Cervical cancer indicators

Written by Gong Chun
Oncology
Updated on September 10, 2024
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The main indicators of cervical cancer are still the examination of the cervix and cervical canal tissues. There are obvious cancerous changes, and under the microscope pathological sections can show tendencies of cell carcinogenesis, or already developed cancer. The second is the cytological examination of cervical scrapings, which detects the presence of cancer cells. The third is the iodine test, where areas that do not stain after iodine staining indicate a lack of glycogen in the epithelium, suggesting possible lesions. The fourth is colposcopy, which may reveal suspicious cancerous areas, allowing for biopsy to confirm cancer cells. The fifth includes ultrasound, CT, MRI, etc., which can detect mass occupying lesions, all of which are indicators of cervical cancer. Of course, abnormalities in tumor markers are also considered, but the main reliance is still on the indicators from pathological examinations to determine if it's cervical cancer.

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Written by Li Shun Hua
Obstetrics and Gynecology
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There are several types of cervical cancer vaccines.

There are three types of cervical cancer vaccines: bivalent, quadrivalent, and nonavalent, and the recommended vaccination ages vary for each. The bivalent cervical cancer vaccine is suitable for females aged 9 to 45; the quadrivalent vaccine is suitable for females aged 20 to 45; the nonavalent vaccine is suitable for females aged 16 to 26. Vaccinations can be scheduled at hospitals within these age ranges. The younger the age at vaccination, the higher the antibody production after receiving the cervical cancer vaccine, meaning the effectiveness is better.

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Written by Liu Jian Wei
Obstetrics and Gynecology
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How is cervical cancer screened?

Cervical cancer screening is a routine gynecological examination item for married women and women who are sexually active. Cervical cancer screening includes TCT (ThinPrep Cytologic Test) and HPV (Human Papillomavirus) tests. The TCT is a cytological examination of the cervix to determine if there are any cervical lesions based on cell morphology. HPV is the human papillomavirus, and its presence is a high-risk factor for cervical cancer. Therefore, cervical cancer screening consists of both TCT and HPV tests. If abnormalities are found in either test, a cervical biopsy may be necessary to confirm the presence of cervical lesions. It is best to conduct these tests between three to seven days after the end of menstruation.

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Written by Gong Chun
Oncology
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Late-stage symptoms of cervical cancer

The symptoms of advanced cervical cancer start with vaginal bleeding. In the later stages, the bleeding becomes irregular and possibly heavy. The second symptom is vaginal discharge. In advanced stages, due to cancerous tissue necrosis accompanied by infection, there can be a large amount of foul-smelling, watery, or purulent discharge. The third point about advanced symptoms depends on the extent of the cancerous area involved. Secondary symptoms may appear depending on the adjacent tissues, organs, and nerves affected, including frequent urination, urgency, constipation, swelling and pain in the lower limbs. When the tumor compresses or involves the ureter, it can cause ureteral obstruction, hydronephrosis, and uremia. In the advanced stages, patients may experience symptoms of systemic failure like anemia and cachexia.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Causes of cervical cancer

There are several causes of cervical cancer, such as having multiple sexual partners, premature birth, smoking, and early sexual activity, all of which could lead to cervical cancer. However, the main cause of cervical cancer is infection with HPV, the human papillomavirus. It has been scientifically proven that cervical cancer is caused by HPV infection. Therefore, this viral infection is the primary cause of cervical cancer. It is recommended that women of childbearing age undergo cervical cancer screening to check for any abnormalities in the cervix.

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Written by Xu Xiao Ming
Obstetrics and Gynecology
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Can cervical cancer be cured?

Cervical cancer can be treated with options including surgery, radiotherapy, and chemotherapy. For Stage 1A1 cervical cancer, a conization surgery can be chosen; for stages from 1A2 up to before 2B, a radical hysterectomy with bilateral adnexectomy and pelvic lymphadenectomy can be selected; if it is Stage 2B, where the cancer has spread to the parametrium, it is recommended to first undergo chemotherapy as preoperative neoadjuvant therapy to reduce the tumor size before proceeding with surgery; if the cancer has progressed to Stage 3A1 and beyond, radiotherapy or chemotherapy is recommended. In summary, surgical treatment can be chosen for cervical cancer before Stage 2B; if it is Stage 2B or later, involving the parametrium or the lower third of the vagina, surgery is generally not an option, and the treatment usually involves radiotherapy or chemotherapy.