Is the right shoulder pain from liver cancer muscular pain?

Written by Sun Ming Yue
Medical Oncology
Updated on March 09, 2025
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Many cancer patients do not exhibit obvious symptoms after becoming ill. This is particularly true for many liver cancer patients who do not feel anything unusual after contracting the disease, leading to a lack of timely detection and treatment. By the time they are diagnosed, the disease has often already reached an advanced stage. At this advanced stage, treatment becomes quite difficult. If a patient experiences severe pain in the right shoulder, it generally indicates that the liver cancer has reached a late stage. The pain during this period has no specific characteristics; it is simply a sensation of pain.

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Written by Yan Chun
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Will people with early-stage liver cancer experience weight loss?

Patients with early-stage liver cancer generally do not experience weight loss; weight loss is more commonly a clinical manifestation in patients with late-stage liver cancer. The reason for weight loss in liver cancer patients is due to the damage caused by cancerous tissue to liver function, leading to reduced synthesis of albumin. Furthermore, patients with liver cancer often experience a significant decrease in food intake, resulting in insufficient intake of nutrients such as albumin. Additionally, the progression of liver cancer tumors requires the consumption of a large amount of the body's albumin. Therefore, due to these factors, many patients with late-stage liver cancer exhibit clinical manifestations of weight loss. Moreover, besides not experiencing weight loss, patients with early-stage liver cancer also do not typically present with typical clinical symptoms. Many patients are asymptomatic, and as the lesion progresses, the cancer spreads, possibly leading to clinical manifestations associated with tumor spread. For example, pain in the liver area, a significant decrease in food intake, fatigue, fever, pain, and some patients may also exhibit symptoms of metastasis such as headaches, vomiting, abdominal pain, and abdominal distension.

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Can hepatitis B turn into liver cancer?

Hepatitis B can gradually develop into cirrhosis or liver cancer. Therefore, if a hepatitis B virus infection is detected, it needs attention. If the hepatitis B surface antigen is positive in the HBV "two-and-a-half" test, it indicates a hepatitis B virus infection. Once infected with the hepatitis B virus, it is necessary to regularly check liver function and hepatitis B virus DNA, as well as have abdominal ultrasounds. If an increase in transaminases is found, it indicates the transformation into chronic hepatitis B, necessitating liver-protecting and enzyme-lowering treatments. If the hepatitis B virus DNA exceeds a certain value, antiviral treatment is also needed. After being infected with the hepatitis B virus, it is crucial to rest and avoid excessive fatigue and staying up late.

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Written by Liu Liang
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How is liver cancer diagnosed?

In clinical practice, if a patient has a history of chronic hepatitis B and imaging tests, such as an enhanced CT or MRI of the liver, suggest a radiological appearance of liver cancer, combined with an AFP level greater than 400 persisting for four weeks, these conditions can support a clinical diagnosis of liver cancer. However, for a confirmed diagnosis, a liver biopsy guided by ultrasound or CT must be performed. The definitive diagnosis of liver cancer relies on identifying cancer cells through pathological examination.

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Do early-stage liver cancer patients experience fatigue?

Patients with early-stage liver cancer generally do not exhibit symptoms of fatigue, which are more commonly seen in patients with mid to late-stage liver cancer. The clinical symptoms of early-stage liver cancer are generally not typical, with a minority of patients experiencing reduced appetite and discomfort or mild pain in the liver area. Furthermore, early-stage liver cancer is often discovered during physical examinations or incidentally. Fatigue in liver cancer patients is mostly due to hypoalbuminemia, moderate to severe anemia, or toxic side effects caused by certain anticancer treatments. Hypoalbuminemia occurs because the growth of liver cancer consumes a large amount of protein, and liver dysfunction leads to insufficient synthesis of both protein and glycogen, resulting in malnutrition in patients. After experiencing weight loss, patients often show signs of fatigue. The pathological changes in liver cancer can lead to moderate to severe anemia, which, in turn, significantly contributes to fatigue. Additionally, some medications used in treating liver cancer can cause fatigue due to their toxic side effects.

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Will "small three yang" lead to liver cancer?

Hepatitis B "minor three positives" refers to positivity in the first, fourth, and fifth items of the complete hepatitis B panel. It is common among patients with acute and chronic hepatitis B. There is no necessary correlation between "minor three positives" and cancer. While some patients with "minor three positives" may develop liver cancer, not all liver cancer patients necessarily progress from this condition, indicating no inevitable link between the two.