What should I do if atrophic gastritis causes severe weight loss?

Written by Wu Hai Wu
Gastroenterology
Updated on February 08, 2025
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Patients with atrophic gastritis should be highly attentive if they experience significant weight loss and should receive standardized traditional treatments. Additionally, dietary habits also require careful attention; it is important to quit smoking and drinking alcohol, and to avoid using medications that damage the gastric mucosa, such as nonsteroidal anti-inflammatory drugs and steroids. Furthermore, eating habits should be regular, avoiding binge eating and foods that are too salty, spicy, or that are fried or deep-fried. Active treatment should also be directed against Helicobacter pylori, utilizing medications that protect the gastric mucosa, enhance its resistance to gastric acid, and improve the regenerative ability of gastric mucosal cells. Medications that inhibit bile reflux and improve gastric motility can also be employed.

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Written by Li Ying
Gastroenterology
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Can chronic atrophic gastritis be cured?

Chronic atrophic gastritis is primarily a chronic digestive system disease caused by atypical hyperplasia. It is mainly characterized by upper abdominal dull pain, bloating, loss of appetite, weight loss, anemia, etc., and lacks specificity. It is a disease caused by multiple pathogenic factors and is a precancerous lesion. There are many causes, including Helicobacter pylori infection and dietary factors, among others. Moreover, treatment for atrophic gastritis can be targeted based on the specific condition, clinical symptoms, and auxiliary examinations.

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Written by Wu Hai Wu
Gastroenterology
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Is atrophic gastritis negative a problem?

Atrophic gastritis negative generally means there's no major issue. A negative result for atrophic gastritis indicates that the patient is unlikely to have atrophic gastritis. In such cases, it may be considered that there is chronic superficial gastritis. If the patient has symptoms such as acid reflux, belching, heartburn, nausea, vomiting, etc., the use of proton pump inhibitors can be considered to suppress the secretion of stomach acid, and products such as aluminum magnesium carbonate and sucralfate to protect the gastric mucosa. Treatment to promote gastric motility such as Itopride or Mosapride can also be considered. Additionally, it is necessary to conduct a Carbon-13 urea breath test or Carbon-14 urea breath test to check for Helicobacter pylori infection.

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Written by Si Li Li
Gastroenterology
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How to treat chronic atrophic gastritis with intestinal metaplasia?

The treatment of chronic atrophic gastritis with intestinal metaplasia mainly includes the following aspects: The first is general treatment. Firstly, the diet should be light and easily digestible, avoiding spicy, stimulating, fried, grilled, cold, and sweet foods. It is important to exercise regularly and avoid emotions such as anxiety and depression. The second is the treatment against Helicobacter pylori, including a proton pump inhibitor plus two antibiotics, and a bismuth agent, with a treatment course of 14 days. Additionally, medications that promote gastric motility and protect the gastric mucosa are used. The fourth involves endoscopic treatments, including endoscopic APC treatment or endoscopic mucosal resection. The fifth, combining traditional Chinese medicine, differentiating syndrome treatments and oral herbal medicines, can also achieve good effects.

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Written by Jiang Guo Ming
Gastroenterology
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Is atrophic gastritis serious?

Chronic atrophic gastritis, compared to chronic non-atrophic gastritis, is relatively more severe. It is usually due to the atrophy of the gastric mucosal glands that this condition occurs. Under gastroscopy, the gastric mucosa can be seen to become pale, and the submucosal blood vessels are easily exposed. Sometimes, the gastric mucosal cells are replaced by intestinal epithelial cells, which is what we refer to as intestinal metaplasia. Some believe that this condition is a precancerous lesion, so it must be given sufficient attention. Firstly, it is necessary to check for Helicobacter pylori infection; if present, comprehensive antibiotic treatment is required. Some believe that if Helicobacter pylori is completely eradicated, partial reversal of gastric mucosal atrophy can happen, and in some cases, it may even return to normal, making the eradication of Helicobacter pylori particularly important. If there is no Helicobacter pylori infection, symptomatic treatment is advocated, such as protecting the gastric mucosa, etc. Additionally, traditional Chinese medicine has relatively better effects in treating atrophic gastritis compared to Western medicine, and further diagnosis and treatment in a traditional Chinese medicine department can be considered. (Note: The use of medications should be under the guidance of a professional doctor.)

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Written by Jiang Guo Ming
Gastroenterology
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Atrophic gastritis with intestinal metaplasia what medicine to take

Chronic atrophic gastritis with intestinal metaplasia often arises from untreated chronic superficial gastritis, primarily due to Helicobacter pylori infection. Therefore, it is essential to first check for Helicobacter pylori infection. If an infection is present, quadruple therapy is generally used to eradicate the bacteria, which may improve the atrophy. If there is no Helicobacter pylori infection, treatment mainly involves protecting the gastric mucosa. While there are no specific Western medicines for this, traditional Chinese medicine and a differential diagnosis approach often yield good results. Regular follow-ups are also important. (Specific medications should be used under the guidance of a doctor.)