Chronic atrophic gastritis with erosion requires drug treatment based on the specific symptoms of the patient and whether there is a Helicobacter pylori infection. The infection rate of Helicobacter pylori is very high, often exceeding 50%, so it is also necessary to check for Helicobacter pylori infection in cases of chronic atrophic gastritis. If there is a Helicobacter pylori infection, antibacterial treatment is needed, typically employing a quadruple therapy. If there is no Helicobacter pylori infection, symptomatic treatment is generally used. Common treatments include protecting the gastric mucosa, suppressing gastric acid, and enhancing gastric motility, among others. Additionally, it is important to pay attention to daily diet and lifestyle habits, focusing on light and easy-to-digest foods, and avoiding raw, greasy, spicy, and irritating foods; quitting smoking and drinking can also be helpful. (Specific medication usage should be conducted under the guidance of a doctor.)