginal discharge, which may also increase in quantity and might contain streaks of blood or bloody material. The discharge could be thin and watery or resemble rice wash water, and it might have a foul smell. In advanced stages, due to necrosis of the cancer tissue accompanied by infection, there can be a substantial amount of foul-smelling, purulent discharge resembling rice wash water. Therefore, these characteristics of the vaginal discharge are specific symptoms of cervical cancer. If such symptoms occur, it is crucial to seek medical consultation promptly to evaluate for cervical cancer.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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How is cervical cancer screened?

Cervical cancer screening is a routine gynecological examination item for married women and women who are sexually active. Cervical cancer screening includes TCT (ThinPrep Cytologic Test) and HPV (Human Papillomavirus) tests. The TCT is a cytological examination of the cervix to determine if there are any cervical lesions based on cell morphology. HPV is the human papillomavirus, and its presence is a high-risk factor for cervical cancer. Therefore, cervical cancer screening consists of both TCT and HPV tests. If abnormalities are found in either test, a cervical biopsy may be necessary to confirm the presence of cervical lesions. It is best to conduct these tests between three to seven days after the end of menstruation.

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Written by Gong Chun
Oncology
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Late-stage symptoms of cervical cancer

What are some symptoms of late-stage cervical cancer? First, there may be vaginal bleeding, characterized by irregular vaginal bleeding. The amount of bleeding varies depending on the size of the lesion and the invasion of interstitial blood vessels. In the late stages, as major blood vessels may be eroded, significant bleeding can occur. The second symptom is vaginal discharge, which is often increased and may be white or blood-stained. Third, late-stage symptoms may include secondary symptoms such as involvement of adjacent tissues and organs and affected nerves, leading to frequent urination, urgency, constipation, swelling and pain in the lower limbs. Cancer pressing on the ureters can cause obstruction of the ureters, hydronephrosis, and uremia. Late stages may also present with symptoms of systemic failure such as anemia and cachexia.

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Written by Gong Chun
Oncology
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Precursors of cervical cancer

The occurrence and development of the cervix is a process from quantitative to qualitative change, evolving gradually to a sudden shift over a long period. The precursor might be the heterotypic zone of the cervix, which is a common site for abnormalities. During the formation of this heterotypic zone, cervical epithelial metaplasia is relatively active, and, compounded by infection with the human papillomavirus and further stimulated by external carcinogens, immature or proliferative squamous epithelial cells may exhibit gradual changes or atypical hyperplasia, potentially leading to sarcomatoid changes in the cervical epithelium. This might be a precursor sign.

doctor image
home-news-image
Written by Xu Xiao Ming
Obstetrics and Gynecology
36sec home-news-image

Causes of cervical cancer

There are several causes of cervical cancer, such as having multiple sexual partners, premature birth, smoking, and early sexual activity, all of which could lead to cervical cancer. However, the main cause of cervical cancer is infection with HPV, the human papillomavirus. It has been scientifically proven that cervical cancer is caused by HPV infection. Therefore, this viral infection is the primary cause of cervical cancer. It is recommended that women of childbearing age undergo cervical cancer screening to check for any abnormalities in the cervix.