Primary liver cancer causes

Written by Liu Liang

Oncology

Updated on January 20, 2025

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The causes and specific mechanisms of primary liver cancer are not yet very clear; its development is a complex process involving multiple factors and steps, influenced by various aspects such as environment and diet. Primary liver cancer is associated with chronic hepatitis B and C virus infections, aflatoxin, contaminated drinking water, and alcoholic cirrhosis, among other factors. Particularly, hepatocellular carcinoma has a significant association with hepatitis B, and most patients may also have a history of chronic hepatitis B.

Other Voices

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Written by Luo Han Ying

Endocrinology

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Can pain around the belly button be liver cancer?

The tissues around the navel are primarily intestinal tissues. The outer ring is the large intestine, and close to the navel is mainly the small intestine. If there is pain around the navel that feels like pulling or bloating, and it relieves after defecation, then it is generally enteritis. The liver, on the other hand, is located in the upper right part of the abdomen, below the rib margin. If pain occurs in this area, the possibility of liver cancer is high, and the two types of pain are completely different. Pain around the navel is mainly pulling pain, and it is not very severe; whereas liver pain is primarily bloating pain, which is very severe, and general medications cannot alleviate it. Therefore, pain around the navel is unlikely to be liver cancer.

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Written by Cui Fang Bo

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How to reduce fever in late-stage liver cancer

For late-stage liver cancer patients experiencing fever, antipyretic treatment should be based on different circumstances. If the fever is due to an infection, it often exceeds 39℃ and is accompanied by symptoms and signs related to the infection, such as cough and yellow sputum, abdominal pain, diarrhea, frequent urination, urgency, and painful urination. In such cases, antibiotics should be used for anti-infective treatment, along with antipyretic analgesics for fever reduction. If the fever is due to tumor fever or interventions like liver procedures, there are no infection-related factors, usually the temperature does not exceed 38.5℃, and there are no symptoms or signs related to infection. The treatment primarily involves the use of antipyretic analgesics for fever reduction.

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Written by Yan Chun

Oncology

1min 14sec

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Why can't people with liver cancer drink milk?

Liver cancer patients are generally advised not to drink milk, particularly in cases of advanced liver cancer where there is a potential for hepatic encephalopathy. This is because, for patients in the late stages of liver cancer, liver function is compromised, and some may already exhibit symptoms indicative of pre-hepatic encephalopathy. Consuming a diet rich in protein can easily trigger hepatic encephalopathy, and since milk is high in protein, its consumption is usually limited or avoided in such patients. However, for the majority of liver cancer patients, drinking milk is permissible as it not only contains abundant protein but also rich calcium, which is beneficial for the recovery of liver cancer patients. Most liver cancer patients have hypoalbuminemia (low levels of protein in the blood) and some also have hypocalcemia (low levels of calcium in the blood), thus the intake of calcium and protein-rich foods can be very beneficial for their recovery.

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Written by Sun Wei

Surgical Oncology

57sec

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The difference between primary liver cancer and secondary liver cancer

Primary liver cancer, also commonly referred to as liver cancer, originates in the liver itself and is not transferred from other parts of the body. Secondary liver cancer occurs when the primary tumor originates in another location and then metastasizes to the liver, causing hepatic space-occupying lesions; this is referred to as secondary liver cancer. The main difference between the two types is their origin. Additionally, primary liver cancer is often solitary but may develop intrahepatic or distant metastases as the disease progresses. In cases of secondary liver cancer, multiple intrahepatic metastatic lesions may be discovered at the onset. Moreover, primary liver cancer may often display an elevated alpha-fetoprotein tumor marker, whereas this marker might be normal in secondary liver cancer.

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Written by Sun Wei

Surgical Oncology

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Is primary liver cancer prone to metastasis?

Primary liver cancer's likelihood of metastasis depends on its pathological staging. If detected in the middle or late stages, it is more likely to metastasize. The most common sites of metastasis for primary liver cancer include intrahepatic and nearby digestive organs, such as the gastrointestinal tract and the peritoneum. Additionally, primary liver cancer can also spread through the bloodstream and the lymphatic system, reaching distant locations like the lungs, brain, and bones. If primary liver cancer cannot be surgically treated, the treatment options are limited, and the survival time is generally short, with an average lifespan of about one to two years.