Is primary liver cancer prone to metastasis?

Written by Sun Wei
Surgical Oncology
Updated on September 25, 2024
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Primary liver cancer's likelihood of metastasis depends on its pathological staging. If detected in the middle or late stages, it is more likely to metastasize. The most common sites of metastasis for primary liver cancer include intrahepatic and nearby digestive organs, such as the gastrointestinal tract and the peritoneum. Additionally, primary liver cancer can also spread through the bloodstream and the lymphatic system, reaching distant locations like the lungs, brain, and bones. If primary liver cancer cannot be surgically treated, the treatment options are limited, and the survival time is generally short, with an average lifespan of about one to two years.

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Should the gallbladder be removed in the early stage of liver cancer?

Whether early-stage liver cancer patients need to have their gallbladder removed depends on the location of the tumor. For liver cancers located close to the gallbladder, gallbladder removal is generally necessary. For liver cancer lesions that are farther from the gallbladder, it is usually sufficient to only remove the liver tumor, or to perform a resection of the local liver segment or sub-segment. Additionally, for early-stage liver cancer patients to undergo surgery, certain conditions must be met: the tumor must be five centimeters or smaller, there should be no cancerous thrombus in the main trunk of the portal vein, the liver cancer tumor should not involve the semi-dry or full-dry circumstances, and the liver function should be compensatory. Under these conditions, an effort should be made to perform liver tumor resection. Generally, cancers located in the left lobe of the liver require local resection, either of a liver segment or sub-segment, and sometimes resection of the liver lobe may be performed. Tumors located in the right lobe of the liver or the hepatic portal area require local tumor resection.

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Will having hepatitis B antibodies lead to liver cancer?

Firstly, there is no necessary connection between liver cancer and antibodies, but if a patient has hepatitis B antibodies, then the chance of this patient contracting hepatitis B is very small. Relatively speaking, since hepatitis B can develop into liver cancer, having positive hepatitis B antibodies might reduce the chance of developing liver cancer. However, there are many types of liver cancer, and its causes are varied, including hepatitis B, hepatitis C, and other factors.

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The difference between primary liver cancer and metastatic liver cancer

Primary liver cancer refers to malignant tumors that originate in the liver, while metastatic liver cancer refers to cancers that start in other parts of the body and then spread to the liver through lymphatic and blood circulation, among other routes. Another difference is that primary liver cancer is more likely to be a single lesion, while metastatic liver cancer generally involves multiple lesions. Regarding the differences between primary and metastatic liver cancer, their treatment methods also differ. For primary liver cancer, interventional chemotherapy or surgery, such as hepatic lobectomy, can be performed if the tumor is small. In contrast, metastatic liver cancer usually involves multiple lesions, making surgery alone challenging. Additionally, the primary tumor also requires treatment.

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Will Hepatitis B "big three yang" turn into liver cancer?

Patients with severe hepatitis B, if not treated in time or improperly or for an inadequate duration, may progress to develop liver cirrhosis. A portion of those with cirrhosis might then develop liver cancer. Therefore, patients with severe hepatitis B could potentially develop liver cancer if left untreated or not properly treated. Therefore, once diagnosed with hepatitis B, particularly severe forms, prompt and standardized treatment should be sought to achieve an antiviral response against hepatitis B and prevent the occurrence of liver cirrhosis and liver cancer.

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What should I do if I have liver cancer and a fever of 38 degrees Celsius?

Liver cancer patients experiencing a fever of 38°C can be seen in the following scenarios: The first type is tumor-related fever. In liver cancer patients, especially those in the advanced stages or with large tumors, a fever of around 38°C can occur in the absence of infection symptoms. This tumor fever is related to various mediators released into the blood by the tumor. The second type is infectious fever. Cancer patients undergoing anti-tumor treatment may experience immunosuppression and concurrent infections. This type of fever often exceeds 38.5°C but can also occur around 38°C in the early stages, often accompanied by symptoms of infection such as coughing, sputum production, abdominal pain, and diarrhea. The third type is treatment-related fever. Patients with liver cancer may experience a fever of around 38°C on the day of and several days following interventional treatments.